Clinical trials: Variability
Blood Glucose Variability, Cardiac Surgical Procedures
Glycemic Variability and Autonomic Nervous System in Cardiac Surgery Patients
On-pump coronary artery bypass graft (CABG) and valve replacement surgeries are high-risk procedures. Among the risk factors for postoperative complications, perioperative hyperglycemia and blood glucose variability have been…
- Conditions
- Blood Glucose Variability, Cardiac Surgical Procedures, Autonomic Nervous System
- Trial name
- CAESAR (NCT05454735)
- Testing
- coronary artery bypass surgery, aortic valve replacement surgery
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Thermogenesis by Different-dosage Mustard Flour Footbaths
Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers
A study to explore whether different dosages of mustard flour in footbaths cause different effects on warmth development as well as on general well-being and the autonomic nervous system.
- Trial name
- NCT04321720
- Testing
- 3-g mustard footbath, 6-g mustard footbath, 12-g mustard footbath
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Coronary Heart Disease (CHD), Anxiety Disorders
Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety
The goal of this clinical trial is to test whether real-time fNIRS-BCI neurofeedback targeting the right dorsolateral prefrontal cortex (right DLPFC), using active volitional control during a slow-wave auditory acoustic paradigm…
- Trial name
- HEART-SET-1 (NCT07238920)
- Testing
- Real-time fNIRS-ECG neurofeedback
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shenyang Medical College
Allergy, Hypersensitivity, Immediate
Head-to-Head Comparison Study Between Different FDA Registered Allergy Skin Test Applicators
This clinical study, titled "Head-to-Head Comparison Study between Different FDA Registered Allergy Skin Test Applicators," aims to compare the reliability and clinical performance of three skin prick test (SPT) devices…
- Conditions
- Allergy, Hypersensitivity, Immediate, Ig-E Mediated Food
- Trial name
- NCT07400718
- Testing
- AllerTest-10 Multi-Head Skin Test Device, Skintestor OMNI Multi-Head Skin Test Device, Multi-Test II Multi-Head Skin Test Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- QHSLab, Inc.
Stress, Psychological, Physiological
Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
The purpose of this study is to determine whether inversions (specific yoga postures in which the heart is higher than the head) and other dynamic and static yoga postures affect heart rate variability, oxygen uptake, blood…
- Trial name
- NCT01305096
- Testing
- Yoga intervention
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pain, Postoperative
Heart Rate Variability and Postoperative Pain
Postoperative pain stimulates the autonomic nervous system, induces the production of pro-inflammatory substances, reduces patient mobility and impairs vital functions.
- Trial name
- ECG-Spectral (NCT00438035)
- Testing
- ECG spectral
- Where
- France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Bordeaux
Obesity, Healthy Volunteer
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
Background: Researchers use mixed meal tolerance tests (MMTTs) to look at how people s bodies respond to eating a meal. However, researchers do not agree on how to decide the number of calories to give in each meal.
- Trial name
- NCT06223555
- Testing
- Fixed Mixed Meal Test, Adjusted Mixed Meal Test
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Multiple Sclerosis
Effect of Acupuncture on Heart Rate Variability in Multiple Sclerosis
The Objective of this study is to evaluate the heart rate variability in individuals with multiple sclerosis during the applicability of Acupuncture, to analyze the behavior of the autonomic nervous system before, during, and…
- Trial name
- NCT05523466
- Testing
- Acupuncture Active
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Heart Rate Variability
Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness
The purpose of this randomized controlled trial was to compare the effectiveness of an HRV-BF intervention versus a health promotion active control intervention focused on improving mental health symptoms among people…
- Trial name
- HRV-BF (NCT05897580)
- Testing
- Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Virtual Reality
This study aims to examine whether listening to natural sounds in a noisy virtual reality environment compared to no natural sounds influences physiological markers.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- VEARS (NCT05679869)
- Testing
- Masking Sound, No masking sound
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Perfusion
The Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index
This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be randomly divided into three groups.
- Trial name
- NCT03048162
- Testing
- sodium chloride, Hydroxyethylstarch, Ringer-Lactate Infusion Solution Bag
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Old Age; Atrophy, Aging
High-Speed Resistance Training Program in Independent Older Adults
The aims of the present investigation are: a) to determine the effects of a 16-weeks high-speed resistance training program on health parameters in independent older adults; and b) to verify the durability of the effects after 6…
- Trial name
- NCT05586087
- Testing
- Experimental group
- Where
- Portugal
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Évora
Burnout, Professional, Stress, Psychological
Foundational Programs to Combat Clinician Stress
This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital…
- Conditions
- Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being
- Trial name
- FACCTS (NCT07220421)
- Testing
- Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
- Where
- 6 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Anxiety, Cognitive Deficit
Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits
This study investigates the potential of cranial electrotherapy stimulation to mitigate anxiety induced cognitive deficits
- Trial name
- NCT04961112
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Tufts University
Major Depressive Disorder
Intradermal Acupuncture as an Adjunct to SSRI Tapering in Major Depressive Disorder
This randomized controlled trial aims to evaluate the clinical efficacy of intradermal acupuncture as an adjunctive intervention to assist selective serotonin reuptake inhibitor (SSRI) dose reduction or discontinuation in adult…
- Trial name
- NCT07390981
- Testing
- Selective Serotonin Reuptake Inhibitors (SSRIs), Intradermal Acupuncture
- Volunteers
- 114 people
- Sponsor
- First People's Hospital of Hangzhou
Diabetes Mellitus, Type 2
The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy
The goal of this clinical trial is to learn if SGLT2 inhibitor Henggliflozin works to improve glucose variability in type 2 diabetes and if Henggliflozin can benefit immunosenescence.
- Trial name
- HOLIDYA (NCT06818851)
- Testing
- Henggliflozin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Overweight and Obesity
Diet-Induced Variability in Appetite (DIVA)
The aim of this study is to test the hypothesis that dietary weight loss (WL) through alternate day fasting (ADF) will enhance appetite control, health markers and wellbeing following WL compared to standard daily calorie…
- Trial name
- DIVA (NCT03447600)
- Testing
- Alternate Day Fasting, Continuous dietary restriction
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Diabetic Kidney Disease
Gut Microbiota and Serum Metabolites as Predictors of Glycemic Variability and Outcomes in Diabetic Kidney Disease
Diabetic kidney disease (DKD) is one of the main complications of diabetes and a leading cause of end-stage kidney disease. Blood glucose variability is closely associated with disease progression in individuals with DKD.
- Trial name
- NCT07352436
- Volunteers
- 270 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Coronary Artery Disease
Clopidogrel and Response Variability Investigation Study 2
To evaluate the role of the genetic variant 2C19*2 on the pharmacodynamic response as assessed by optical aggregometry and on the pharmacokinetic response as assessed by measuring active metabolites following an oral…
- Trial name
- CLOVIS2 (NCT00822666)
- Testing
- clopidogrel
- Where
- France
- Volunteers
- 109 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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