Clinical trials: Varicella Zoster Virus Infection
Varicella Zoster Virus Infection, Herpes Simplex Virus Infection
Bioequivalence Study in Healthy Volunteers of a New Paediatric Formulation of Valacyclovir
A new paediatric formulation (oral liquid) has been developed for flexible and accurate dosing of valacyclovir in children. To establish the bioavailability of this new formulation, healthy volunteers will be exposed to the new…
- Trial name
- VALID-I (NCT01689285)
- Testing
- valacyclovir tablet, valacyclovir oral solution
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Herpes Zoster, Herpes Zoster Vaccine
Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell) in Healthy Chinese Population Aged 40 Years and Older
The objective of this study was to evaluate the safety, immunogenicity and immune persistence of recombinant herpes zoster vaccine (CHO cells) with different adjuvant doses in healthy people aged 40 years and older.
- Trial name
- NCT06851832
- Testing
- Recombinant zoster vaccine(CHO cell)(low adjuvant), Recombinant Zoster Vaccine (CHO cell), Zoster Vaccine, Live
- Where
- China
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Herpes Zoster
Safety and Immunogenicity Study of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A When Administered Subcutaneously Intramuscularly in Adults Aged ≥50 Years
The purpose of this study is to assess the immunogenicity, safety, and reactogenicity of GSK Biologicals' Herpes Zoster (HZ) vaccine (GSK 1437173A) when administered subcutaneously (SC) as compared to intramuscularly (IM) to…
- Trial name
- NCT01777321
- Testing
- Herpes zoster vaccine GSK1437173A
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Kidney Transplant; Complications, Varicella Zoster Virus Infection
Herpes Virus Infections in Kidney Transplant Patients
Kidney transplant recipients are at increased risk of infections, including Varicella-zoster virus (VZV) infections. Vaccination against VZV is routinely offered to all kidney transplant recipients and candidates in Denmark.
- Conditions
- Kidney Transplant; Complications, Varicella Zoster Virus Infection, Vaccine-Preventable Diseases
- Trial name
- HINT (NCT05604911)
- Where
- 5 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- Susanne Dam Nielsen, MD, DMSc
Post Herpetic Neuralgia
A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN)
This study investigated the efficacy of the Lido-Patch (lidocaine 5% medicated plaster) in treatment of pain caused by PHN which is a neuropathic pain syndrome (nerve-related pain conditions) following an acute attack of herpes…
- Trial name
- NCT03745404
- Testing
- Lidocaine 5% medicated Plaster
- Volunteers
- 265 people
- Sponsor
- Grünenthal GmbH
Shingles, Vaccination Behavior
Nudging Patients to Increase Shingles Vaccination
The purpose of this study is to test whether messages encouraging patients to ask about a Shingrix vaccine at an upcoming appointment will increase Shingrix vaccination rates.
- Conditions
- Shingles, Vaccination Behavior, Behavior, Health
- Trial name
- NCT06238726
- Testing
- Reminder
- Where
- United States
- Volunteers
- 50,786 people
- Sponsor
- Geisinger Clinic
Herpes Zoster
Dose-finding Study of ASP2151 in Subjects With Herpes Zoster
To investigate the efficacy and safety of three different doses of ASP2151, as compared to valacyclovir hydrochloride in subjects with herpes zoster, and to determine the recommended clinical dose.
- Trial name
- NCT00487682
- Testing
- ASP2151, Valacyclovir hydrochloride
- Where
- 5 sites in Japan
- Volunteers
- 403 people
- Sponsor
- Astellas Pharma Inc
Measles, Mumps
A Study of An Approved Vaccine at Mumps Expiry Potency in Healthy Children 12 to 18 Months of Age (V205C-007)(COMPLETED)
The purpose of this study is to determine the mumps virus strength at the end of shelf-life (expiration date) of an approved vaccine.
