Clinical trials: Variability
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Restenosis or Adverse Cardiovascular Event
Endothelial Function and Heart Rate Variability After Stenting
The objective of this study is to evaluate whether impaired endothelial function and low heart rate variability are associated with clinical restenosis after percutaneous coronary intervention with stent implantation in patients…
- Trial name
- FUNKIS (NCT00999323)
- Testing
- stent implantation in coronary artery
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Type 2 Diabetes Mellitus (T2DM), Cognitive Dysfunction
SGLT2 Inhibitors and Cognitive Function in Adults With Type 2 Diabetes (SaveMinD)
This study is a prospective, randomized, open-label trial with blinded outcome assessment (PROBE design) designed to evaluate the effects of sodium-glucose cotransporter-2 (SGLT2) inhibitor therapy on cognitive function in adults…
- Trial name
- SaveMinD (NCT07694596)
- Testing
- SGLT2 Inhibitor, Standard Diabetes Care
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University of Primorska
Blood Pressure Variability, Intracranial Artery Stenosis
Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis
Correlation study about Blood Pressure Variability and the prognosis of ischemic stroke with intracranial artery stenosis
- Trial name
- NCT01665235
- Testing
- Amlodipine, ACEI / ARB, Aspirin or Clopidogrel
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Weight Loss, Weight Change, Body
Understanding Variability in Behavioral Weight Loss Treatment Response in Young Women (Ready SET Health)
This study is a single-arm behavioral weight loss intervention for emerging adult women with in-person assessments at 0 (baseline) and 4 months (post-treatment) in addition to EMA data collection regarding risk factors known to…
- Conditions
- Weight Loss, Weight Change, Body, Overweight or Obesity
- Trial name
- NCT04875091
- Testing
- Ready SET Health
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Virginia Commonwealth University
Healthy
Safety and Tolerability of Lu AG06479 in Healthy Young Men
The purpose of this study is to investigate the safety and tolerability of Lu AG06479 and what the body does to Lu AG06479 after swallowing single doses of the drug.
- Trial name
- NCT04473651
- Testing
- Lu AG06479
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Lung Cancer, Colorectal Cancer
Heart Rate Variability, Vagus Nerve and Cancer
In France, new cancer cases keep on increasing with around 150 000 deaths yearly. Cancer therapy research is constantly evolving.
- Conditions
- Lung Cancer, Colorectal Cancer, Multiple Myeloma, Non Hodgkin Lymphoma
- Trial name
- NCT04718610
- Testing
- Osteopathic intervention, CRP assessment, QLQ-C30 questionnaire
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Sleep Deprivation
Protective Effect of Statin on Sleep Deprivation
This study aimed to investigate the effect of 48-h sleep deprivation on heart rate variability (HRV) in young healthy people and the protective effect of statin on arrhythmia and HRV.
- Trial name
- NCT02496962
- Testing
- Atorvastatin
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shi Yang
Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Kidney Diseases
Cardiopulmonary Exercise Testing Parameters' Variability in Hemodialysis Patients.
Chronic kidney disease (CKD), especially end-stage kidney disease (ESKD), is associated with increased risk for cardiovascular events and all-cause mortality.
- Trial name
- NCT05557929
- Where
- Greece
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Microvascular Complications, Diabetic Retinopathy
The Effect of the Glycemic Variability on Macular Retinal Microcirculation and Cognitive Functions in Patient With Type 1 Diabetes
Revadiab is case-control study aimed to demonstrate that retinal capillary density is altered in patients with type 1 diabetes with glycemic variability compared to those with comparable glycemic control without glycemic…
- Conditions
- Microvascular Complications, Diabetic Retinopathy, Diabetes, Microangiopathy
- Trial name
- REVADIAB (NCT03821753)
- Testing
- Case, Control
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gestational Diabetes, Continuous Glucose Monitoring
Glucose Variability in Pregnancy Complicated by Diabetes
Continuous glucose monitoring (CGM) methods provide details of magnitude and duration of glucose fluctuations, giving a unique insight on daily blood sugar control.
- Conditions
- Gestational Diabetes, Continuous Glucose Monitoring, Glycemic Variability
- Trial name
- NCT01883622
- Where
- 3 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Padova
Stress, Psychological
Comparative Intervention Study of Stress Reduction in Corporate Health Management
Aim of the study is the evaluation of the effects (psychological and physiological) of an hrv-biofeedback training, a mindfulness training and a combination of both training methods for stress reduction.
- Trial name
- NCT02709551
- Testing
- HRV_Bfb, MBI, MBI_HRV_Bfb
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Extravascular Lung Water
Role of Lung Ultrasonography in Detecting Extravascular Lung Water in Major Oncosurgeries
During major surgeries optimal intravenous fluid administration is essential , conventional method may cause fluid overload , increased extravascular Lung water can lead to postoperative cardio-respiratory complications , this…
- Trial name
- LUS EVLW (NCT04659681)
- Testing
- PVI Guided fluid management during surgery for (PVI<12) colloid bolus will be given ., CVP Guided Fluid management during surgery for CVP<10 cms H2O colloid bolus will be given
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Post-spinal Hypotension
Variability of Perfusion Index to Predict Hypotension
About one-third of deliveries are performed by cesarean section, and this rate is increasing. The standard anesthetic technique for this procedure is spinal anesthesia (SA), which is associated with hypotension in nearly 70% of…
- Trial name
- IP-HYPO (NCT06769750)
- Testing
- leg-lift maneuver
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Major Depressive Disorder
Single Session of tACS in a Depressive Episode
Purpose: Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on healthy participants and participants with mood disorders.
- Conditions
- Depression, Major Depressive Disorder, Premenstrual Dysphoric Disorder, Depressive Episode
- Trial name
- SSDE (NCT03449979)
- Testing
- XCSITE100 Stimulator tACS
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypertension, Insulin Resistance Syndrome
Cf-PWV and TyG Index Study
This study aims to investigate how metabolic health is related to arterial stiffness and daily blood pressure patterns. High blood pressure is one of the leading causes of heart disease worldwide, but cardiovascular risk is not…
- Conditions
- Hypertension, Insulin Resistance Syndrome, Arterial Stiffness, Cardiovascular Risk
- Trial name
- RIGID-TyG (NCT07589374)
- Where
- Brazil
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Heart Rate Variability
Heart Rate Variability and Emotion Regulation
Previous research suggests that heart rate variability (HRV) biofeedback aimed at increasing HRV can reduce anxiety and stress. However, some mental quiescence practices that reduce HRV during the practice sessions also lead to…
- Trial name
- HRV-ER (NCT03458910)
- Testing
- HRV training
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cardiac Diseases
Ephrin B1 Regulation in Human Right Appendage
Background : Ephrin-B1 is part of the large Eph/Ephrin system which is involved in cell-cell comunication. The role of Ephrin-B1 has scarcely been studied in adulthood.
- Trial name
- REBORD (NCT01080781)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Sleep Variability
The Effects of Sleep Variability in Youth
Daily sleep variability is prevalent in the young populations, yet its effects remain less clear. The experimental study aims to examine the impacts of intraindividual daily sleep variability on sleep characteristics…
- Trial name
- NCT04263428
- Testing
- Irregular sleep
- Where
- Hong Kong
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Major Depressive Disorder
LEPR Polymorphism Weight Gain by Mirtazapine in Late Life Depression
Patients with an episode of depression in late life prescribed mirtazapine recruited from a clinical sample will be monitored for weight and receive a blood test during their usual course of treatment to determine polymorphisms…
- Trial name
- NCT01601002
- Testing
- Mirtazapine
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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