Clinical trials: Variability
Parkinson Disease, Healthy Aging
Longitudinal Analysis of Gait Variability to Predict Falls in Parkinson's Disease
The broad goal of this research project is to improve the prediction of falls in patients with Parkinson's disease (PD) through a comprehensive multidisciplinary approach that includes longitudinal measurements of walking…
- Trial name
- NCT04339543
- Testing
- Cognitive dual-task walking
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Depressive Symptoms, Stress Disorder, Acute
Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)
In brief, ART is an innovative "mind-body" (body-centric) psychotherapy that makes use of established core components of trauma-focused therapy including imaginal exposure and imagery rescripting to promote memory…
- Conditions
- Depressive Symptoms, Stress Disorder, Acute, Prolonged Grief Disorder, Alcohol Abuse
- Trial name
- M-ART (NCT04121884)
- Testing
- Accelerated Resolution Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Florida
Cardiovascular Diseases, Coronary Disease
Heart Rate Variability and Sudden Cardiac Death
To evaluate the ability of heart rate variability to identify myocardial infarction patients at high risk of dying, particularly from sudden cardiac death.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005235
- Where
- United States
- Volunteers
- 715 people
- Sponsor
- Columbia University
Systolic Heart Failure
DECIDE-HF: Heart Rate Variability in Heart Failure Patients
The purpose of this study is to determine whether heart rate variability-like parameters are related to changes in the disease status of a subject that suffers from a disease that decreases the pumping function of the heart.
- Trial name
- DECIDE-HF (NCT00949676)
- Where
- 5 sites in Belgium, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Medtronic BRC
To Establish a Standardized Background Parenchimal Enhancement Classification System
From Variability to Standardization: The Impact of Breast Density on Background Parenchymal Enhancement in Contrast-Enhanced Mammography and the Need for a Structured Reporting System
This retrospective study includes 213 patients who underwent CEM, mammography (MG), and ultrasound (US) between May 2022 and June 2023 at the P.O. 'A. Perrino' Hospital, Brindisi.
- Trial name
- NCT06838117
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- Graziella di Grezia
Stress Disorders, Post-Traumatic
HIRREM in Military Personnel
The purpose of this study is to evaluate the effects associated with the use of in-office High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) for participants with symptoms of military-related…
- Trial name
- NCT03230890
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Alcohol Drinking, Alcohol Abuse
Novel Real-world Methods in Social Drinkers and AUD
This research project proposes a novel approach to elucidate the biological adaptations associated with Alcohol Use Disorder and to assess whether such adaptations are predictive of higher alcohol craving in response to both…
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- ALR (NCT05155176)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University
Clexane is Administered to Healthy Volunteers
A Single-Dose Trial to Examine the Within Subject Variability of Clexane® in Healthy Adults Under Fasting Conditions
Primary: To examine the within subject variability of Clexane (80 mg) in healthy male and female volunteers administered subcutaneously (s.c.) as a single dose, in two periods, under fasting conditions.
- Trial name
- NCT02081950
- Testing
- Enoxaparin sodium
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chemi S.p.A.
Health Behavior, Work Related Stress
HRV and Coaching Preparation Phase Study
This pilot study will evaluate possible intervention components to be included in a future stress management and health behaviour change trial and to pilot test their feasibility and acceptability in a small sample.
- Conditions
- Health Behavior, Work Related Stress, Job Stress, Anxiety Depression
- Trial name
- NCT05150574
- Testing
- Core Health Program, Daily resting HRV, Momentary HRV feedback
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brock University
Diabetes Mellitus Type 2
Medium-term Effects of a Polyphenol-rich Beverage Based on Red Grape Pomace Extract on Non-alcoholic Fatty Liver Disease, Cardiometabolic Risk Profile and Gut Microbiota in Subjects with Type 2 Diabetes
Nonalcoholic fatty liver disease (NAFLD) is a liver disease characterized by an abnormal accumulation of fat not due to alcohol or drug consumption that can evolve into steatohepatitis (NASH), fibrosis and cirrhosis.
