Clinical trials: Variability
Pre Diabetic, Obesity & Overweight
The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity
This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with…
- Trial name
- CGM (NCT07423065)
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- 3 sites in Slovenia
- Volunteers
- 34 people
- Sponsor
- University of Primorska
Healthy Adults
Effects of High-intensity Interval Training and Moderate-intensity Continuous Training on Functioning of Attentional Networks and Heart Rate Variability in Healthy Adults
This study investigated the effects of HIIT and MICT on functioning of attentional networks and explored the relationship between heart rate variability (HRV) and these networks in healthy adults.
- Trial name
- NCT06602700
- Testing
- HIIT, MICT
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Diabetes
This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00659295)
- Testing
- insulin detemir
- Where
- 13 sites in Belgium, Czechia and 11 more
- Volunteers
- 51,170 people
- Sponsor
- Novo Nordisk A/S
Immunosuppression After Kidney Transplantation
PEL-1235_REN-0176-I (Pelicon)
Aim of this study is to investigate whether in patients following kidney transplantation (>6 months after transplantation), the intra-patient variability of levels of tacrolimus is comparable after administration of tacrolimus…
- Trial name
- Pelicon (NCT01904045)
- Testing
- tacrolimus Advagraf, tacrolimus Prograf
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Technical University of Munich
Ultrasound, Catheterization
Success of Internal Jugular Vein Catheterization
Internal jugular vein cannulation can be performed with the blind technique under ultrasound (USG) guidance or using classical marker points.
- Conditions
- Ultrasound, Catheterization, Volume Status
- Trial name
- NCT05717556
- Testing
- Internal Jugular Vein Catheterization
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Congenital Adrenal Hyperplasia, Exercise Capacity
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH
Congenital Adrenal Hyperplesia (CAH) is a group of automosal recessive disorders that develop due to a deficiency of one of the five enyzmes necessary for cortisol synthesis in the adrenal cortex.
- Conditions
- Congenital Adrenal Hyperplasia, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06449456
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Nasal Cavity
Evaluation of Inter-patient Variability Size of the Nasal Cavity, Based on CT Scans
This study is part of the french research program ANR NEMRO "MICROROBOTIC NASAL ENDOSCOPY BY OPTICAL COHERENCE TOMOGRAPHY: IMPACT OF SMELL DEFICIENCY ON NEURODEGENERATIVE DISEASES." Recent studies have shown a strong correlation…
- Trial name
- NEMROfentes3D (NCT02879253)
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Progressive Muscle Relaxation
Acute Effects of Progressive Muscle Relaxation on Brain Waves
In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response.
- Trial name
- NCT07089537
- Testing
- progressive muscle relaxaiton, Rest
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Postprandial Glucose, Glucose Levels
Ultra-processed Food-reducing Intervention and Continuous Glucose Monitoring
The goal of this trial is to investigate whether reduction in ultra-processed food intake through dietary counseling and education can improve postprandial glucose responses and glycemic variability compared with a usual diet in…
- Conditions
- Postprandial Glucose, Glucose Levels, Hyperglycemias
- Trial name
- ULTRA-CGM (NCT07175701)
- Testing
- 40-minute one-on-one dietary counseling and nutrition education aimed at reducing ultra-processed food consumption, Standard dietary counseling and nutrition education based on national guidelines
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Korea University
Exercise, Healthy Participants
Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial
The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes.
- Conditions
- Exercise, Healthy Participants, Glucose Variability, Type 1 Diabetes (T1D)
- Trial name
- NCT07209930
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Vascular Ehlers-Danlos Syndrome
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Vascular Ehlers-Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein.
- Trial name
- NCT05994664
- Testing
- Heartmath Intervention, Control Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Idiopathic Thrombocytopenia Purpura
A Study to Evaluate the Relative Bioavailability and Intra-Subject Variability of Two Lots of E5501 40 mg Tablets Administered Twice as Single Oral Doses to Healthy Subjects
The purpose of this study is to evaluate the relative bioavailability (BA) of two lots of E5501 40 mg tablets administered twice as single oral doses to healthy subjects.
- Trial name
- NCT01289509
- Testing
- E5501, Drug: E5501
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Type 2 Diabetes Mellitus
Comparison of Exenatide vs. Biphasic Insulin Aspart 30 on Glucose Variability in Type 2 Diabetes
This is a multi-centre, open-label, randomized, parallel trial to compare the effect of Exenatide versus Biphasic insulin Aspart 30 on glucose variability and inflammatory markers in type 2 diabetes mellitus (T2DM) patients…
- Trial name
- NCT02449603
- Testing
- Exenatide, Biphasic insulin Aspart 30
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Acute Respiratory Insufficiency
Respiratory Variability in Patients With Acute Hypoxemic Respiratory Failure and Placed on High Flow Oxygen Therapy
Recommendations from the European Respiratory Society are to use high-flow oxygen therapy rather than conventional oxygen therapy and non-invasive ventilation (NIV) in cases of acute hypoxaemic respiratory failure.
- Trial name
- HYPOXEVARIA (NCT06675045)
- Testing
- Respiratory variability monitoring
- Where
- France
- Volunteers
- 60 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Hypophosphatasia
Burden of Disease in Hypophosphatasia (HPP)
Hypophosphatasia (HPP) is a rare, inherited metabolic disease caused by inactivating mutations in the Alkaline Phosphatase (ALPL) gene, coding for the Tissue-nonspecific alkaline phosphatase (TNAP).
- Trial name
- NCT02291497
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Wuerzburg University Hospital
Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV)
taVNS During Multi-site HRV Measurement: Reliability & Agreement Study
This study examines the reliability and agreement of autonomic nervous system measurements obtained from different anatomical sites during transcutaneous auricular vagus nerve stimulation (taVNS).
- Conditions
- Autonomic Nervous System (ANS) Functioning and Mood State, Heart Rate Variability (HRV), Blood Pressure Monitoring, Transcutaneous Electric Nerve Stimulation
- Trial name
- taVNS-HRV (NCT07548723)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Chronic Fatigue Syndrome
A Rehabilitation Program for Adolescents With Chronic Fatigue Syndrome
The aim of the programme is to develop a treatment model for adolescents with Chronic Fatigue Syndrome. The program consists of 4 elements lasting for 12 months, psychoeducation reflecting the current knowledge about the disease…
- Trial name
- NCT01806246
- Testing
- integrative rehabilitation program
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- St. Olavs Hospital
Type I Diabetes
Epigenetic Modifications of Diabetes Mellitus Type I
This research is being done to find out if significant changes in blood glucose cause bad outcomes in patients with diabetes.
- Trial name
- NCT01623388
- Testing
- Oral glucose tolerance test for Phase I
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Polycystic Ovary Syndrome
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome
We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability…
- Trial name
- fops (NCT00620529)
- Testing
- Ocean Nutrition 2050, Olive oil capsules
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Keogh Institute for Medical Research
Anesthesia, Neuromuscular Blockade
The Effect of Neuromuscular Blockade on the Composite Variability Index (CVI) During Laryngoscopy
The Bispectral Index (BIS) monitor is used in many operating rooms to provide information to the anesthesiologist about a patient's level of consciousness.
- Trial name
- NCT01450813
- Testing
- Saline 0.06 ml/kg, Rocuronium 0.2 mg/kg, Rocuronium 0.4 mg/kg
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medtronic - MITG
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