Clinical trials: Variability
Hemolysis, Diagnostic Errors
Pneumatic Tube System Versus Personnel Transport and the Hemolysis Index of Emergency Department Blood Samples: A Randomized, Split-Sample, Single-Blind Trial
Hemolysis is the most common pre-analytical error in emergency department (ED) laboratory specimens and can lead to false elevation of intracellular analytes (potassium, LDH, AST, hemoglobin), resulting in misdiagnosis and…
- Conditions
- Hemolysis, Diagnostic Errors, Blood Specimen Collection
- Trial name
- PTS-HEMO-ED (NCT07755007)
- Testing
- Pneumatic Tube System Transport, Manual Personnel Transport
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Ventilator Lung; Newborn
NIPE as an Indicator of Pain in Sedated/Ventilated Patient Under 3 Years-old Hospitalized in Intensive Care Unit
The main objective is to assess correlation between Newborn Infant Parasympathetic Index values and external evaluation by Comfort Behaviour Scale during painful medical cares in sedated intubated children admitted in pediatric…
- Trial name
- NIPE (NCT04195672)
- Testing
- NIPE (MDoloris®) and CBS values
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Type 2 Diabetes, A1C Variability
Is Carotid Intima-media Thickness Affected by A1C Variability?
This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.
- Trial name
- NCT00842972
- Sponsor
- Yonsei University
Emergency Department Triage, Non-invasive Hemodynamic
Identification of High-Risk Patients at Admission to an Emergency Department by Non-Invasive Hemodynamics
The goal of this study is to evaluate the prognostic values of non-invasive hemodynamic parameteres in relation to 30-day mortality and/or acute deterioration in patients who are admitted acutely to the department of emergency…
- Trial name
- NCT03934775
- Testing
- Finapres Nova
- Where
- Denmark
- Volunteers
- 942 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Insomnia, Insomnia Chronic
Efficacy and Accuracy of an AI-Driven Sleep Earbud for Chronic Insomnia
This study evaluates a new smart sleep earbud designed to help adults suffering from chronic insomnia. The device uses artificial intelligence (AI) to track a user's real-time heart rate and movement through the ear canal…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorders, Sleep Wake Disorders
- Trial name
- NCT07744581
- Testing
- AI-driven Neuromodulation Music (NeuroRhythm)
- Where
- 2 sites in China
- Volunteers
- 25 people
- Sponsor
- The Chinese University of Hong Kong, Shenzhen
Diabetes Mellitus, Non-Insulin-Dependent
Effects of Vildagliptine and Glimepiride on Glucose Variability
The purpose of this study is to analyze the differences of blood sugar level and glycemic variability between sulfonylurea and DPP-4 inhibitor groups applying CGMS for a chosen number of type 2 DM patients.
- Trial name
- NCT01812122
- Testing
- Glimepiride, Vildagliptin
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus
Potential Correlation Between Heart Rate Variability With Cardiovascular Risk at Different Stages of Metabolic Syndrome
The study aims to assess the beat-to-beat Heart rate variability (HRV) in different stages of metabolic diseases, including pre-diabetic and diabetic patients, compared to non-diabetic individuals.
- Trial name
- NCT06305195
- Testing
- heart rate variability test
- Where
- Egypt
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hypovolemia, Somatic Pain
Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
The purpose of this study is to determine whether the value of analgesia nociception index (ANI) is influenced by variations of systemic venous return (cardiac preload) under general anaesthesia.
- Trial name
- NCT02193412
- Testing
- noxious stimulus, change in operating table slope: head-down tilt position, change in operating table slope: head-up tilt position
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Cornea, Sense Loss; Cornea
Investigation in Corneal Sensation and Contact Lens Wear
The aim is to find out more about how corneal sensory fibres react to different types of stimuli (liquid / tactile / nylon thread) and how this can be consciously perceived by the individual.
- Trial name
- NCT04804592
- Testing
- Tactile Esthesiometer Prototype, Liquid Jet Esthesiometer Prototype, Cochet Bonnet esthesiometer
- Where
- Switzerland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Obstructive Sleep Apnea
Polysomnography and Heart Rate Indexes in Obstructive Sleep Apnea
The purpose of this study is to evaluate the diagnostic accuracy of polysomnography indexes for diagnosis of sleep apnea in human subjects obstructive sleep apnea (OSA).
- Trial name
- NCT02044900
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Ovidiu Constantin Baltatu
Cardiac Surgery, Coronary Artery Bypass Graft
Micro- and Macro-Circulation in Cardiac Surgery Patients
The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major…
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Graft, Surgical Aortic Valve Replacement
- Trial name
- MiMaC (NCT05706545)
- Testing
- Acquisition of cardiovascular signals and microcirculation sidestream darkfield images
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Oily Skin
Exploratory Study of Intra and Inter-subject Variability in Sebum Excretion Rate
The purpose of this study is to analyze the relationship between sebum excretion rate and the following factors: Hormone levels (testosterone, dehydroepiandrosterone sulfate) Expression of 5-α-reductase type 1 (a protein in…
- Trial name
- NCT01640028
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Psychological Stress
Horse-assisted Intervention, Heart Rate Variability & Stress
In this study, the effects of an animal-assisted intervention on people with increased stress levels are investigated. The data collected will be compared with those of participants with high stress levels but without…
- Trial name
- NCT05703165
- Testing
- animal-assisted intervention, watching the countryside
- Where
- Austria
- Volunteers
- 123 people
- Sponsor
- Medical University of Graz
Posttraumatic Stress Disorder
Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
The goal of this observational sub-study is to provide information on how MDMA-assisted therapy affects the brain and body of people with chronic PTSD.
- Trial name
- NCT02102802
- Testing
- Midomafetamine, Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Resilient Pharmaceuticals
Diet Habits, Athlete
Legume-Enriched Mediterranean Diet and Cellular Hydration in Competitive Swimmers
This study investigates whether increasing legume consumption within a Mediterranean diet framework improves cellular hydration, autonomic regulation, and functional performance in competitive swimmers.
- Trial name
- LEGUMES-SWIM (NCT07315529)
- Testing
- Legume-enriched Mediterranean diet
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- San Raffaele Telematic University
Heart Rate Variability, Exercise
Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance
Heart rate variability (HRV) is a measure of the variation in time between each heartbeat. It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness…
- Trial name
- NCT06425939
- Testing
- Force plate assessment, Whoop wrist band
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Heart Rate Monitoring, Vagal Bradycardia
Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy
This prospective observational cohort study will assess whether perioperative short-term heart rate variability (HRV) indices and early inflammatory cytokine levels are associated with respiratory and cardiac adverse events in…
- Conditions
- Heart Rate Monitoring, Vagal Bradycardia, Adenotonsillar Hypertrophy, Tonsillitis; Hypertrophic
- Trial name
- NCT07719439
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Duzce University
Suppurative Otitis Media
The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis
ear swabs will be collected from 120 patients with established CSOM at the ear-nose-throat (ENT) outpatient clinic at the Ziv medical center, and 120 swabs will be taken from children with Otitis Media with Effusion (OME)…
- Trial name
- NCT03456739
- Volunteers
- 240 people
- Sponsor
- Ziv Hospital
Healthy
Genetic Response to Warfarin in Healthy Subjects
The purpose of this study is to determine the importance of genetic differences on individuals' response to warfarin in a group of healthy subjects.
- Trial name
- NCT01520402
- Testing
- Warfarin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
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