Clinical trials: Vaping Related Disorder
Schizophrenia, Schizophreniform Disorder
Electronic Cigarettes in Smokers With Mental Illness
People with mental illness are more likely to smoke and are more severely addicted to nicotine than the general population. As a result, the number of deaths related to tobacco is higher.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Bipolar Disorder
- Trial name
- APUS e-Cigs (NCT02212041)
- Testing
- disposable electronic cigarettes
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College London
Tobacco-flavored EC, Sweet-Cooling EC
Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine
This project aims to investigate the impact of e-cigarette flavors and usage patterns on achieving harm-reduction milestones in a sample of cigarette smokers with opioid use disorder who are taking buprenorphine
- Conditions
- Tobacco-flavored EC, Sweet-Cooling EC, Sweet Non-cooling EC
- Trial name
- SWITCH (NCT07202039)
- Testing
- Brief individual counseling sessions
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Prisma Health-Upstate
Vaping, Vaping Cessation
Social Media Support Groups for Adolescent Vaping Cessation
The purpose of this study is to pilot test feasibility and acceptability of the Quit the Hit Toolkit, a social media-based nicotine vaping cessation program for adolescents and young adults, adapted for use in community settings.
- Conditions
- Vaping, Vaping Cessation, Nicotine Dependence
- Trial name
- NCT07540780
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
E-cigarette Use, Vaping
A Trial of Varenicline for E-cigarette Cessation
This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is efficacious for quitting e-cigarettes.
- Conditions
- E-cigarette Use, Vaping, Nicotine Dependence
- Trial name
- NCT07040566
- Testing
- Varenicline 1mg BID
- Where
- 2 sites in United States
- Volunteers
- 326 people
- Sponsor
- Yale University
Nicotine Dependence, Nicotine Vaping
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
In a crossover study, experienced electronic cigarette users will vape 3 different forms of nicotine: natural (derived from tobacco), synthetic, or a 50:50 mixture of both natural and synthetic.
- Trial name
- NCT05962229
- Testing
- (S)-Nicotine, (R)- nicotine, Racemic nicotine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cannabis Use, Tobacco Use
Effect of Cannabis on E-Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Electronic Cigarette Use
- Trial name
- NCT06609109
- Testing
- THC High Dose, THC Low Dose, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
E Cigarette Use, Vaping
Acute Effects of TCIG vs ECIG in PLWH
Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization and inflammation/oxidative stress.
- Conditions
- E Cigarette Use, Vaping, Smoking, Tobacco Smoking
- Trial name
- NCT04568395
- Testing
- TCIG, ECIG
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of California, Los Angeles
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-1 (NCT03839745)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence, Nicotine Dependence, Cigarettes
Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.
A Randomized Study Comparing Nicotine Pharmacokinetics of Seven Electronic Cigarette Products and One Traditional Cigarette Across Two Delivery (10 puff and ad- libitum) Conditions, in Healthy Adult Smokers
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03700112
- Testing
- JUUL Virginia Tobacco flavored 5.0% ENDS, PMI iQOS Heat sticks, Reynolds VUSE Solo ENDS - Original
- Where
- New Zealand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Nicotine Dependence, Transcranial Magnetic Stimulation
Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
The goal of this clinical trial is to learn if a combination of varenicline and enhanced accelerated Transcranial Magnetic Stimulation (aTMS) works to help adults quit using nicotine products.
- Conditions
- Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation
- Trial name
- V-TMS (NCT07145866)
- Testing
- Varenicline, Transcranial Magnetic Stimulation, Nicotine Cessation Counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
E-cigarette Use, Cigarette Smoking Risk
An Online Intervention to Reduce E-cigarette Use and Cigarette Smoking Risk in Adolescents
The goal of this clinical trial is to learn if a brief digital intervention can reduce e-cigarette use and prevent cigarette smoking initiation in teenagers ages 12-17.
- Trial name
- NCT07624292
- Testing
- Virtual Intervention for Behavioral Empowerment (VIBE)
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Vaping, Vaping Teens
Behavioral Intervention for Youth to Promote Vaping Cessation
This study will test the hypothesis that the QuitVaping (QV) intervention and additional texting support will improve nicotine abstinence rates in adolescents as compared to Enhanced Usual Care (EUC: education about nicotine…
- Conditions
- Vaping, Vaping Teens, Nicotine Dependence
- Trial name
- VIA (NCT06765291)
- Testing
- QuitVaping, This is Quitting (TIQ)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Nicotine Vaping, Nicotine Dependence
Nicotine and Pavlovian Bias
Nicotine remains a major cause of health problems in the US and around the world. Insight into the behavioral changes induced by nicotine use may help advance the understanding of the mechanisms underlying the maintenance of…
- Trial name
- NCT06027723
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Tobacco Use Disorder
Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
In this pilot study, menthol cigarette smokers will be randomized to one of three experimental marketplaces: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes (condition A); 2) a condition…
- Trial name
- NCT03402243
- Testing
- Menthol ban on cigarettes, Menthol ban on cigarettes and e-cigarettes, No menthol ban
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Susceptibility to Electronic Cigarette Use
The purpose of the study is to explores various psycho-social, physiological, cognitive, behavioral, and environmental factors that may affect the association between pulmonary status and Susceptibility to Electronic Cigarette Use
- Trial name
- NCT04151784
- Testing
- Pulmonary Group, Healthy Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham