Clinical trials: Varicose Vein Disease
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Varicose Ulcer
Educational Intervention to Promote Compression Therapy in People With Venous Ulcer
Background: Chronic Venous Disease (CVD) is a condition that affects a significant percentage of the world's population, and can range from mild symptoms such as telangiectasias to severe manifestations such as venous ulcers…
- Trial name
- NCT06812520
- Testing
- Educational intervention in adherence
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Alide Salazar Molina
Venous Ulcer
Community RCT of the Effectiveness of Two Compression Bandaging Technologies
Leg ulcers are emotionally distressing and painful, and often require months or years to heal. Although rarely acknowledged as a pressing health care issue, leg ulcers comprise a common, complex, and costly condition, managed…
- Trial name
- NCT00202267
- Testing
- Four-layer Bandage (Elastomeric), Short-stretch Bandage (Non-elastomeric)
- Where
- 15 sites in Canada
- Volunteers
- 426 people
- Sponsor
- Queen's University
Venous Insufficiency, Leg Ulcer
The Evaluation of OrCel for the Treatment of Venous Ulcers
This study was designed to confirm the clinical benefits and safety of OrCel in the treatment of venous ulcers. OrCel and standard care are compared to standard care alone.
- Trial name
- NCT00270972
- Testing
- Bilayered Cellular Matrix (OrCel)
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Ortec International
Varicose Veins
Hypnoanalgesia in Surgical and Endovenous Treatment of Varicosis
Endoveinous treatment of saphenous varicoses and phlebectomia of tributary veins are commonly performed under local anesthesia. Hypnoanalgesia might reduce perinterventional pain.
- Trial name
- NCT03601572
- Testing
- No intervention
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Venous Insufficiency, Oedema
REVITIVE for the Treatment of Patients With Venous Insufficiency
To investigate the efficacy of an electrical stimulation (using the REVITIVE IX device) in treating patients with venous insufficiency.
- Conditions
- Venous Insufficiency, Oedema, Varicose Veins
- Trial name
- RVI (NCT02114307)
- Testing
- REVITIVE IX
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
Venous Stasis, Deep Venous Thrombosis
Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis
In this study we are going to measure the blood flow in the lower limbs under cast immobilisation and also under mobilisation with an orthosis.
- Trial name
- NCT03420664
- Testing
- Orthosis VACOped, Below knee cast
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Varicose Veins of Lower Limb
Ongoing Registry of Treatment of Chronic Venous Diseases
Ongoing registration of patients with varicose veins disease treated by means of conventional surgery, endovenous thermal ablations, sclerotherapy, non-tumescent non-thermal methods
- Trial name
- RRT CVD (NCT03035747)
- Testing
- conventional surgery, endovenous laser ablation, sclerotherapy
- Where
- Russia
- Volunteers
- 5,000 people
- Sponsor
- Medalp Private Surgery Clinic
Chronic Venous Insufficiency
Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein
The aim of this study is to perform a randomized, prospective trial comparing the two current methods of treatment for chronic venous insufficiency, in an effort to evaluate complications and outcomes for each method, and…
- Trial name
- NCT02236338
- Testing
- Ablation of the Incompetent Greater Saphenous Vein, ClosureFAST radiofrequency catheter, EVLT 980nm diode laser system
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Virginia Commonwealth University
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® pH Point of Care Wound Diagnostic Test
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
- Trial name
- NCT04614038
- Testing
- DETEC® pH
- Where
- 2 sites in United States
- Volunteers
- 450 people
- Sponsor
- Progenitec Inc.
Venous Ulcer
Juxta-CuresTM Versus Bandaging for Venous Ulcers
Venous ulceration is a major burden on the NHS. Current treatment involves bandaging therapy which is replaced on a once or twice weekly basis.
- Trial name
- Juxta-Cures (NCT02790593)
- Testing
- Juxta-Cures™, Standard Compression, PicoPress®
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Colchester Hospital University NHS Foundation Trust
Leg Ulcers, Diabetic Foot Ulcer
Vacuum Compression Therapy for Chronic Lower Limb Ulcers
The goal of this clinical trial is to learn if vacuum compression therapy added to standard care improves wound healing in adults with chronic lower limb ulcers.
