Clinical trials: Varicose Vein
Venous Leg Ulcer (VLU)
Assessing Sensor-Guided Compression Therapy for Venous Leg Ulcers Healing Outcomes
The investigators are conducting a study to find out if a new system can help improve the care of people with venous leg ulcers (VLU).
- Trial name
- NCT07268482
- Testing
- A connected-health, pressure-sensing system for monitoring sub-bandage pressure during compression therapy
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Feeltect Limited
Venous Ulcer, Allograft
Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration
Does the use of decellularised dermis allograft in addition to compression therapy promote healing in chronic venous leg ulceration compared to compression therapy alone
- Trial name
- DAVE (NCT04021316)
- Testing
- dCELL® Human Dermis (decellularised dermal skin allograft - DCD), Compression bandaging therapy
- Where
- 17 sites in United Kingdom
- Volunteers
- 71 people
- Sponsor
- Imperial College London
Vascular Diseases, Peripheral, Venous Insufficiency of Leg
The Study of Reducing Adverse Effects After Radiofrequency Ablation Combined With Sclerotherapy
The purpose of this study is to evaluate whether adding sulodexide to the patients with varicose veins who received radiofrequency ablation combined with sclerotherapy can reduce or improve the impact of adverse events。
- Conditions
- Vascular Diseases, Peripheral, Venous Insufficiency of Leg, Varicose Veins of Lower Limb
- Trial name
- NCT05654233
- Testing
- Sulodexide
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Cirrhosis, Portal Vein Thrombosis
Safety of Anticoagulant Therapy After Endoscopic Treatment
The investigators aimed to verify the efficacy and safety of nadroparin calcium warfarin sequential (NWS) anticoagulation therapy after endoscopic therapy in PVT patients with cirrhosis and AVB.
- Conditions
- Cirrhosis, Portal Vein Thrombosis, Esophageal and Gastric Varices, Anticoagulant-induced Bleeding
- Trial name
- NCT04976543
- Testing
- nadroparin calcium-warfarin sequential anticoagulation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Qilu Hospital of Shandong University
Variceal Bleeding
Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal Bleeding
The administration of Vitamin K1 (Vit-K1) injection is frequently utilized in clinical practice for managing upper gastrointestinal bleeding (UGIB) associated with liver cirrhosis, despite insufficient evidence supporting its…
- Trial name
- NCT06839352
- Testing
- Vitamin K1
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Venous Ulcers
Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
This study will test the safety and efficacy of nitric oxide gas in the treatment of venous leg ulcers
- Trial name
- NCT00545298
- Testing
- Nitric Oxide - same dose 6 wks, Nitric Oxide modified treatment
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Nitric BioTherapeutics, Inc
Gastric Varix
Endoscopic Ultrasound-guided Coil With Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration in Managing Patients With Gastric Varices
Gastrointestinal bleeding is a common complication of liver cirrhosis which caused by esophageal and gastric varices. The risk of bleeding from gastric varices is relatively low.
- Trial name
- NCT05500625
- Testing
- Endoscopic ultrasound-guided coil embolization combined with endoscopic cyanoacrylate injection, Ballon-occluded retrograde transvenous obliteration
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diabetic Foot Ulcer, Venous Leg Ulcer
Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds
The purpose of this survey is to observe the efficacy and safety of EPIFIX® dehydrated human amnion/chorion membrane (DHACM) for the treatment of intractable diabetic foot ulcers or venous leg ulcers.
- Trial name
- NCT06236750
- Testing
- EPIFIX
- Where
- 5 sites in Japan
- Volunteers
- 75 people
- Sponsor
- MiMedx Group, Inc.
VARICOSE VEINS
Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate In The Superficial Varicose Veins Treatment
Evaluate the safety, tolerability and effectiveness of mucopolysaccharide polysulfate in the treatment of superficial varicose veins
- Trial name
- NCT01203397
- Testing
- TOPIC MUCOPOLYSACCHARIDE POLYSULFATE 5MG/G
- Where
- Brazil
- Sponsor
- EMS
Varicose Veins
Optimum Duration of Compression Stockings After Endovenous Varicose Vein Surgery
Compression stockings are traditionally worn for a period of time after varicose vein surgery to reduce pain and bruising. The investigators provide an ambulatory endovenous ablation service.
