Clinical trials: Variability
Ischemic Preconditioning
Effects of Ischemic Preconditioning on Conditioned Pain Modulation and Heart Rate Variability in Knee Osteoarthritis
Introduction: Musculoskeletal disorders have affected approximately 1.3 billion people worldwide. Evidence shows that chronic diseases and musculoskeletal conditions often occur together, and among them it is estimated that more…
- Trial name
- NCT05059652
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Paulista University
Lung Cancer
Short-term Effects of Osteopathic Manipulations on Heart Rate Variability in Lung Cancer Patients - A Randomized Pilot Study
In France, the number of new cancer cases each year is rising steadily, while the number of deaths, although falling, is still around 157,000, including 23,000 from lung cancer alone.
- Trial name
- NCT06822348
- Testing
- Osteopathic treatment, Quality of life assessment, Anxiety assessment
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Heat Stress
Heat Stress Exposure Among Low-Income Residents in Bangladesh and Evaluation of Indoor Interventions
The goal of this clinical trial is to learn if infrastructure and equipment installed to cool homes reduce adverse health outcomes.
- Trial name
- NCT06979258
- Testing
- Cooling intervention
- Where
- Bangladesh
- Volunteers
- 1,539 people
- Sponsor
- University of California, Berkeley
Cardiovascular Diseases, Prevention
Acute Effects of Beet Extract on Autonomic and Cardiovascular Recovery After Exercise
Dietary NO3 is found in high concentrations in green leafy vegetables and beets. Studies weighing the action of NO3 for ergogenic purposes have found metabolic improvement in skeletal muscle during exercise in hypoxia, lowering…
- Trial name
- NCT04094233
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Long COVID, Heart Rate Variability (HRV)
Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid
Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems.
- Conditions
- Long COVID, Heart Rate Variability (HRV), Cardiac Biomarkers, Inflammatory Biomarkers
- Trial name
- LongCovidRehab (NCT07046208)
- Testing
- physiothreapy protocol
- Volunteers
- 58 people
- Sponsor
- Universidade do Estado do Pará
Ischemic Stroke
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC) initiates autonomic nervous system response and affects the prognosis in patients with acute ischemic stroke.
- Trial name
- IRAS (NCT02777099)
- Testing
- remote ischemic postconditioning
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Postoperative Complication
Goal Directed Fluid Management Based on Non-invasive Monitoring
The purpose of this study is to evaluate whether goal directed fluid management using respiratory variations in the oxygen saturation by pulse oximetry (SpO2) waveform has potential to decrease postoperative complications and…
- Trial name
- NCT01883752
- Testing
- Goal-directed Therapy group
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- University of California, Irvine
Diabetic Cardiovascular Autonomic Neuropathy, Type 2 Diabetes Mellitus
Acupuncture Plus Mecobalamin for Diabetic Cardiac Autonomic Neuropathy
The goal of this clinical trial is to learn whether acupuncture can improve damage to the nerves that control the heart (cardiac autonomic neuropathy) in adults with type 2 diabetes.
- Conditions
- Diabetic Cardiovascular Autonomic Neuropathy, Type 2 Diabetes Mellitus, Diabetic Neuropathies
- Trial name
- NCT07907536
- Testing
- Acupuncture, Mecobalamin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Neurophysiological Mechanisms Underlying Spinal Manipulation
The Effects of Mid-thoracic Manipulation on Heart Rate Variability.
The topic of spinal manipulation (SM) has been a source of increasing research over the past decade. Research has focused primarily upon the functional and clinical outcomes associated with SM.
- Trial name
- NCT02379871
- Testing
- Experimental Group
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mount St. Mary's College, Los Angeles, CA
Irritable Bowel Syndrome (IBS)
Exercise and Vagus Nerve Stimulation in IBS
The aim of the study was to consider the possible role of exercise and vagus nerve on bowel functionality in chronic IBS and to demonstrate that exercise and transcutaneous auricular stimulation of the vagus nerve can reduce…
- Trial name
- NCT06769516
- Testing
- Auricular Vagus Nerve Stimulation (aVNS), Aerobic Exercise Therapy, Low FODMAP Diet Intervention
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Bahçeşehir University
Hematopoietic Stem Cell Transplant
Effects of Compassion Training to Patients Undergoing HSCT on Biological and Psychosocial Parameters
The hematopoietic stem cell transplant (HSCT) experience is emotionally and physically stressful for cancer patients who undergo this procedure.
- Trial name
- NCT03737084
- Testing
- CBCT Intervention
- Where
- 2 sites in Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Spinal Cord Injury
Cardiovascular Autonomic Function After Resistance Training
The purpose of this clinical trial is to evaluate whether an 8-week upper-limb resistance training program improves cardiovascular autonomic function in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07725952
- Testing
- Upper-Limb Resistance Training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Craniosynostosis
Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery
This prospective observational study aims to evaluate the role of pleth variability index (PVI) and perfusion index (PI) monitoring in intraoperative hemodynamic control among pediatric patients undergoing craniosynostosis…
- Trial name
- PVI-CRANIO (NCT07657598)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Muzaffer GENCER
Diabetes Mellitus, Covid19
Continuous Glucose Monitorization in Hospitalized Patients With COVID-19
DM2 is a major comorbidity of COVID-19. It has been observed that subjects with DM2 require more medical interventions, have a significantly higher mortality (7.8% versus 2.7%) and injuries of multiple organs that the individuals…
- Trial name
- NCT05096858
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Acute Myeloid Leukemia (AML)
Feasibility Pilot Exploring Variability in Biomarkers and PROs in AML
This research study is being conducted to help understand how the symptoms during treatment for acute myeloid leukemia (AML) may be affected by metabolism and how best to study this association.
- Trial name
- NCT04908852
- Testing
- Blood Sample Collection - Observational Study, Symptom questionnaires - Observational Study
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-3
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01045811
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Bone and Joint Infection, Patient Treated by Daptomycin
Pharmacokinetic Variability of Daptomycin During Prolonged Therapy for Bone and Joint Infections
Daptomycin is a cyclic lipopeptide that has been proposed as an alternative therapeutic option in patients with prosthetic joint infection caused by Staphylococcus or Enterococcus species in the latest Infectious Diseases Society…
- Trial name
- NCT03209921
- Volunteers
- 23 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Failure, Intensive Care Pediatric
The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubation Process.
The extubation process is critical to the future health outcomes of the pediatric patient because it tests the ability of the respiratory system to function without the support of mechanical ventilation.
- Trial name
- NCT06591533
- Testing
- Music therapy + standard care, Standard Care (in control arm)
- Where
- 2 sites in Colombia
- Volunteers
- 82 people
- Sponsor
- Claudia Aristizábal
Opioid Induced Motor Disturbances
Opioid Induced Gait Variability
While the analgesic effects of opioids are well known, evidence suggest that there are differences in the adverse dizziness of the different opioid types, which may influence the gait function differently.
- Trial name
- NCT03121547
- Testing
- Tapentadol 50 mg Oral Tablet, Tramadol Hydrochloride 100 mg Extended Release Oral Tablet
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Hip Fracture
Association Between HRV and Postoperative Mortality in Hip Fracture Patients
165 patients admitted to two hospitals were included and short-time HRV measurements were obtained. Mortality data were gathered from the Norwegian central address register.
- Trial name
- HRVHip (NCT03426501)
- Volunteers
- 165 people
- Sponsor
- Vestre Viken Hospital Trust
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