Clinical trials: Variability
COPD, Congestive Heart Failure
Use of Non Invasive Hemodynamic Cardiovascular Monitoring to Evaluate Emergency Department Patients
This study is an observational prospective pilot trial that utilizes finger cuff non invasive hemodynamic monitoring (NexfinHD Monitor) to assess 4 different groups (CHF/COPD, Trauma, Sepsis, Stroke) of patients on arrival to the…
- Conditions
- COPD, Congestive Heart Failure, Trauma, Sepsis
- Trial name
- NCT00851214
- Testing
- NexfinHD Monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Chronic Low Back Pain (CLBP), Chronic Neck Pain
Comparative Analysis of Heart Rate Variability in Patients with Cervical Pain, Lumbar Pain, and Healthy Controls
This is a cross-sectional study designed to evaluate potential differences in heart rate variability (HRV) indices based on the affected body region (cervical vs lumbar) in individuals with chronic pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Neck Pain, Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06890793
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Sleep Problems, Depressive Disorder and Anxiety Disorders
The Impact of Melatonin Lotion on Sleep and Mental Health
The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health.
- Trial name
- NCT06768749
- Testing
- Melatonin lotion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Redlands
Asthma, Obesity
Study of the Physiology of the Asthma of the Obese Subjects. Breathing Obesity Asthma Study (BOA)
Asthma is more frequent in obese women, but the mechanisms underlying the causes of this increased frequency are unknown and are different from usual asthma pathophysiology (associated with allergy).
- Trial name
- BOA (NCT00577733)
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder
Recording Heart Rate Variability During Eye Movement Desensitisation Reprocessing With or Without Eye Movement
The purpose of the study is to gain greater insight into Eye Movement Desensitisation Reprocessing (EMDR). EMDR is an NHS recommended treatment, which can significantly reduce trauma symptoms.
- Trial name
- EMDR;PTSD (NCT02565563)
- Testing
- Eye Movement Desensitisation Reprocessing, HeartMath measuring Heart Rate Variability (HRV)
- Sponsor
- University of Edinburgh
Haemophilia
Inter Individual Variability in Initiation Pathway Activation and Regulation and Phenotypic Heterogeneity in Patients With Haemophilia A and B
Severe haemophilia A and B (SHA, SHB) are X - linked inherited bleeding disorders, characterised by factor VIII and IX levels of <1 IU/dL respectively.
- Trial name
- InPath (NCT03287999)
- Testing
- Thrombophilia screen, Initiation pathway analysis
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Athletic Performance, Recovery
UCLA Magnesium Formulation Athlete Study
This randomized, double-blind, placebo-controlled trial will compare magnesium glycinate, magnesium L-threonate, and placebo in UCLA varsity athletes.
- Conditions
- Athletic Performance, Recovery, Sleep
- Trial name
- Mg-Form (NCT07640685)
- Testing
- Magnesium glycinate, Magnesium L-threonate
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Overweight and/or Obesity
Body-Based and Mind-Based Regulation in Overweight and Obese Women
This study will compare two regulation-based approaches in women with overweight or obesity. The first approach is a body-based regulation program including breathing awareness, body-awareness-based yoga practices, non-invasive…
- Trial name
- NCT07738263
- Testing
- Body-Based Regulation Program, Mind-Based Regulation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Blood Pressure, Blood Pressure Variability
This Study Aims to Assess the Performances of Optical Blood Pressure Monitoring Device, tBPC Product With Reference to ISO 81060-3:2022
In this study, according to the latest released ISO 81060-3:2022 standard requirements, non-invasive blood pressure measurement by cuff at the start and the end time points will be used as oCareTM BP100 start-to-end blood…
- Trial name
- NCT06815614
- Testing
- A Photoplethysmography-Based Continuous Automated Non-Invasive Sphygmomanometer
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taiwan Biophotonic Corporation
PTSD
ACT With Feedback for Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to explore the efficacy of Attention Control Training with the inclusion of feedback for Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT05242263
- Testing
- Attention Control Training (ACT) with ABV feedback
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Diabetic Pediatric Patients With Type 1 Diabetes
Effect of an Educational Mobile Game on HbA1c and Glycemic Variability in Children With Type 1 Diabetes: A Randomized Controlled Trial
This is a prospective randomized parallel two group pharmacist-led interventional study. The study will involve introduction of the mobile game to pediatric diabetic patients to improve their blood glucose level.
