Clinical trials: Variability
Hypotension,Controlled
Correlation Analysis of the Effects of Management Pressure Goals and Control Volume Goals in Patients in Spinal Surgery
The investigators study 160 patients undergoing spinal surgery.Participants will be randomly divided into study group and control group.The study group will receive controlled hypotension by nitroglycerin and be divided into 3…
- Trial name
- NCT03917004
- Testing
- Nitroglycerin
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liang Bing
Cardiometabolic Risk Factors
Physical Exercise on Physiological Adaptation Capacity and Chronic Pain in Individuals With Cardiovascular Risk
This research focuses on studying the effects of a 12-week exercise program on the health of individuals at risk of heart disease.
- Trial name
- NCT06201273
- Testing
- High-Intensity Interval Training, Resistance Training
- Where
- Chile
- Volunteers
- 192 people
- Sponsor
- Universidad San Sebastián
Kidney Disease
Interdialytic Kt/V Variability Measurement With Adimea (IVP STUDY)
Session-to-session variations in delivered Kt/V that may cause failure to achieve the prescribed dialysis dose may be significant in regular clinical practice.
- Trial name
- IVP (NCT01947829)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- B.Braun Avitum AG
Autonomic Nervous System Activity, Cardiovascular
Investigation of Autonomic Stress Response Patterns in College Students With Varying Physical Activity Levels
This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes).
- Conditions
- Autonomic Nervous System Activity, Cardiovascular, Physical Activity Level
- Trial name
- ANS Stress/PA (NCT07360821)
- Testing
- Cardiopulmonary Exercise Testing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Stress
Stress, EEG, ECG, and Chiropractic
The Life University Center for Chiropractic Research is conducting a study to better understand the relationship between subjective stress measures and brain patterns during resting state and an auditory oddball task.
- Trial name
- BLI (NCT05245409)
- Testing
- Chiropractic adjustment using an activator
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7)
NOTE: This is the sixth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919163
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Chronic Low-back Pain
Myofascial Trigger Point Release and Paced Breathing Training for Chronic Low Back Pain
A study to explore whether two different treatment approaches, myofascial trigger point release and core stabilization exercises, both with and without additional paced breathing training, can help patients with chronic low back…
- Trial name
- NCT04107597
- Testing
- Core stabilization exercises, Core stabilization exercises and paced breathing training, Myofascial trigger point release
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Healthy, Nutrition
Glycaemic Responses to a Food Intake Sequence Intervention in Free-living Elite Female Athletes
The goal of this clinical trial is to investigate the impact of a food intake sequence intervention under free-living conditions on glycaemic responses in elite female athletes.
- Conditions
- Healthy, Nutrition, Glycemic Variability, Dietary Intervention
- Trial name
- NCT07247513
- Testing
- Carbohydrate-last meal pattern, Carbohydrate-first meal pattern
- Where
- Portugal
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Behçet's Syndrome (BS)
Prospective Multiethnic Validation of the Behçet's Syndrome Overall Damage Index (BODI)
PROBE is an observational multicenter cohort study, consisting of a cross-sectional and a 5-years prospective phase, designed to target the major study objectives, such as testing the comprehensiveness of the Behçet's syndrome…
- Trial name
- PROBE (NCT07073261)
- Where
- Italy
- Volunteers
- 970 people
- Sponsor
- University of Cagliari
Glucocorticoids Toxicity, Glucose Intolerance
Pharmacogenomics of the Variability in the In Vivo Response to Glucocorticoids
This study evaluates the effect of acute administration of oral prednisone in white blood cells counts and glucose tolerance and the relationship of these measures with changes in gene expression in healthy volunteers.
- Trial name
- NCT03023891
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Heart Rate Variability, Psychological Resilience
Mindfulness-Based Self-Compassion and Vagal Nerve Stimulation on Heart Rate Variability, Psychological Resilience, and Sleep Quality
This study was conducted to determine the effects of a mindfulness-based self-compassion intervention and vagal nerve stimulation on heart rate variability, psychological resilience, and sleep quality in earthquake victims.
- Conditions
- Heart Rate Variability, Psychological Resilience, Sleep Quality
- Trial name
- NCT06501027
- Testing
- Mindfulness Based Self Compassion
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- İstanbul Yeni Yüzyıl Üniversitesi
Circulatory Failure
NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy
1 in 1000 babies are born suffering from a lack of oxygen. This is known as hypoxic ischemic encephalopathy (HIE). Infants with this condition can suffer multiple organ problems.
- Trial name
- NCT02051894
- Testing
- Dobutamine
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Anesthesia, Local, Surgery
Effect of Virtual Reality (VR) Therapy on Patients Undergoing Hand Surgery Under Ultrasound-guided Regional Anesthesia
By means of an investigator-initiated, monocentric, single-blinded, prospective, randomized controlled superiority trial, the effect of virtual reality (VR) therapy on patients undergoing ambulatory hand surgery under…
- Conditions
- Anesthesia, Local, Surgery, Hand Injuries
- Trial name
- NCT05183412
- Testing
- The Sedakit Oncomfort VR glasses (30-minutes Aqua program), Ultrasound-guided regional nerve block and hand surgery without VR glasses, Ultrasound-guided regional nerve block and hand surgery with VR glasses
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Jessa Hospital
Acute Myocardial Infarction
Daily Variability of Platelet Aggregation in Patients With Myocardial Infarction Treated With Prasugrel and Ticagrelor
The aim of this study is to compare circadian variability of antiplatelet effect of prasugrel and ticagrelor maintenance doses during the initial days after acute myocardial infarction.
- Trial name
- DRAGON (NCT03454841)
- Testing
- Prasugrel, Ticagrelor
- Where
- 2 sites in Poland
- Volunteers
- 73 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Depression, Burnout
Heart Rate Variability, Physical Activity and Exhaustion in the Inpatient Treatment of Stress-Related Disorders
The goal of this observational study is to learn about heart rate variability and physical activity in inpatients with stress-related disorder.
- Conditions
- Depression, Burnout, Stress Related Disorder
- Trial name
- HARMODI (NCT05874856)
- Testing
- Heart rate variability, blood pressure and pulse wave velocity, Assessment of cognitive function, balance, strength and cardiorespiratory fitness, Monitoring of physical activity and sleep
- Where
- Switzerland
- Volunteers
- 153 people
- Sponsor
- Arno Schmidt-Trucksäss
Genotype, Pain
Genetics and Pain Severity in Sickle Cell Disease
Background: Pain is the most common symptom of sickle cell disease. Episodes of severe sickle cell pain are known as "crises." High rates of pain crises are associated with a higher risk of early death.
- Conditions
- Genotype, Pain, Genetic Variation, Quantitative Sensory Testing (QST)
- Trial name
- NCT01441141
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 2 Diabetes
Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects
Type 2 diabetes (T2D) could modulate CYP450 activities involved in drug-metabolism and cardiovascular homeostasis. We propose to carry out, for the first time, a comprehensive characterization of the effects of T2D on the…
- Trial name
- NCT02291666
- Testing
- CRCHUM-MT cocktail
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Obesity
Blood Glucose Variability in Obese Youth Participating in a Lifestyle Modification Program
The purpose of this study is to measure blood glucose variation in youth prior to and after participation in a healthy lifestyle intervention program.
- Trial name
- NCT02296034
- Sponsor
- Yale University
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Healthy Subjects
Variability of Impedance Pneumography Tidal Breathing Flow-volume Curves During Sleep in Healthy Children
This is an observational study for the assessment of normal overnight variation in small healthy children using the Ventica Lung Function Testing System.
- Trial name
- NCT03551236
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Revenio Research
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