Clinical trials: Variability
Hyperglycemia, Hypoglycemia
Pilot Study of Intensive Care Unit Continuous Glucose Monitoring
The investigators believe that there remains a gap in implementing insulin infusions in critically ill patients to maximize the benefit and minimize adverse events like episodes of hypoglycemia.
- Trial name
- NCT01301053
- Testing
- Current UVA intensive care insulin protocol, Current UVA intensive care insulin protocol with "brakes"
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Gonarthrosis, Knee Osteoarthritis
Efficacy of Craniosacral Therapy in Patients With Gonarthrosis
This randomized controlled trial was designed to investigate the effects of craniosacral therapy on pain, heart rate variability, joint stiffness, physical function, quality of life, body image, kinesiophobia, and dynamic balance…
- Trial name
- NCT07372534
- Testing
- Craniosacral Therapy, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara Yildirim Beyazıt University
Stroke, Caregiver Burnout
Effectiveness of Mindfulness After a Stroke
Mindfulness is promising for individuals with neurological disorders and caregivers to improve psychological well-being. This study aims to determine the extent to which a 3-week online mindfulness intervention will improve…
- Trial name
- NCT05029193
- Testing
- Langerian mindfulness
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Southern California
Hearing Loss, Presbycusis
Variability In Hearing Aid Outcomes In Older Adults
The goal of this project is to find out if the way a hearing aid processes a sound signal should be determined in part by an individual's cognitive characteristics.
- Trial name
- NCT02448706
- Testing
- Hearing Aid Fitting A, Hearing Aid Fitting B
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Northwestern University
Insomnia, Health Adult Subjects
Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
The goal of this clinical trial is to learn if yoga works to improve sleep and heart health in adults with and without insomnia disorder.
- Conditions
- Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
- Trial name
- NCT07638267
- Testing
- Vinyasa yoga, Gentle yoga, Non-active control
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Caitlin Cheruka
Type 2 Diabetes
FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR)
Results of recent studies using standard long and short acting insulin therapy (Basal - Bolus or BBI) in type 2 diabetes mellitus (T2DM) have not shown benefits to lower risks for heart attacks, strokes, or eye, nerve and kidney…
- Trial name
- FLAT-SUGAR (NCT01524705)
- Testing
- Insulin Glargine, Metformin, Prandial insulin
- Where
- 12 sites in United States
- Volunteers
- 102 people
- Sponsor
- University of Washington
Basal Cell Carcinoma
Clinical Diagnosis of Basal Cell Carcinoma Subtype
Skin cancer is the most common cancer in Caucasians. Basal cell carcinoma (BCC) is the most frequent skin cancer with around 44.000 new tumours per year in the Netherlands, and its incidence is still rising.
- Trial name
- NCT01370824
- Testing
- Punch biopsy, Surgical excision
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Type 2
Acute Effects of Inspiratory Muscle Exercise on Glucose Level and Glucose Variability in Patients With Type 2 Diabetes.
Type 2 diabetes is associated with respiratory muscle weakness and autonomic neuropathy. The exercise of inspiratory muscles has been investigating in various clinical situations and may cause similar benefits as the conventional…
- Trial name
- NCT02292810
- Testing
- Inspiratory muscle exercise
- Volunteers
- 14 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 2 of 7)
NOTE: This is the second of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882529
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy Volunteers, PHYSIOLOGICAL PHENOMENA
Study on Biomagnetic and Physiological Signals During Reiki Practice in Healthy Volunteers.
This study evaluates whether the practice of laying on of hands (Reiki) produces detectable biomagnetic and physiological modulations proximate to the human body in healthy volunteers.
- Conditions
- Healthy Volunteers, PHYSIOLOGICAL PHENOMENA, Biomagnetic and Physiological Effects of Laying on of Hands
- Trial name
- NCT07871981
- Testing
- Reiki Therapy, Mock Hand Placement
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Anhembi Morumbi University
Maraviroc Concentrations in Semen
Concentrations of Maraviroc in the Semen of HIV-Infected Men
The objective of this study is to determine if concentrations of maraviroc in semen exceed the 50% and 95% inhibitory concentrations of HIV during the dose interval.
- Trial name
- NCT01009034 (NCT01009034)
- Testing
- Measuring semen samples
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Canadian Immunodeficiency Research Collaborative
Resistant Hypertension, Secondary Hypertension
Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization
To explore the relationship between perioperative blood pressure and catecholamine concentrations in adrenal venous blood and peripheral venous blood in hypertensive patients with primary aldosteronism (PA) who underwent…
- Conditions
- Resistant Hypertension, Secondary Hypertension, Secondary Hypertension to Endocrine Disorders, Primary Aldosteronism
- Trial name
- NCT06228677
- Testing
- Selective adrenal artery embolization
- Where
- China
- Volunteers
- 196 people
- Sponsor
- First Affiliated Hospital of Chengdu Medical College
Exercise-Induced Fatigue
Muscle Oxygenation and Autonomic Recovery After Repeated Sprint in Competitive Soccer Players
This study evaluates the acute and short-term recovery responses to repeated sprint exercise in competitive male soccer players.
- Trial name
- NCT07742163
- Testing
- 8 x 30 m Repeated Sprint Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Overactive Bladder
Evaluation of Autonomic System Before and After Anticholinergic Treatment in Women With Overactive Bladder
The aim of the study is to evaluate changes in autonomic nervous system following treatment with anticholinergic medication for OAB symptoms.
- Trial name
- NCT01409512
- Testing
- ECG recording
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Subluxation
Simulated vs Genuine Manual Chiropractic Adjustments
Our primary aim with this trial is to measure participant blinding following two simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments to assess if participants are able to identify…
- Trial name
- SHA (NCT06931600)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Life University
Heart Failure
Heart Failure and Sleep Disordered Breathing
The purpose of this study is to analyze and summarize the characteristics of arrhythmia and heart rate variability of Chinese patients with three different types of heart failure combined with sleep disordered breathing based on…
- Trial name
- NCT05892172
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yihui Kong
Low Back Pain, Pregnancy
Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects
The purpose of this study is to determine to what extent and by what physiological mechanisms Osteopathic Manipulative Medicine (OMM) affects selected conditions related to pregnancy, labor and delivery.
- Trial name
- NCT00426244
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Patients Without a Medical History of Thrombosis or Hemorrhage, Hemophilic Patient
Evaluation of the Inter-center Variability of the Measurement of Thrombin Generation by the ST Genesia System
The thrombin generation test is a global test for the study of coagulation that allows the fine study of the balance between procoagulant and anticoagulant factors.
- Conditions
- Patients Without a Medical History of Thrombosis or Hemorrhage, Hemophilic Patient, Patient With FV Leiden Mutation, Patient With Cirrhosis
- Trial name
- EVIGE (NCT05422157)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Clermont-Ferrand
Craniosynostoses, Hypovolemia
Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)
Hemodynamic evaluation during pediatric anesthesia is essential to care management. Intraoperative cardiovascular instability is frequent in major surgeries, and appropriate monitoring is necessary to ensure safe anesthetic…
- Conditions
- Craniosynostoses, Hypovolemia, Hemorrhage, Hemodynamic Instability
- Trial name
- CRASY-PRAM (NCT06263075)
- Testing
- Intraoperative monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Transesophageal Echocardiography
The Effect of Sedation During Transesophageal Echocardiography on Heart Rate Variability
There is no ideal sedation technique that can be used during Transesophageal Echocardiography (TEE), and the data concerning the effects of available sedation techniques on Heart Rate Variability (HRV) are limited.
- Trial name
- NCT01444976
- Testing
- local anesthesia, hypnosis, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
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