- Trial name
- NCT05697484
- Testing
- educational game
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Physical Inactivity, Overweight
Individual Variability in Energy Compensation After a 12-Week Supervised Exercise Intervention
This prospective, single-arm interventional study will investigate why adults receiving the same prescribed dose and relative intensity of exercise show divergent changes in energy balance, body weight, and body composition.
- Conditions
- Physical Inactivity, Overweight, Obesity
- Trial name
- NCT07893249
- Testing
- Supervised Aerobic Exercise Programme
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Type 2 Diabetes
Exercise as a Tool for Studying the Mechanisms and Applicability of Glycemic Variability
The aim this study is characterize glycemic variability using linear and nonlinear mathematical tools, under basal conditions and in response to specific protocols acute exercise that evoke oxidative stress and inflammation in…
- Trial name
- ETSMAGV (NCT02262208)
- Testing
- Aerobic Exercises, Eccentric Exercise, Continuous glucose monitoring system (Guardian, Medtronic, Northridge, USA)
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stress
The Effect of Massage Therapy to Control Night Shift Related Stress
Background: The sympathetic and parasympathetic branches (SNS and PNS) of the autonomic nervous system (ANS), keep our body in a state of balance, which can be disturbed in situations of uncontrolled stress.
- Trial name
- NCT02247089
- Testing
- Massage Therapy, Journal reading (No massage therapy)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prostate Cancer
Inter-observer Variability in the Segmentation of Prostate Tumour Lesions Using Multiparametric MRI (VARIOP)
Following the major technological and scientific advances in external radiotherapy in recent decades, thanks to the use of three-dimensional conformal techniques combined with intensity modulation, image-guided radiotherapy has…
- Trial name
- VARIOP (NCT05996289)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability
Predicting Postoperative Delirium With Heart Rate Variability Obtained by Analgesia Nociception Index
The aim of this pilot study is to establish a correlation between perioperative heart rate variability (HRV) as an expression of the shift in the balance of the autonomic nervous system and the occurrence of postoperative…
- Conditions
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability, Biomarkers
- Trial name
- DANI (NCT06709482)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Urinary Bladder, Overactive
The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial
The optimal medication for women with nocturia remains uncertain. This clinical trial aimed to determine the most effective medication for women with overactive bladder and nocturia.
- Trial name
- NCT07114640
- Testing
- Mirabegron 25mg, Solifenacin 5 mg, Tolterodine 4 mg
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Far Eastern Memorial Hospital
Depressive Disorder, Major, Depression, Bipolar
The Effects of tDCS on Depressive Symptoms,Neurocognitive Function and HRV in Unipolar Depression and Bipolar Depression
The study aimed to investigate whether transcranial direct current stimulation could improve depressive symptoms, neurocognitive function and modulate heart rate variability in unipolar and bipolar depression.
- Conditions
- Depressive Disorder, Major, Depression, Bipolar, Electricity; Effects
- Trial name
- NCT03287037
- Testing
- tDCS over DLPFC
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Type 2 Diabetes
MAGE of Anagliptin Compared With Sitagliptin With Type 2 Diabetes Mellitus
An exploratory study to evaluate the Effect of Improving Glycemic Variability of Anagliptin Compared with Sitagliptin in Patients with Type 2 Diabetes Mellitus
- Trial name
- ACACIA (NCT04810507)
- Testing
- Anagliptin BID Treatment
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- JW Pharmaceutical
Brain Concussion, Mild Traumatic Brain Injury
A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms
Mild traumatic brain injury (mTBI), also known as concussion, is of great concern in the youth population, with incidences of injury steadily increasing within the past few years.
- Trial name
- NCT03217695
- Testing
- Mindfulness-based Yoga Arm
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
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