- Conditions
- Leg Ulcers, Diabetic Foot Ulcer, Varicose Ulcers, Skin Ulcer
- Trial name
- NCT07737184
- Testing
- Vacuum Compression Therapy (VCT), Standardized Wound Care
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- BTL Industries Ltd.
Venous Thromboses, Venous Disease
The GORE® VIABAHN® FORTEGRA Venous Stent Post-Approval Study
This study is a prospective, multicenter, single-arm post-market clinical study to evaluate the GORE® VIABAHN® FORTEGRA Venous Stent in real-world use.
- Conditions
- Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
- Trial name
- NCT07538609
- Testing
- GORE® VIABAHN® FORTEGRA Venous Stent
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- W.L.Gore & Associates
Venous Leg Ulcer (VLU), Chronic Wound
Smart Bandage With Telemonitoring vs Standard Care for Venous Leg Ulcer: Randomized Trial
Venous leg ulcers (VLUs) are chronic wounds that are often slow to heal and can greatly affect patients' daily lives. This study will evaluate a new "smart bandage" that can monitor wound conditions such as pH, temperature, and…
- Trial name
- SMART-VLU (NCT07163195)
- Testing
- Smart Bandage with Telemonitoring, Conventional Bandage
- Where
- Indonesia
- Volunteers
- 110 people
- Sponsor
- Asmat Burhan
Varicose Veins, Superficial Venous Thrombosis
Comparison of Daytime Surgery in Varicose Veins Patients With and Without Superficial Venous Thrombosis
Varicose veins of lower extremities are the most common disease in vascular surgery, and daytime surgery has gradually become the mainstream of varicose veins of lower extremities.
- Conditions
- Varicose Veins, Superficial Venous Thrombosis, Day Surgery
- Trial name
- NCT05380895
- Where
- China
- Volunteers
- 699 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Chronic Venous Insufficiency, CVI
The Use of Immersive Virtual Reality as a Method of Treating Anxiety and Procedural Pain During Endovenous Laser Ablation (EVLA) of Lower Varicose Veins Under Tumescent Anesthesia
This is a prospective, single-arm, pre-post interventional study designed to evaluate the feasibility, safety, and impact of immersive virtual reality (VR) as an adjunct to tumescent local anesthesia during endovenous laser…
- Trial name
- EVLA+VR (NCT07624929)
- Testing
- VR (VR-Control)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Bydgoszcz University of Science and Technology
Varicose Veins
Microwaves Ablation of Varicose Veins
Lower-limb varicose veins (VVs) are the most common of vascular diseases and affect up to one-third of the population, severely affecting the quality of life (QoL) of patients.
- Trial name
- NCT05508581
- Testing
- microwaves ablation of varicose veins
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Chronic Leg Ulcer, Venous Leg Ulcer
Safety and Tolerability of Single and Multiple Doses of SoftOx Biofilm Eradicator (SBE) in Chronic Leg Wounds
Single-centre clinical study investigating the safety and tolerability of randomised, double-blinded, placebo-controlled ascending single doses of topically applied SoftOx Biofilm Eradicator (SBE) in patients with chronic leg…
- Trial name
- NCT05710094
- Testing
- SoftOx Biofilm Eradicator (Groups 1 to 7), Sterile isotonic saline (Groups 1 to 4)
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- SoftOx Solutions AS
Varicosity
Elastic Compression in Chronic Venous Disease
Patients with chronic venous disease causing pain or ache will be randomised into two groups, active stockings (18-21 mmHg) or placebo stockings
- Trial name
- RECVEN (NCT02641600)
- Testing
- Elastic stockings
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Patras
Varicose Veins
Comparison of Radiofrequency, Vein Stripping and CHIVA for Venous Insufficency
Randomized controlled clinical trial aimed to compare the effectiveness and safety of radiofrequency, saphenous vein stripping and conservative hemodynamic treatment of venous insufficiency (CHIVA) in the treatment of saphenous…
- Trial name
- NCT02454452
- Testing
- Radiofrequency, Saphenous vein stripping, CHIVA
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Corporacion Parc Tauli