Clinical trials: Variability
Liver Transplantation (LT)
Intraoperative Glycemic Variability and Infectious Complications After Liver Transplantation
This study aims to evaluate whether intraoperative glycemic variability (GV) is independently associated with the risk of infectious complications within 30 days after elective liver transplantation.
- Trial name
- SUGAR-LT (NCT07786857)
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Healthy
The Effects of Single-Pulse Transcranial Magnetic Stimulation on the Autonomic Nervous System in Healthy Adults
The purpose of this study is to determine the effects of TMS on the ANS. The investigator will determine whether single-pulse TMS of the primary motor cortex in the dominant hemisphere in healthy, young adults will affect 1)…
- Trial name
- NCT02833220
- Testing
- Single-Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Sleep, Sleep Restriction
Performance, Mood, and Brain and Metabolic Functions During Different Sleep Schedules
This proposed project will investigate whether a variable or a stable sleep schedule will be more effective in minimizing neurobehavioural and metabolic deficits when total sleep opportunity across two weeks is below the…
- Trial name
- STAVAR (NCT04731662)
- Testing
- Short sleep, Variable short sleep
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Head and Neck Cancers
SOMESThesia and ALIMentation
Cancer patients are at high risk for undernutrition. A study with head and neck cancer patients showed that 50% suffered from undernutrition (Prevost et al., 2014).
- Trial name
- SOMEST'ALIM (NCT05272917)
- Testing
- Sensorial tests, food preferences questionnaires
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Glucose Tolerance, HRV
Effect of Hot Water Immersion on Heart Rate Variability and Glucose
Heat therapy has been shown to reduce risk of various diseases, including heart disease, alzheimers, and pneumonia, as well as all-cause mortality .
- Trial name
- HWI (NCT06193291)
- Testing
- Feet heating, Calf heating
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Bladder Disorder, Neurogenic
Heart Rate Variability (HRV) in Patients With Neurogenic Detrusor Overactivity (NDO) Before and After Botulinum Neurotoxin Type A (BoNT/A) Intradetrusor Injections
Heart rate variability (HRV) is an important indicator of cardiac autonomic function and predictor of cardiac mortality and of all-cause mortality.
- Trial name
- HRV/Botox (NCT01337024)
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Pelvic Fractures, Fragility Fractures of the Pelvis (FFP)
Assessment of Treatment Variability for Pelvic Ring Fragility Fractures
Fragility fractures of the pelvic ring are a common injury associated with poor patient outcomes and high healthcare costs. Management of these injuries is evolving with increasing frequency of operative stabilization of the…
- Trial name
- Pelvis ATV (NCT07351123)
- Testing
- Surgical stabilization of pelvic fracture, Closed treatment of pelvic fracture
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Maryland, Baltimore
Diabetes Mellitus, Type 2
Cognitive Training for Diabetes Self-Management
The overall objective of this study is to determine the effects of a comprehensive cognitive rehabilitation intervention on biological, cognitive, and diabetes self-management outcomes.
- Trial name
- NCT04831775
- Testing
- Memory, Attention, and Problem Solving Skills for Diabetes, Brain Games
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Tooth Abnormalities, Tooth Abnormality
Analysis of Tooth Root Number
The aim of this cross-sectional study is to assess the number of roots in permanent teeth. For this reason, researchers will conduct an analysis of CBCT scans.
- Conditions
- Tooth Abnormalities, Tooth Abnormality, Tooth Anatomy, Tooth Development Disorder
- Trial name
- NCT07170956
- Where
- Poland
- Volunteers
- 4,000 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Binge-Eating Disorder
Binges and Neural Variability
People who suffer from binge eating disorder experience recurrent episodes of binge eating.During these episodes, they consume an unusually large amount of food in a short amount of time and experience loss of control over…
- Trial name
- BEDVAR (NCT04184856)
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Knee Osteoarthritis, Chronic Pain
Arthritis Ease Study
The goal of this clinical trial is to test using a pain and anxiety reduction phone application in older adults with knee osteoarthritis and chronic pain. The main questions it seeks to answer are: 1.
