Clinical trials: Variability
Myotonic Dystrophy Type 1
Multicenter Observational Study of Myotonic Dystrophy Type 1
The purpose of the study is to determine the best ways to assess how people are affected by myotonic dystrophy type 1 (DM1). The study will assess walking speed, muscle strength, muscle size, myotonia, heart rhythm, mental…
- Trial name
- MOS-DM1/POP (NCT02308657)
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Posttraumatic Stress Disorder (PTSD), Depression - Major Depressive Disorder
To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder
This study aims to investigate the immediate neurophysiological and autonomic effects of two noninvasive brain stimulation protocols-prolonged intermittent theta-burst stimulation (prolonged iTBS) and high-frequency repetitive…
- Trial name
- NCT07327385
- Testing
- Prolonged Intermittent Theta-Burst Stimulation (prolonged iTBS), High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.
Ischemic Heart Disease
HeartTrends Heart Rate Variability (HRV) Algorithm for the Diagnosis of Myocardial Ischemia
The investigators intend to prospectively enroll consecutive patients, without known ischemic heart disease, referred by their physician for routine exercise MPI at a tertiary care center.
- Trial name
- NCT01657006
- Where
- Israel
- Volunteers
- 450 people
- Sponsor
- Sheba Medical Center
Heart Rate Variability
Short- and Long-term HRV Measurements After Osteopathic Myofascial Thoracic Manipulations
The adaptation of the heart to react to any stimulus is called heart rate variability (HRV). Moreover, HRV is now used as a health index.
- Trial name
- NCT04234958
- Testing
- Osteopathic manipulative treatment
- Where
- Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Inherited Retinal Dystrophy, Retinitis Pigmentosa
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models
Inherited retinal dystrophies (IRDs), a large group of heterogeneous and rare disorders, may result in irreversible bilateral visual loss and blindness.
- Conditions
- Inherited Retinal Dystrophy, Retinitis Pigmentosa, Macular Dystrophy
- Trial name
- NCT05793515
- Testing
- whole genome sequencing
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Superiore di Sanità
Hypertension
Cardiovascular Autonomic Control Evaluation Through Cardiac Frequency Variability in Hypertensive Patients
Analyzing cardiovascular evaluation measures in the multidisciplinary and in the conventional treatment of hypertensive patients will provide better parameters for comparing the two approaches.
- Trial name
- NCT02211248
- Testing
- Multidisciplinary assistance, Conventional treatment and follow up
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Developmental Disability, Chronic Disease
QoL and Stress in Parents of Children With Developmental Disabilities and Chronic Disease
The aim of this cross-sectional study is to investigate the level of stress and quality of life in parents of children with developmental disabilities (Down syndrome, autism spectrum disorder, pervasive developmental disorder…
- Conditions
- Developmental Disability, Chronic Disease, Down Syndrome, Autism Spectrum Disorder
- Trial name
- NCT03602378
- Testing
- salivary cortisol, Holter Medilog AR12 Plus, Polar V800
- Where
- 2 sites in Croatia
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Spinal Induced Hypotension
PVI for Prediction of Spinal Induced Hypotension
The hypothesis is that plethysmography variability index can predict the occurrence of hypotension after spinal anesthesia for cesarean delivery
- Trial name
- NCT01967914
- Testing
- PVI
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Tai Chi Practitioner, Qigong Practitioner
The Relationship Between Cranial Near-InfraRed Oxygenation(NIRO) and Heart Rate Variability During Mental Exercise
The objective of this study is to investigate the effect of Tai Chi and Qigong practice on cranial oxyhaemoglobin level, blood pressures and autonomic nervous system responses.
- Trial name
- NCT01088113
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depression
Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)
This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded…
- Trial name
- NCT06455527
- Testing
- Active Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Arterial Stiffness, Endothelial Function
Focus On Stiffness Reduction, Endothelial Function and Autonomic Nervous System
Myocardial infarction is related with endothelial function, arterial stiffness and autonomic nervous system dysfunction, but also with arterial hypertension.
