Clinical trials: Variability
Obstructive Sleep Apnea
Vitamin D Levels and Heart Rate Variability on Endothelial Function Via RAAS Augmentation in OSA
The role of obstructive sleep apnea (OSA) in contributing to hyperaldosteronism, which can lead to increased morbidity and mortality, is less well-established.
- Trial name
- RAAS_OSA (NCT05232201)
- Where
- Malaysia
- Volunteers
- 150 people
- Sponsor
- University Malaysia Sarawak
Exercise, Cardiorespiratory Fitness
Addressing Individual Variability in Response to Exercise
In this proposal, the investigators challenge the assumption that following the physical activity guidelines implies benefit for ALL adults, and that if benefit is not achieved in response to first line therapy, it will be by…
- Trial name
- NCT04304092
- Testing
- Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr. Robert Ross
Autonomic Nervous System Imbalance, Blood Pressure
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
- Conditions
- Autonomic Nervous System Imbalance, Blood Pressure, Inflammation, Vasoconstriction
- Trial name
- NCT02238028
- Testing
- Wear respirator
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fudan University
Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control.
Effects of Inspiratory Muscle Training on Cardiovascular Function in Hypertension.
The purpose of this study is to determine inspiratory muscle training effects on blood pressure, functional capacity and quality of life in hypertensive patients.
- Conditions
- Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control., Improvement of Functional Capacity., Improvement of Quality of Life.
- Trial name
- TREMVEN (NCT01250444)
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Neoplasms
Interindividual Genetic Variability as a Determinant of Chemotherapy Toxicity and Response in Pediatric Bone Marrow Transplantation Patients
The purpose of this study is to develop tests that will allow us to determine who will react differently to the drugs used to treat cancer.
- Trial name
- NCT00578630
- Testing
- buccal swabs and obtaining peripheral blood
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy Volunteers
The Effects of Sex, Body Mass Index, Day-to-Day Subject Variability for the ProLung Test and Variability of a Single Device When Volume-Averaged Thoracic Bioconductance is Measured With the ProLung Test
Assess the repeatability of the ProLung Test
- Trial name
- NCT03993028
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fresh Medical Laboratories
Healthy
Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults
Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability.
- Trial name
- NCT05931237
- Testing
- Cranberry extract capsules
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Laval University
Sleep, Heart Rate
A Digital Mindfulness Intervention to Improve Sleep Efficiency and Heart Rate Variability in Healthy Adults
This study tested whether a 10-day smartphone app-based mindfulness program can improve sleep and reduce physiological stress in healthy adults.
- Trial name
- NCT07469644
- Testing
- App-based mindfulness program (Headspace via Ōura app)
- Where
- Denmark
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Pulmonary Disease, Chronic Obstructive
Summer-Winter Variability in the Level of Physical Activity in Daily Life in Brazilian and Belgian Patients With COPD
Up to this moment, the majority of studies assessing the level of physical activity in daily life in patients with COPD are limited to a cross-sectional design, which does not take into account natural variation of physical…
- Trial name
- NCT01779960
- Testing
- Londrina, Leuven
- Where
- 2 sites in Belgium, Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Estadual de Londrina
Myasthenia Gravis
The Effectiveness of Bu Zhong Yi Qi Tang in Patients with Myasthenia Gravis
Research Background: According to the Myasthenia Gravis Foundation of America (MGFA, 2015), the estimated prevalence of myasthenia gravis is 14-20 per 100,000 people, with a higher prevalence in young female individuals compared…
- Trial name
- NCT06881173
- Testing
- Bu Zhong Yi Qi Tang
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Cheng, yu-ting
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lung Function, Heart Rate Variability
Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers
Introduction: Non-mechanized sugar cane harvesting preceded by burning, an important and prevalent professional activity of agribusiness segment of the Brazilian economy, exposes workers and people of neighboring towns to high…
- Conditions
- Lung Function, Heart Rate Variability, Oxidative Stress, Systemic Inflammatory Response
- Trial name
- NCT01371188
- Where
- Brazil
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Obesity, Type D Personality
The Stress-release Effects of Exercise in Obese Are Determined by DS14 Score and T-cell Activation Status
The purpose of the study was to analyze negative affectivity (NA) and social inhibition (SI) inquired by DS14 score in type D personality (distressed personality) to the relation of autonomic regulation of heart function (HRV)…
- Conditions
- Obesity, Type D Personality, Coronary Heart Disease
- Trial name
- NCT02493413
- Volunteers
- 30 people
- Sponsor
- Institute for Preventive Medicine, Trzaska
Diabetes Mellitus, Type 2
Toujeo Versus NPH Self-titration Study
This is a 24 week, multicentre, prospective, randomized, controlled, parallel-designed (1:1) pilot study.The study will compare glycemic variability in patients treated with insulin glargine U300/ml insulin versus conventional…
- Trial name
- NCT03389490
- Testing
- Insulin Glargine 300 UNT/ML, Neutral protamine hagedorn insulin
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Elaine Chow
Bipolar Disorder
Dietary Intervention for Bipolar Disorder
Bipolar disorder (BD) is a chronic, often disabling illness, and many individuals remain symptomatic despite pharmacotherapy. Significant mood variability often persists throughout the lifespan and predicts relapse, leading to…
- Trial name
- NCT02272010
- Testing
- Experimental Diet, Comparator Diet
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Milton S. Hershey Medical Center
Autonomic Nervous System, Nerve Block
Heart Rate Variability and Electroencephalography Analysis in Laparoscopic Surgery With or Without Transversus Abdominis Plane Block
Heart rate variability(HRV) and electroencephalography(EEG) has been used widely in anesthetic practice nowadays. One of the most dominant applications is the nociception-analgesia balance.
- Conditions
- Autonomic Nervous System, Nerve Block, Laparoscopy, Anesthesia and Analgesia
- Trial name
- NCT04539080
- Testing
- transversus abdominis plane block
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Chronic Migraine, Headache
Effect of Auricular Vagus Nerve Stimulation in Women With Migraine Disease
The aim of the study was to investigate the effectiveness of non-invasive auricular vagus nerve stimulation on pain and pulse variability in women aged 18-55 years with migraine.
- Trial name
- NCT05748535
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bahçeşehir University
Healty Volunteers
Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity
This study will examine the immediate (acute) effects of a single myofascial release technique applied to the thoracolumbar fascia on brain activity in healthy young adults aged 18-25.
- Trial name
- MFR-EEG (NCT07728617)
- Testing
- Thoracolumbar Fascia Myofascial Release (Pilat MIF Crossed-Hands Technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hitit University
Parkinson Disease, Gait, Unsteady
Effect of Haptic Cueing on Long-Range Autocorrelations in Parkinson's Disease Gait Variability
Parkinson's Disease (PD) patients suffer from gait impairments responsible for falls and bad quality of life: reduced speed and stride length, randomness in the temporal organization of stride duration variability (reduced…
- Trial name
- NCT05790759
- Testing
- No cueing versus Haptic cueing versus Auditory cueing during parkinson's disease gait
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Depression Symptoms, Chronic Pain
Effect of Auricular Press Needle on Improvement of Patient Health Questionnaire-9 (PHQ-9) and Heart Rate Variability (HRV) Patient With Depression Symptoms in Chronic Pain
Depression is characterized by behavioral, cognitive and emotional changes. Depression can have a negative impact on decreasing quality of life because in many cases it occurs long-term.
- Trial name
- NCT06401070
- Testing
- Plesterin, Press needle acupuncture
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
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