- Conditions
- Knee Osteoarthritis, Chronic Pain, Kinesiophobia
- Trial name
- NCT05721352
- Testing
- Virtual Reality Nature scene plus heart rate variability biofeedback phone application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Arizona State University
Obesity, Heart Rate Variability
Obesity and Bariatric Surgery According to a Biopsychosocial Perspective.
The main goal of this prospective longitudinal observational study is to investigate the psychophysiological indicators by analyzing HRV, blood pressure, symptoms of anxiety and depression, eating behavior and quality of life…
- Conditions
- Obesity, Heart Rate Variability, Anxiety Disorders, Depression
- Trial name
- NCT05950698
- Testing
- Holter Faros 360° EKG (Bittium Corporation), Beck Depression Inventory (BDI), Hospital Anxiety and Depression Scales - HADS
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Rio de Janeiro State University
Cardiovascular Diseases, Myocardial Ischemia
Cohort Study of Heart Rate Variability
To examine factors affecting heart rate variability (HRV) and the role of HRV in heart disease. Specifically, to examine the role of HRV: as a predictor of fatal and nonfatal ischemic heart disease over a six year follow-up of…
- Conditions
- Cardiovascular Diseases, Myocardial Ischemia, Carotid Stenosis, Hypertension
- Trial name
- NCT00005399
- Testing
- No interventions
- Volunteers
- 111,654 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Active Athletes
Effect of Hydrogen-rich Water During Tapering on Recovery After Functional Overreaching in Basketball Players
The goal of this clinical trial is to evaluate whether hydrogen-rich water supplementation during tapering improves recovery after functional overreaching in competitive male basketball players aged 18-35 years.
- Trial name
- NCT07714057
- Testing
- Hydrogen-rich water
- Where
- Czechia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Palacky University
Sedentary Behavior
Virtual Reality Training for Heart Rate Variability and Recovery Heart Rate
To determine effects of VR training on Heart Rate Variability (HRV), Recovery Heart rate (RHR), Rate Pressure Product (RPP) and Rate of Perceived Exertion (RPE) in sedentary Individuals.
- Trial name
- NCT06708364
- Testing
- Virtual Reality Training, Cycle Ergometer
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Type 1 Diabetes Mellitus
A Cognitive Behavioral Therapy (CBT) Intervention to Reduce Fear of Hypoglycemia in Type 1 Diabetes
All persons with type 1 diabetes are at risk for developing hypoglycemia (low blood sugar). This is a life-threatening condition that leads to profound fear of hypoglycemia and reduced quality of life.
- Trial name
- CBT (NCT03549104)
- Testing
- Fear Reduction Intervention, Attention Control
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Illinois Chicago
Mitral Regurgitation
Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair
Transcatheter mitral valve repair in the form of MitraClip® is a safe and effective alternative to surgical mitral valve repair/replacement in patients with high operative morbidity and mortality risk.
- Trial name
- NCT03993938
- Testing
- PVI measurement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Henry Ford Health System
Critical Illness
Glycemic Index Variation During Low-carbohydrate Enteral Formula With and Without Fructose in Critically Ill Patients
Hyperglycemia is a known risk factor for mortality in critically ill patients. Most of these patients receive enteral feeding. There is controversy about ideal carbohydrate composition of these diets.
- Trial name
- NCT03003507
- Testing
- Enteral Formula With Fructose, Enteral Formula Without Fructose
- Volunteers
- 25 people
- Sponsor
- Hospital Moinhos de Vento
Healthy
Effects of a Novel Supplement on Glycemic Variability Measured by Continuous Glucose Monitoring
This is a two-cohort, crossover pilot study to determine interstitial glucose levels coincident with the consumption of a novel carbohydrate blocking supplement.
- Trial name
- NCT05832463
- Testing
- Carbohydrate blocking supplement (CBS)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
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