Clinical trials: Varicose Vein Disease
Varicose Veins, Venous Reflux
A Singapore Venaseal Real World Post-Market Evaluation Study
The study aims to assess the efficacy of VenaSeal™ Closure System (VCS) for the treatment of lower extremity superficial truncal veins in a real-world clinical setting, in a multi-racial Asian population in Singapore.
- Conditions
- Varicose Veins, Venous Reflux, Chronic Venous Insufficiency
- Trial name
- ASVS (NCT03893201)
- Testing
- Questionnaires
- Where
- 2 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- Singapore General Hospital
Venous Insufficiency, Leg Ulcer
THERMES ET VEINES: Spa for Prevention of Leg Ulcers
The main objective of this study is to test the hypothesis that a 3 week intensive course of spa therapy can reduce the risk of leg ulcers in patients with advanced chronic venous insufficiency (C4a-b and C5 of the CEAP…
- Conditions
- Venous Insufficiency, Leg Ulcer, Varicose Ulcer
- Trial name
- NCT00838500
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 425 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Diabetic Foot, Venous Ulcer
Adipose Derived Regenerative Cellular Therapy of Chronic Wounds
Our study aims to explore the effects of Adipose Derived Stem Cells (ASCs) on chronic wounds.
- Conditions
- Diabetic Foot, Venous Ulcer, Pressure Ulcer
- Trial name
- NCT02092870
- Testing
- Adipose derived stem cells
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Tower Outpatient Surgical Center
Varicose Veins
Efficacy of the SALFOAM 3% Method Compared to the Conventional Polidocanol Foam Method (Tessari Method) for Treating Lower Limb Varicose Veins
This clinical trial aims to assess the efficacy and safety of the SALFOAM 3% method, which involves saline wash, polidocanol 3% foam injection, and extrinsic compression using Lidstop®, in comparison with the conventional Tessari…
- Trial name
- SALFOAM 3% (NCT06667570)
- Testing
- SALFOAM 3%, Control Group
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Lidiane Rocha
Venous Leg Ulcer, Varicose Ulcer
Laser Therapy for Venous Leg Ulcers
This randomized controlled trial will evaluate the effects of high-intensity laser therapy on wound healing in patients with venous leg ulcers.
- Conditions
- Venous Leg Ulcer, Varicose Ulcer, Stasis Ulcer
- Trial name
- NCT06135246
- Testing
- High Intensity Laser Therapy, Standard Care
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ahram Canadian University
Varicose Veins
A Study of Soundscapes for Patient Wellbeing
The purpose of this study is to assess the impact of immersive soundscape on patient pain, stress, anxiety, heart rate and blood pressure during an outpatient vascular surgery procedure.
- Trial name
- NCT05650073
- Testing
- Immersive soundscapes
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Mayo Clinic
Venous Leg Ulcer
Electrostimulation in Patients with Leg Ulcers
Abstract Evaluate the effect of transcutaneous electrical nerve stimulation on proinflammatory cytokines, angiogenic and growth factors in subjects with venous ulcers of the lower extremities.
- Trial name
- NCT06849024
- Testing
- Transcutaneous electrical neurostimulation
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Centro Universitario de Tonalá
Cirrhosis, Varices
Baveno VI Criteria in Dynamic Monitoring of High-risk Varices in Compensated Cirrhotic Patients
Patients meet Baveno VI criteria (with a liver stiffness <20kPa and with a platelet count >150,000 are considered to have very low risk of having varices requiring treatment, but whether these patients can be followed up by…
- Conditions
- Cirrhosis, Varices, Non-invasive Evaluation
- Trial name
- CHESS2204 (NCT05538546)
- Testing
- Complete blood count, Transient elastrography, Endoscopy
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
Venous Leg Ulcer, Venous Ulcer
Evaluation of the Efficacy of Multilayer Compression & UrgoStart Plus
Historically, venous leg ulcers have been very difficult to manage, with associated poor healing rates, and the likelihood of recurrence.
