Clinical trials: Vaping Behavior, open to volunteers
Tobacco Use Cessation, Addiction
An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use.
- Trial name
- NCT06483412
- Testing
- Healthy Futures: Alternative-to-Suspension Curriculum
- Where
- United States
- Volunteers
- 2,540 people, healthy volunteers welcome
- Sponsor
- Stanford University
Smoking Cessation, Obesity and Obesity-related Medical Conditions
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
- Trial name
- CRESCENT (NCT06948058)
- Testing
- Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brown University
E-cigarette Use, Cigarette Smoking Risk
An Online Intervention to Reduce E-cigarette Use and Cigarette Smoking Risk in Adolescents
The goal of this clinical trial is to learn if a brief digital intervention can reduce e-cigarette use and prevent cigarette smoking initiation in teenagers ages 12-17.
- Trial name
- NCT07624292
- Testing
- Virtual Intervention for Behavioral Empowerment (VIBE)
- Volunteers
- 150 people
- Sponsor
- University of Southern California
HIV, Smoking
Reduce Tobacco Use in People Living With HIV in Switzerland
The purpose of this trial is to test the effectiveness of offering a menu of different tobacco smoking substitutional products (e-cigarettes, nicotine pouches, nicotine patches in addition to usual of care) for smokers in the…
- Trial name
- RETUNE (NCT06789692)
- Testing
- tobacco smoking substitution products
- Where
- 7 sites in Switzerland
- Volunteers
- 972 people
- Sponsor
- University Hospital, Basel, Switzerland
Tobacco Use Disorder, Nicotine Dependence
TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System
Background: Tobacco smoking and vaping remains public health concern, with many adults continuing to experience difficulties accessing appropriate support for smoking cessation in Switzerland and Türkiye.
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Vaping, Smoking Tobacco
- Trial name
- TUBSIS_2_0 (NCT07568483)
- Testing
- TUBSIS 2.0
- Where
- Switzerland
- Volunteers
- 406 people
- Sponsor
- University of Zurich
Cigarette Smoking, E-cigarette Use
Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing
This study will investigate the effects of a very-low-nicotine cigarette (VLNC) standard, e-cigarette price, and illegal cigarette price on illegal product purchasing and alternative product use in a virtual marketplace.
- Trial name
- NCT07161050
- Testing
- Nicotine Content, Illegal cigarette price, E-cigarette price
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Virginia Polytechnic Institute and State University
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
NO VAPE + 12 Weeks of Standard CBT, Sham NO VAPE + 12 Weeks Standard CBT
Trial of Novel, On-Demand Virtual Reality to Amplify Practice Efficacy (NO VAPE) Added to Cognitive Behavioral Therapy for Nicotine Vaping Cessation
3. General Description of Study Design The proposed study will evaluate the effect of adding a VR app with CBT-embedded content to a 12-session individual CBT treatment program.
- Trial name
- NO VAPE (NCT07223879)
- Testing
- NO VAPE VR app with CBT-embedded content with a 12-session individual CBT treatment program
- Volunteers
- 90 people
- Sponsor
- Charles River Analytics
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Vaping, Pregnancy Related
The Impact of E-cigarettes During Pregnancy on Childhood Health Outcomes Study
Tobacco smoking in pregnancy is now widely accepted as having adverse health outcomes for both the mother and fetus. Tobacco smoking in pregnancy is associated with increased incidence of miscarriage, stillbirth and preterm birth…
- Conditions
- Vaping, Pregnancy Related, Pediatric Respiratory Diseases
- Trial name
- ECHO (NCT06297005)
- Where
- 3 sites in Ireland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Hypertension, Tobacco Cigarette Smoking
Cardiovascular Impacts of E-cigarettes Among Older Adults
This study will compare the cardiovascular effects of continued smoking with those of e-cigarette (EC) use among older adults with hypertension.
- Conditions
- Hypertension, Tobacco Cigarette Smoking, Electronic Cigarettes, Cardiovascular
- Trial name
- NCT07880704
- Testing
- Nicotine E-cigarette, Tobacco Cigarette
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
E-cigarette, Alcohol
Flavored Ready-to-Drink Alcohol Restriction in Young Adults: Behavioral and Biomarker Outcomes
This pilot randomized behavioral study evaluates the feasibility, adherence, and acceptability of an intervention to restrict flavored ready-to-drink (RTD) alcoholic beverages among young adults who regularly use both alcohol and…
- Trial name
- NCT07840625
- Testing
- Flavored Ready-to-Drink alcoholic beverage use restriction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
E-Cig Use
Hyperpolarized Xenon-129 MR Imaging of the Lung
Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial…
- Trial name
- e-cigarette (NCT04662658)
- Testing
- Hyperpolarized Xenon -129 MRI
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Nicotine Dependence, Tobacco Use
Puff Topography and Sensory Effects Across IQOS Device Generations
The goal of this clinical trial is to learn how people use two generations of IQOS heated tobacco devices and how each device affects their smoking behavior and sensory experience.
- Trial name
- NCT07712887
- Testing
- IQOS Iluma i with TEREA Tobacco Sticks, IQOS 2.4 with HEETS Tobacco Sticks
- Where
- 2 sites in Lebanon
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Smoking Electronic Cigarettes (Vaping), With Moderate and High Dependence for Nicotine
EFFECT OF WIM HOF BREATHING EXERCISE ON VENTILATORY FUNCTIONS IN SMOKERS
Cigarette smoking is the most common form of tobacco use worldwide, but other tobacco products, such as e-cigarettes, cigars, cigarillos, roll-your-own, pipes, and various smokeless tobacco products are also damaging.
- Trial name
- NCT07153640
- Testing
- 1 ) Wim Hof Breathing Exercise, 2) Aerobic exercises
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- October 6 University
Dual Use of Cigarettes and E-cigarettes
DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use Pharmacotherapy
This randomized clinical trial evaluates the effectiveness of augmented-dose combination nicotine replacement therapy (NRT) versus standard-dose NRT and no-NRT control for cessation of dual combustible cigarette (CC) and…
- Trial name
- NCT07754578
- Testing
- Text- and web-based support, Nicotine Replacement Therapy (NRT, nicotine patch), Nicotine replacement therapy lozenge
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- Medical University of South Carolina
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Nicotine Dependence, Transcranial Magnetic Stimulation
Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
The goal of this clinical trial is to learn if a combination of varenicline and enhanced accelerated Transcranial Magnetic Stimulation (aTMS) works to help adults quit using nicotine products.
- Conditions
- Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation
- Trial name
- V-TMS (NCT07145866)
- Testing
- Varenicline, Transcranial Magnetic Stimulation, Nicotine Cessation Counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Tobacco-flavored EC, Sweet-Cooling EC
Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine
This project aims to investigate the impact of e-cigarette flavors and usage patterns on achieving harm-reduction milestones in a sample of cigarette smokers with opioid use disorder who are taking buprenorphine
- Conditions
- Tobacco-flavored EC, Sweet-Cooling EC, Sweet Non-cooling EC
- Trial name
- SWITCH (NCT07202039)
- Testing
- Brief individual counseling sessions
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Prisma Health-Upstate