- Conditions
- Measles, Mumps, Rubella, Varicella
- Trial name
- NCT00092391
- Testing
- Comparator: M-M-R(TM) II, measles, mumps, and rubella virus vaccine live, Comparator: VARIVAX(TM) Varicella Virus Vaccine Live (Oka-Merck)
- Volunteers
- 1,997 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Chickenpox, Rubella
MMR and Varicella Vaccine in Premature Infants
This research is designed to address the question, "Does the relative deficit in vaccine immunogenicity in extremely premature infants persist beyond the first 6 months of life?" We propose to measure the immunogenicity of…
- Conditions
- Chickenpox, Rubella, Rubeola, Mumps
- Trial name
- NCT00156559
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Systemic Lupus Erythematosus
Zostavax in Systemic Lupus Erythematosus
Individuals with systemic lupus erythematosus (SLE, lupus) appear to be at increased risk for the development of shingles, a painful reactivation of the varicella zoster virus that causes chicken pox.
- Trial name
- NCT01474720
- Testing
- Zostavax vaccine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation
Healthy, Healthy Adult
Seroprevalence and Vaccination Rate of Hepatitis B Virus and Varicella-zoster Virus Among Medical Students Under Immunizing Program
This study is a cross-sectional study. The study aims to determine the levels of immunity against hepatitis B virus and varicella-zoster virus in medical students.
- Trial name
- NCT06901362
- Where
- Thailand
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Neuralgia, Pain
Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia Pain
The purpose of this study is to gain initial information on the tolerability of high-dose capsaicin patches in patients with Painful Postherpetic Neuralgia.
- Conditions
- Neuralgia, Pain, Peripheral Nervous System Diseases, Herpes Zoster
- Trial name
- NCT00034710
- Testing
- Capsaicin Patch
- Where
- 8 sites in United States
- Volunteers
- 42 people
- Sponsor
- NeurogesX
Herpes Zoster
A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster
To evaluate the efficacy, optimal dose and efficacy trend of multiple subcutaneous injections of peginterferon α1b in patients with herpes zoster, and provide support for phase III clinical trials.
- Trial name
- NCT05492591
- Testing
- Peginterferon α1b, Peginterferon α1b with valacyclovir, Valacyclovir
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Institute Of Biological Products
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Herpes Zoster, Electroacupuncture
Electroacupuncture Regulation of Immune Cells in Herpes Zoster
Herpes Zoster (HZ), caused by the Varicella-Zoster Virus (VZV), is a common infection characterized by localized pain and blistering, with higher incidence in females.
- Conditions
- Herpes Zoster, Electroacupuncture, Immune
- Trial name
- NCT06643247
- Testing
- Drug, Electroacupuncture
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Postherpetic Neuralgia, Pain
Study of NGX-1998 for the Treatment of Postherpetic Neuralgia
The purpose of this study is to assess the efficacy, safety and tolerability of NGX-1998 applied for 5 minutes for the treatment of postherpetic neuralgia (PHN).
- Trial name
- NCT01228838
- Testing
- NGX-1998
- Where
- 35 sites in United States
- Volunteers
- 183 people
- Sponsor
- NeurogesX
Shingles, Herpes Zoster
Comparison of a Live Herpes Zoster Vaccine and a Recombinant Vaccine in 50-59 and 70-85 Year Olds
This study will compare the two vaccines that have been developed to prevent and/or lessen the effects of shingles. One vaccine is live (Zostavax, licensed by FDA) and the other, herpes zoster subunit (HZ/su), contains a piece of…
- Trial name
- NCT02114333
- Testing
- Zostavax, HZ/su vaccine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Organ Transplantation, Immunosuppression
The Safety of Oka Varicella in Children Prior to Solid Organ Transplantation
This study sought to determine the safety of the varicella vaccine pre- and post-transplantation when given to pediatric patients listed for solid organ transplantation.
- Trial name
- NCT00213304
- Testing
- varicella vaccine (VARIVAX)
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- The Hospital for Sick Children
Herpes Genitalis, Herpes Zoster
Study to Evaluate the Safety and Pharmacokinetics of Single Doses of ASP2151 in Healthy Male Subjects and the Effects of Food
The objective of this study is to evaluate the safety and tolerability of single rising doses of ASP2151 under fasted condition in healthy male subjects.
- Trial name
- NCT02852876
- Testing
- ASP2151
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe Ltd.
Herpes Zoster, Neuralgia
NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is determine if an investigational drug, NGX-4010 (high-concentration capsaicin dermal patches) is effective in treating pain associated with post-herpetic neuralgia (PHN).
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00061776
- Testing
- Capsaicin Dermal Patch
- Where
- 28 sites in United States
- Volunteers
- 300 people
- Sponsor
- NeurogesX