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Insufficiency of Leg, Leg Ulcer
- Trial name
- NCT06007703
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Lymphocele, Varicose Veins
Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report
A 48-year-old female presented to the plastic surgery outpatient department (OPD) with a history of painful, progressive swelling of the right groin and medial aspect of the right thigh for 4 months.
- Trial name
- NCT05398458
- Testing
- Lymphocele excision and space obliterated by pedicle Gracilis muscle only flap
- Where
- Pakistan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bahria International Hospital
Estrogen Excess, Varicose Veins
Estrogen Receptors and Chronic Venous Disease
Chronic Venous Disease (CVD) is a very common problem affecting western adult population. To date the pathophysiology of CVD development encloses several theories such as the role of extracellular matrix (ECM) components…
- Trial name
- ERCVD (NCT02558426)
- Testing
- Venous Surgery
- Volunteers
- 40 people
- Sponsor
- University of Catanzaro
Varices; Cord
Outcome of Sub-inguinal Varicocelectomy on Normal Semen in Patients Complaining of Orchilagia With Normal Semen
varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not.
- Trial name
- NCT03835143
- Testing
- subinguinal varicocelectomy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Varicose Veins, Wound Infection
A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery
To investigate whether Betadine can reduce infection rates and recurrence rates following varicose veins surgery in a randomized double blind placebo controlled study.
- Conditions
- Varicose Veins, Wound Infection, Recurrence
- Trial name
- NCT00500669
- Testing
- Betadine
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Hobart Hospital
Venous Disease
Perforator Vein Injection for Symptomatic Venous Disease
The primary objective of this study is to compare two treatment strategies for symptomatic venous stasis disease with and without venous ulcer. These treatments are compression therapy alone vs.
- Trial name
- Dillavou (NCT03363633)
- Testing
- sodium tetradecyl sulfate, Compression
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ellen Dillavou
Esophageal and Gastric Varices, Liver Cirrhosis
Decompression Intervention of Variceal Rebleeding Trial (DIVERT)
The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center prospective randomized clinical trial comparing the radiologic procedure of transjugular intrahepatic portal-systemic shunt (TIPS) with the…
- Trial name
- NCT00006161
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Distal Splenorenal Shunt
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Varicose Vein
Effect of Intensive Sports Practice on Lower Limb Varicose Veins
Compare the frequency of varicose veins in the lower limbs in a population exposed to intensive sport compared to individuals matched by sex, age and body mass index (BMI) did not have an intensive sport.
- Trial name
- VARISPORT (NCT02846051)
- Testing
- venous mapping
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Varicose Ulcer
Effectiveness and Efficiency of Two Models of Delivering Care to a Chronic Wound Population
Individuals referred to home care for leg ulcer management were randomized to nurse home visits (usual care) or nurse-run community clinics (intervention). The primary outcome will be the time to healing rates at three months.
- Trial name
- NCT00656383
- Testing
- Clients randomized to nurse-led clinic, Clients receive leg ulcer care in their homes
- Where
- 2 sites in Canada
- Volunteers
- 401 people
- Sponsor
- Queen's University
Compression; Vein, Patient Satisfaction
Patients Commitment to Compression Therapy
The study Patients Commitment to compression therapy (POMP) is observational, prospective. After the Phlebologist consultation after 1 month and 1 year, a telephone questionnaire is carried out for the patients included in the…
- Trial name
- POMP (NCT04096729)
- Testing
- compression stockings
- Where
- 2 sites in Belarus
- Volunteers
- 400 people
- Sponsor
- Belarusian State Medical University
Venous Thromboses, Venous Stasis
Evaluation of the OsciPulse Rapid Cycling Compression Device Effects on Venous Blood Flow
This study will evaluate the effects on venous blood flow of the investigational device, OsciPulse system, which is an external intermittent limb compression device.
- Trial name
- NCT05087108
- Testing
- OsciPulse system, Reference Therapy 1, Refence Therapy 2
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- OsciFlex LLC