Clinical trials: Varicose Vein Disease
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Varicose Veins
Radio Frequency Ablation Versus Stripping of Great Saphenous Vein in Management of Primary Varicose Veins , Comparative Study
Varicose veins are one of the most common diseases worldwide it constitutes a progressive disease which during its course it produces complications that usually prompt the patient to seek medical care.
- Trial name
- NCT05342779
- Testing
- stripping of great saphenous vein
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Varicose Veins, Venous Reflux
Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent
The aim of this study is to identify whether the treatment of pelvic venous reflux (pelvic embolisation) in females with recurrent leg varicose veins, who have a proven contribution to their leg varicose veins from pelvic venous…
- Conditions
- Varicose Veins, Venous Reflux, Pelvic Congestion Syndrome
- Trial name
- NCT01909024
- Testing
- Coil embolisation, endovenous treatment of leg recurrent varicose veins
- Where
- 2 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- The Whiteley Clinic
Varicose Veins, Veins Diseases
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
This is a one-arm, open label, prospective, single center study to evaluate clinical standardization with Theraclion's Sonovein 2 HIFU device.
- Conditions
- Varicose Veins, Veins Diseases, Varicose Ulcer
- Trial name
- NCT04280679
- Testing
- Sonovein 2
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Theraclion
Venous Insufficiency
Comparison of Treatments in Venous Insufficiency
Randomized controlled trial, a method used to implement the random allocation sequence is numbered containers. The aim of the study is to compare operative treatment, ultrasound guided laser ablation and ultrasound guided foam…
- Trial name
- NCT01298908
- Testing
- Operative treatment, Laser ablation, Foam sclerotherapy
- Where
- 2 sites in Finland
- Volunteers
- 231 people
- Sponsor
- Helsinki University Central Hospital
Diabetic Foot Ulcer, Venous Leg Ulcer
Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers
The purpose of this study is to determine how well multiple CAMPs (Cellular, Acellular and Matrix-Like Products) and Standard of Care work when compared to Standard of Care alone in achieving complete closure of diabetic foot and…
- Trial name
- CAMPLIFE (NCT06562296)
- Testing
- Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 292 people
- Sponsor
- Cellution Biologics
Venous Leg Ulcers, Venous Leg Ulcers (VLUs)
Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs
The purpose of this study is to evaluate the efficacy of two dehydrated human umbilical cord-based medical devices, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in…
- Conditions
- Venous Leg Ulcers, Venous Leg Ulcers (VLUs), Venous Leg, Leg Ulcers
- Trial name
- CORDSTIM-VLU (NCT07449988)
- Testing
- Standard of Care (SOC), Corplex P, Theracor
- Volunteers
- 272 people
- Sponsor
- StimLabs
Venous Ulcers
Effect of Hyaluronic Acid ECM on Venous Ulcers
The purpose of this pilot study is to compare the incidence and rate of wound healing in subjects with venous ulcers treated with an extracellular matrix composed of hyaluronic acid plus compression therapy as compared to…
- Trial name
- NCT02930499
- Testing
- Hyalomatrix extra-cellular matrix, Mepilex wound dressing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Calvary Hospital, Bronx, NY
Wounds, Wound of Skin
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up.
- Conditions
- Wounds, Wound of Skin, Wound Leg, Wound; Foot
- Trial name
- NCT05588583
- Testing
- Mepilex Up
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Molnlycke Health Care AB
Varicose Veins, Venous Reflux
High Intensity Focused Ultrasound in PAtients With Varicose Veins in Singapore
The aim of the study is to evaluate the efficacy of non-invasive echotherapy for the treatment of varicose veins, within local population, using the Sonovein® device.
- Conditions
- Varicose Veins, Venous Reflux, Chronic Venous Insufficiency
- Trial name
- VESPA (NCT04339088)
- Testing
- Questionnaires
- Where
- Singapore
- Volunteers
- 15 people
- Sponsor
- Singapore General Hospital
Ulcer Venous, Ulcer Foot
Efficacy of a New Composition (BU002) for Debridement of Chronic Cutaneous Ulcers
This study is testing a new liquid treatment for people with long-lasting (chronic) wounds, such as venous leg ulcers or diabetic foot ulcers.
- Trial name
- NCT07607106
- Testing
- BU002, Polyhexanide 0.1% and betaine 0.1% gel
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Universidad del Desarrollo
Venous Insufficiency
Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins
This trial is designed as a prospective, non randomized, single center clinical trial to determine the safety and efficacy of laser ablation of incompetent perforator veins.
- Trial name
- RELIEVE (NCT00565604)
- Testing
- Short Catheter Delivery
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions LLC
Varicose Veins
A Comparison of Specialized Versus Standard Compression After Saphenous Ablation
The purpose of this study is to determine if the use of specialized compression garments, in comparison to standard compression, improves early patient outcomes after endovenous ablation.
- Trial name
- NCT01332838
- Testing
- Compression stockings, compression stockings (Sigvaris )
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Lymphocele, Varicose Veins
Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report
A 48-year-old female presented to the plastic surgery outpatient department (OPD) with a history of painful, progressive swelling of the right groin and medial aspect of the right thigh for 4 months.
- Trial name
- NCT05398458
- Testing
- Lymphocele excision and space obliterated by pedicle Gracilis muscle only flap
- Where
- Pakistan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bahria International Hospital
Leg Ulcer, Varicose Ulcer
Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
This pilot study was designed to test the safety of Celaderm(TM) in treating venous leg ulcers and to give preliminary information about the efficacy of two different Celaderm(TM) dosing regimens.
- Trial name
- NCT00399308
- Testing
- Celaderm (Frozen Cultured Epidermal Allograft), Control (compression bandaging)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Shire
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Varicose Veins
Treatment of Great Saphenous Vein Varicosities
Venous insufficiency at lower extremities may result in clinical problems from cosmetic issues to ulcerations. When the frequency of venous insufficiency and its related problems are considered besides their diversity, it is…
- Trial name
- NCT05655416
- Testing
- Endovenous chemical ablation with Trendelenburg's operation (eCAT)
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Al-Azhar University
Venous Leg Ulcer, Wound Healing
FORCEREPAIR - A Wound Exudate Investigation
The observational longitudinal study will collect wound exudate from twenty patients with venous leg ulcers. Wound exudate samples are collected using twenty-four-hour collection with polyurethane foam, bandages and the NovaSwab…
- Conditions
- Venous Leg Ulcer, Wound Healing, Non-healing Wound, Cytokines
- Trial name
- NCT06109844
- Testing
- Standard of Care
- Where
- 2 sites in Denmark
- Volunteers
- 13 people
- Sponsor
- Bispebjerg Hospital
Artificial Intelligence
AI-assisted Gastroscopic Varicose Vein Diagnosis
Validation of the accuracy of AI in assisting gastroscopic varices diagnosis through a prospective multicenter study
- Trial name
- NCT05293457
- Where
- China
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Esophageal Varices, Non-alcoholic Fatty Liver
Non-invasive Prediction of Esophageal Varices in Patients With Non-Alcoholic Fatty Liver Disease With Advanced Fibrosis
Non-alcoholic fatty liver disease (NAFLD) is defined as accumulation of fat in the liver which is not related to either alcohol excess or other causes such viral infection, immune-mediated, or medication related which can lead to…
- Conditions
- Esophageal Varices, Non-alcoholic Fatty Liver, Compensated Cirrhosis
- Trial name
- NCT05485714
- Testing
- Reviewing records retrospectively of patients undergoing screening endoscopy
- Where
- United Arab Emirates
- Volunteers
- 73 people
- Sponsor
- United Arab Emirates University