- Trial name
- PoLiFat (NCT06895018)
- Testing
- Supplementation with Polyphenol Rich Drink
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Diabetes Mellitus, Type 1
Dapagliflozin in Physical Exercise in Type 1 Diabetes
Inhibitors of sodium-dependent glucose-transporter 2 (SGLT-2 inhibitors, including dapagliflozin) inhibit glucose reabsorption in renal tubular cells, hereby increasing glycosuria in the hyperglycemic state.
- Trial name
- NCT04049110
- Testing
- Forxiga 10mg
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypertension, Insulin Resistance Syndrome
Cf-PWV and TyG Index Study
This study aims to investigate how metabolic health is related to arterial stiffness and daily blood pressure patterns. High blood pressure is one of the leading causes of heart disease worldwide, but cardiovascular risk is not…
- Conditions
- Hypertension, Insulin Resistance Syndrome, Arterial Stiffness, Cardiovascular Risk
- Trial name
- RIGID-TyG (NCT07589374)
- Where
- Brazil
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Postoperative Nausea and Vomiting, Postoperative Pain, Acute
The Correlation Between Intraoperative End Tidal Carbon Dioxide, Perfusion Index and Pulse Variability Index on Postoperative Nausea Vomiting and Pain
Postoperative pain, which is frequently encountered in laparoscopic operations, has been examined in different studies with end tidal CO2 (end tidal carbon dioxide), total insufflated gas amount and PI (Perfusion index)…
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Acute, End Tidal Carbon Dioxide, Perfusion Index and Pleth Variability Index
- Trial name
- NCT06865378
- Testing
- Carbon dioxide (CO2) gas insufflation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Naime Yalçın
Weight Loss, Hormone Disturbance
Effects of Weight Loss on Nutritional Mediated Hormone Secretion
Investigative trial with aim of 1. the description of the hormonal and metabolic response to meals containing different compositions of macronutrients 2.
- Conditions
- Weight Loss, Hormone Disturbance, Weight Gain
- Trial name
- RepDiet (NCT02649907)
- Testing
- nutritional stimulation via different testmeals, Nutritional counseling, formula diet
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Participants, Healthy Young Adults
Foam Rolling, Blood Pressure and Range of Motion
Foam rolling (FR) is a technique involving the application of external pressure to muscles and connective tissues using different devices (e.g.
- Trial name
- NCT07433543
- Testing
- Cervical foam rolling
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Head and Neck Cancers
SOMESThesia and ALIMentation
Cancer patients are at high risk for undernutrition. A study with head and neck cancer patients showed that 50% suffered from undernutrition (Prevost et al., 2014).
- Trial name
- SOMEST'ALIM (NCT05272917)
- Testing
- Sensorial tests, food preferences questionnaires
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Type-1 Diabetes
Search for a Link Between the Different Variables for Glycaemia and Oxidative Stress or Impaired HDL Function
As glycaemic variability on the one hand and hypoglycaemia on the other are associated with oxidative stress and inflammation, they are likely, in type-1 diabetic patients, to affect the oxidation of lipoproteins and HDL…
- Trial name
- Holter Gly (NCT02862860)
- Testing
- blood sample, urine sample, installation of Holter
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hypercholesterolemia, Osteoporosis
Food Matrix and Genetic Variability as Determinants of Bioavailability and Biological Effects of Beta-cryptoxanthin and Phytosterols
Regular consumption of a beverage containing β-cryptoxanthin (b-Cx) and plant sterols (Ps) has been shown to exert a synergic effect in reducing cardiovascular risk and bone remodeling markers (formation and resorption).
- Trial name
- foodmagenpol (NCT02065024)
- Testing
- b-cryptoxanthin plus phytosterols
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Status Asthmaticus
Pleth Variability and Asthma Severity in Children
Research has shown that pleth variability can be used to assess asthma severity in children with status asthmaticus. The investigators would like to use an FDA-cleared monitor (Masimo Radical 7) which measures Pleth Variability…
- Trial name
- NCT02302261
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Northwell Health
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