Clinical trials: Variability
Diabetes Mellitus, Type 2
Insulin Glargine in Type 2 Diabetes Mellitus
Primary objective: To evaluate in explorative manner the fasting blood glucose (FBG) coefficient of variability (CV)calculated on SMBG values (SMBG : Self-Monitoring of Blood Glucose).
- Trial name
- NCT00272077
- Testing
- Insuline glargine
- Sponsor
- Sanofi
Narcolepsy, Cataplexy
Cardiovascular Variability and Heart Rate Arousal Response in Idiopathic Hypersomnia
Autonomic nervous system dysfunction has been described in narcolepsy with cataplexy affecting the sympathetic function. In this study the investigators analyzed whether altered diurnal and nocturnal cardiovascular control is…
- Trial name
- NCT02913651
- Testing
- Polysomnography
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hematopoietic Stem Cell Transplantation, Bone Marrow Transplant
The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients
Patients undergoing hematopoietic stem cell transplantation (HCT) often continue to experience anxiety, depression, isolation, and other psychosocial distress due to the severe nature of the transplant experience.
- Conditions
- Hematopoietic Stem Cell Transplantation, Bone Marrow Transplant, Heart Rate Variability, Autonomic Nervous System
- Trial name
- NCT04275830
- Testing
- Baseline Surveys, Heart rate variability biofeedback, Heart rate variability waitlist and Digital storytelling Control intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Arizona State University
Subarachnoid Hemorrhage, Aneurysmal
Artificial Intelligence in Subarachnoid Hemorrhage
The overall aim of this study is to, with the help of computer/data scientist and machine learning processes, analyse collected heart rate variability data in order to evaluate whether specific patterns could be found in patients…
- Trial name
- AISAH (NCT04415736)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Göteborg University
Polycystic Ovary Syndrome
Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome
Hypothesis The overall hypothesis is that non-obese (BMI <30) women with PCOS have high luteinising hormone (LH) and cortisol pulse frequency and amplitude and that repeated low-frequency EA restore these alterations and induce…
- Trial name
- PCOSLFEA (NCT00921492)
- Testing
- Low-frequency electro-acupuncture (EA), Meeting a therapist - attention control
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Göteborg University
Type 1 Diabetes, Type 2 Diabetes
Closed Loop Glucose Control in a Simulated ICU Setting
This is a proof of concept safety study of a rule-based closed loop glucose control system designed for use in the intensive care unit setting.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Stress Induced Hyperglycemia
- Trial name
- NCT07646067
- Testing
- FUSION closed loop glucose control system
- Volunteers
- 6 people
- Sponsor
- Ideal Medical Technologies
Water Stress, Body Water Dehydration
Influence of Osmotic Stimulation of Vasopressin on Autonomic Function
The regulation of total body water that defines human hydration status is a complex and dynamic process. Current methods of assessing hydration status (e.g.
- Trial name
- NCT04233606
- Testing
- Hypertonic Saline, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Acute Coronary Syndrome, Continuous Glucose Measurement
Predictive Value of Glycemic Parameters Measured With the FSL Pro iQ During ACS
Disorders of glycemic regulation are common in patients hospitalized for acute coronary syndrome (ACS). Abnormal glycaemia is observed in 50% of cases, in 30-40% diabetes, and in 25-35% fasting hyperglycaemia or glucose…
- Conditions
- Acute Coronary Syndrome, Continuous Glucose Measurement, Glycemic Variability, Cardiovascular Event
- Trial name
- FREESCA (NCT06014112)
- Testing
- Freestyle Libre Pro iQ
- Where
- 9 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease
The Role of Vitamin D in Immune Function in Patients With Chronic Kidney Disease (CKD) Stages 3 and 4.
Patients with chronic kidney disease (CKD) are commonly deficient in vitamin D, with low levels of both calcidiol (25 hydroxy vitamin D) and calcitriol (1,25-hydroxy vitamin D).
- Trial name
- NCT00749736
- Testing
- cholecalciferol, doxercalciferol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Prostate Cancer
PROstaTe Cancer - Exercise-STudy (PRO-TEST)
Background and purpose: The purpose of this study is to investigate the effect of exercise on intratumoral natural killer (NK)-cell variability in patients with localized prostate cancer undergoing radical prostatectomy.