- Trial name
- NCT02676908
- Testing
- Compression socks for 2 weeks
- Where
- Ireland
- Volunteers
- 110 people
- Sponsor
- St. James's Hospital, Ireland
Varicose Veins
Long-term Ultrasound Guided Foam Sclerotherapy Versus Classical Surgical Stripping Study
The aim of this study is to investigate the long-term follow-up of the previously conducted FOAM study.
- Trial name
- NCT02304146
- Where
- 3 sites in Netherlands
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Venous Disorder, Varicose Veins Leg
Prolonged Compression Following Foam Sclerotherapy
Foam-form sclerotherapy is an effective method for eliminating varicose veins, which can be used alone or in combination with other interventions (laser or radiofrequency ablation, cyanoacrylate glue embolization) in the…
- Trial name
- ProCOMFFS (NCT06766968)
- Testing
- Graduated Compression Stocking: 1 month using, Graduated Compression Stocking: 1 week using
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- Pirogov Russian National Research Medical University
Venous Ulcer
Effectiveness of XCell on Autolytic Debridement of Venous Ulcers
This clinical trial is designed to evaluate the effect of XCell cellulose wound dressing for its ability to naturally (autolytically) remove nonviable tissue and create a healthy vascular wound bed.
- Trial name
- XCell (NCT00446823)
- Testing
- XCell cellulose wound dressing, Impregnated gauze dressing
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xylos Corporation
Varicose Veins
Radio Frequency Ablation Versus Stripping of Great Saphenous Vein in Management of Primary Varicose Veins , Comparative Study
Varicose veins are one of the most common diseases worldwide it constitutes a progressive disease which during its course it produces complications that usually prompt the patient to seek medical care.
- Trial name
- NCT05342779
- Testing
- stripping of great saphenous vein
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Varicose Veins of Lower Limb, Varicose Veins and Edema of Leg
Effects of Kinesio Taping Method on Functional Capacity and Quality of Life in Patients With Chronic Venous Disease
The purpose of this randomised and controlled study is to investigate the effects of Kinesio Taping method and compression stockings, combined with exercise therapy, on pain, edema, functional capacity and quality of life in…
- Conditions
- Varicose Veins of Lower Limb, Varicose Veins and Edema of Leg, Chronic Venous Hypertension Peripheral, Spider Veins
- Trial name
- NCT04148950
- Testing
- Kinesio Tape, Compression Stockings, Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Istanbul University
Diabetic Foot Ulcers, Venous Ulcers
Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds
This study will examine differences in the process of wound-healing in patients treated with platelet rich plasma (a concentration of proteins derived from a patients own blood) applied to the wound as a gel; injected into the…
- Conditions
- Diabetic Foot Ulcers, Venous Ulcers, Pressure Ulcers
- Trial name
- CMS (NCT02071979)
- Testing
- Autologous PRP Gel, Autologous PRP Injections, Autologous PRP Gel plus PRP Injections
- Where
- 6 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Arteriocyte, Inc.
Varicose Veins of Lower Limb
Subfascial Endoscopic Perforator Surgery (SEPS) Versus Open Ligation for Lower Limb Varicose Veins
The goal of this study is to compare two surgical treatments for lower limb varicose veins: subfascial endoscopic perforator surgery (SEPS) and open perforator ligation.
- Trial name
- SEPS (NCT07872150)
- Testing
- Subfascial Endoscopic Perforator Surgery(SEPS), Open Perforator Ligation(Stab Avulsion)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- King Edward Medical University
Acute and Chronic Wounds, Pressure Ulcers
Clinical Evaluation of the SNaP Wound Care System
The purpose of this study is to assess the efficacy of design improvements of the Spiracur SNaP Wound Care System. This study prospectively evaluates the safety and efficacy of current and new design iterations of components of…
- Conditions
- Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers
- Trial name
- NCT01113658
- Testing
- SNaP Wound Care System
- Where
- 2 sites in United States
- Sponsor
- 3M
Venous Ulcer
Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers
The purpose of this study is to compare the effectiveness of standard venous ulcer care to standard venous ulcer care plus a cell based product made from the patients own blood.
- Trial name
- NCT00273234
- Testing
- Autologous Platelet Gel (APG)
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Healing Corporation
Compensated Advanced Chronic Liver Disease
Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)
Compensated advanced chronic liver disease (cACLD) commonly indicates severe fibrosis and compensated cirrhosis at risk of developing clinically significant portal hypertension (CSPH) and hepatic decompensation.
- Trial name
- NCT05100485
- Testing
- Esophagogasrtoduodendoscopy, Hepatic venous pressure gradient
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province