- Conditions
- Arterial Stiffness, Endothelial Function, Autonomic Nervous System, Acute Coronary Syndrome
- Trial name
- FOREVER (NCT02195388)
- Testing
- comprehensive cardiac rehabilitation
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Lodz
Critically Ill
Cardioventilatory Coupling in Critically Ill Patients
This study measures the cardioventilatory coupling in critically ill patients during mechanical ventilation in controlled mode (pressure controlled) and in patient-driven mode (pressure support and neurally adjusted ventilatory…
- Trial name
- NCT02286869
- Testing
- Three different mechanical ventilation modes
- Where
- 2 sites in Italy
- Volunteers
- 22 people
- Sponsor
- ASST Fatebenefratelli Sacco
Pulmonary Hypertension, Arrhythmias, Cardiac
Arrhythmias in Pulmonary Hypertension Assessed by Continuous Long-term Cardiac Monitoring
Arrhythmias are considered a prominent phenomenon in pulmonary hypertension (PH) as the disease progresses. According primarily to retrospective studies with up to 24 hours of monitoring, supraventricular tachycardias (SVT) can…
- Conditions
- Pulmonary Hypertension, Arrhythmias, Cardiac, Heart Rate Variability, Risk Assessment
- Trial name
- ASPIRE (NCT04554160)
- Testing
- Loop recorder implantation, A smartwatch
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Burnout, Burnout Syndrome
Continuous Heart Rate Variability Monitoring in Doctors; Understanding Patterns of Stress and Recovery and Their Relationship With Self-reported Resilience, Burnout and Wellbeing.
Burnout is an increasing concern in the medical professions. This study aims to utilise established, validated self-report measures combined with continuous heart rate variability measurements to better understand the stress and…
- Conditions
- Burnout, Burnout Syndrome, Occupational Stress, Stress
- Trial name
- HEART-ED (NCT06721312)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Benign Paroxysmal Positional Vertigo, Vertigo
The Cardiac Autonomic Control System Response to Vestibular Stimulation in Subjects With and Without BPPV
The vestibular system in the inner year is an important system in the body which is responsible for balance. In addition, there is evidence that the vestibular system plays a role in maintaining blood pressure while changing body…
- Conditions
- Benign Paroxysmal Positional Vertigo, Vertigo, Autonomic Nervous System
- Trial name
- NCT03867019
- Testing
- Heart rate variability parameters monitoring
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Paroxysmal Atrial Fibrillation
Effects of Mediyoga in Patients With Paroxysmal Atrial Fibrillation
The purpose of this study is to determinate if mediyoga has effects in quality of life, heart rate variability, blood pressure , heart rate in patients with paroxysmal atrial fibrillation (PAF).
- Trial name
- NCT01789372
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Danderyd Hospital
Chronic Kidney Disease
Heart Rate Variability & Fatty Acid Status: Haemodialysis Patients
Studies suggest that dietary omega-3 fatty acids influence the extent to which the time interval between each heart beat varies (heart rate variability; HRV).
- Trial name
- NCT02014792
- Where
- 3 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- King's College London
Stroke
Which Parameters of Short-term Blood Pressure Variability Best Predict Early Outcomes in Acute Ischemic Stroke
Previous studies on the association between blood pressure variation (BPV) in acute ischemic stroke and functional outcomes yield conflicting result.
- Trial name
- BPV (NCT02675972)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Dongguan People's Hospital
Intraocular Pressure
Intra-observer and Inter-observer Variability With Dynamic Contour Tonometry.
The aim of the protocol is to document intra-observer and inter-observer variability with dynamic contour tonometry, and will also test the theory that pulse amplitude, as measured by dynamic contour tonometry, is correlated with…
- Trial name
- NCT00818233
- Testing
- Dynamic contour tonometry
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
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