- Trial name
- PRO-TEST (NCT02954783)
- Testing
- High Intensity Interval Training, Usual Care Observational Control
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Widespread Pain, Fibromyalgia
Body Versus Machine: Deep Breathing Versus Vagus Stimulation for the Treatment of Fibromyalgia
This randomized controlled trial aims to compare the efficacy of two vagal nerve innervation treatments, motivational nondirective resonance breathing and transcutaneous vagus nerve stimulation, on heart rate variability and pain…
- Trial name
- NCT03180554
- Testing
- Transcutaneous Vagal Nerve Stimulation (tVNS), Motivational nondirective resonance breathing (MNRB)
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Charles Ethan Paccione, M.S., M.A.
Cognitive Reserve, BIS
Use of Sevoflurane to Test Concept of Cognitive Reserve
Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia.
- Trial name
- NCT06490588
- Testing
- sevoflurane
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Los Angeles General Medical Center
Step Time and Length, Symmetry
The Contribution of Heels for Walking Quality Among Children With Muscular Dystrophy
During the stand phase the DMD foot is too plantarflexed in addition patients adopt a higher flexion and abduction of the hip in order to advance the swinging limb.
- Conditions
- Step Time and Length, Symmetry, Step Time and Length Variability, Heart Rate
- Trial name
- NCT01638169
- Testing
- adding a heel
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Pediatric Anxiety
Non-Wearable Audiovisual Distraction for Children's Medical Anxiety in the ED
Pediatric emergency department (ED) visits often cause significant anxiety and stress for young patients due to unfamiliar environments and invasive medical procedures.
- Trial name
- NCT07761637
- Testing
- Non-Wearable Audiovisual Distraction, Routine ED Care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Prostate Infections
Impact of Antibiotic Treatment on Prostate-Specific Antigen (PSA) Variability
Ciprofloxacin hydrochloride has been approved by the Food and Drug Administration (FDA) for the treatment of mild to moderate infections, including prostate infections.
- Trial name
- NCT00596453
- Testing
- Ciprofloxacin hydrochloride
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Johns Hopkins University
Autism, Autism Spectrum Disorder
Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism
This study examines the impact of guided breathing exercises on stress and heart rate variability (HRV) in autistic young adults.
- Trial name
- PEACE-A (NCT07238153)
- Testing
- Guided breathing exercise - SPB, Guided breathing exercise - HRV-BF
- Where
- 2 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obstructive Sleep Apnea Syndromes
Interest of Treatment of Obstructive Sleep Apnea Syndrome by Constant CPAP and Auto CPAP
The investigators propose a multicentric controlled randomized trial whose goal is to evaluate the possibility of a prediction of the efficiency of APAP (automatic continuous positive airway pressure) and constant CPAP (constant…
- Trial name
- PREDIVARIUS (NCT02749812)
- Testing
- Constant Continuous Positive Airway Pressure, Automatic continuous Positive Airway Pressure
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Cardiomyopathy, Dilated
Variability of Ventricular Mass, Volume, & Ejection Fraction in Pediatric Cardiomyopathy Patients-Pediatric Heart Network
This observational study will provide data (variations in ventricular size and function) that are essential to designing and conducting clinical trials.
- Trial name
- VVV (NCT00123071)
- Where
- 8 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Carelon Research
Sleep Quality
Effects of Binaural Beat Music on Elderly Sleep
Background: Older people in long-term care institutions often have poor sleep quality and depression, which may negatively affect their health and welfare. Binaural beat music (BBM) has been proposed as a possible intervention.
- Trial name
- NCT05975853
- Testing
- Binaural beat music group (BBM group), Control group
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Cheng Kung University
Persistent Pain After Open Inguinal Herniotomy
Variability in Thermal Thresholds in Patients With Persistent Pain After Open Inguinal Herniotomy
The study will investigate the test-retest variability of thermal thresholds in patients with persistent pain after open inguinal herniotomy.
- Trial name
- NCT01768130
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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