Clinical trials: Varicose Vein Disease
Varicose Veins
LivRelief Varicose Veins Cream in the Treatment of Varicose Veins
Phase IV interventional design where all participants used the test product as per package instructions for 6-weeks. Baseline observations were compared to those collected after 6-weeks of treatment.
- Trial name
- NCT03653793
- Testing
- Natural Health Product: LivRelief Varicose Veins Cream
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Delivra, Inc.
Varicose Veins, Chronic Venous Insufficiency
The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression
Technically successful laser crossectomy will reduce the risk of reflux recurrence at the sapheno-femoral junction without increasing the risk of endovenous heat-induced thrombosis, which may positively impact the likelihood of…
- Trial name
- LACROSS-VVP (NCT07449728)
- Testing
- Laser crossectomy on 1470 nm, Laser crossectomy on 1940 nm, Standard EVLT with a stump
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Pirogov Russian National Research Medical University
Venous Insufficiency, Leg Ulcer
THERMES ET VEINES: Spa for Prevention of Leg Ulcers
The main objective of this study is to test the hypothesis that a 3 week intensive course of spa therapy can reduce the risk of leg ulcers in patients with advanced chronic venous insufficiency (C4a-b and C5 of the CEAP…
- Conditions
- Venous Insufficiency, Leg Ulcer, Varicose Ulcer
- Trial name
- NCT00838500
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 425 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Skin Ulcer Venous Stasis Chronic
Clinical Trial to Investigate Efficacy and Safety of the IMP in Patients With Non Healing Wounds Originating From Ulcers
The aim of this clinical trial is to investigate the efficacy (by monitoring the wound size reduction) and safety (by monitoring occurring adverse events) of the investigational medicinal product APZ2 after one single application…
- Trial name
- NCT02742844
- Testing
- APZ2 application
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- RHEACELL GmbH & Co. KG
Ulcer, Venous Ulcer
ECM and Blood Components for Wound Healing
The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound…
- Conditions
- Ulcer, Venous Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT01909908
- Testing
- ECM, Blood Products, ECM in Blood Products
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Leg Ulcers, Venous Ulcers
Physical Activity Interventions for Leg Ulcer Patients
The goal of this study is to test FOOTFIT and enhanced FOOTFIT+, home-based mobile health (mHealth) physical activity (PA) interventions for a minimally ambulatory, chronically-ill, population with leg ulcers.
- Conditions
- Leg Ulcers, Venous Ulcers, Varicose Ulcers
- Trial name
- FOOTFIT (NCT02632695)
- Testing
- FOOTFIT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Varicose Ulcer
Preliminary Testing of New Treatment for Chronic Leg Wounds
Most chronic (long-lasting) wounds of the leg (also known as venous ulcers) fail to heal in a reasonable period of time. Although researchers have made great progress in understanding how the body repairs wounds, attempts to…
- Trial name
- NCT00000431
- Testing
- PDGF-B/Ad5
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Wounds and Injuries, Burns
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
The proposed registry Sponsor (Siddhey LLC) will collect data on various wound treatments in real life settings. Data collection will facilitate the analysis of the safety and efficacy of wound treatments.
- Conditions
- Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed
- Trial name
- SIDDX (NCT06328010)
- Testing
- Various types of wound care treatments
- Where
- 12 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Siddhey LLC
Venous Leg Ulcer
A Study in Patients With Venous Leg Ulcers and Measuring the Effects of Using Geko™ Device
This is a single centre open label study measuring lower limb physiology in patients with venous leg ulcers at the University Hospital of South Manchester.
- Trial name
- NCT02884323
- Testing
- geko™ device
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Firstkind Ltd
Venous Leg Ulcer
Effect of rhGM-CSF on the Healing of Venous Leg Ulcers
The objective of this study is to examine whether local administration of the growth factor rhGM-CSF incorporated into a hydrogel, can accelerate wound healing when applied to venous leg ulcers, and whether this is safe.
- Trial name
- NCT04823962
- Testing
- rhGM-CSF + hydrogel, Standard care
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Reponex Pharmaceuticals A/S
Venous Leg Ulcer
Helium Neon Laser Versus Gallium Arsenide Laser
There will be different effects for different laser wavelengths in treatment of venous ulcer.
- Trial name
- NCT04689620
- Testing
- laser
- Volunteers
- 60 people
- Sponsor
- Mahmoud Awad Ramadan Elkholy
Chronic Venous Insufficiency
Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins
Part I: Proof of concept trial to achieve normal venous pressure values under different provocation maneuvers in healthy persons Part II: Non invasive measurement of venous pressure under different provocation maneuvers in…
- Trial name
- NCT01000909
- Testing
- Ultrasound (venous pressure measurement)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Liver Cirrhosis, Liver Fibrosis
Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of GOV in Patients With cACLD
A observational diagnostic study will be conducted to compare the performance of liver stiffness and spleen stiffness measured by 2D-shear wave elastography (2D-SWE) and transient elastography (TE) for diagnosing gastroesophageal…
- Conditions
- Liver Cirrhosis, Liver Fibrosis, Portal Hypertension
- Trial name
- NCT06144437
- Testing
- Transient elastography (TE) and 2D-shear wave elastography (2D-SWE)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Varicose Veins of Lower Limb
Varicose Veins in Petrol Pump Workers
To check the prevalence of varicose veins among petrol pump workers
- Trial name
- NCT07071805
- Where
- Pakistan
- Volunteers
- 323 people
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Varicose Veins
Surgery Versus Sclerotherapy for Isolated Accessory Great Saphenous Vein Varicosis
The purpose of this study is to compare two therapeutic procedures in the treatment of isolated varicosis of the anterior accessory great saphenous vein (AAGSV): crossectomy and avulsion of the varicose AAGSV versus foam…
- Trial name
- NCT02010723
- Testing
- surgery, sclerotherapy with aethoxysclerol foam
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Varicose Veins, Veins Diseases
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
This is a one-arm, open label, prospective, single center study to evaluate clinical standardization with Theraclion's Sonovein 2 HIFU device.
- Conditions
- Varicose Veins, Veins Diseases, Varicose Ulcer
- Trial name
- NCT04280679
- Testing
- Sonovein 2
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Theraclion
Diabetic Foot Ulcer
DermACELL in Subjects With Chronic Wounds of the Lower Extremities
The study will compare treatment with DermACELL to conventional care in diabetic foot ulcers (DFU) and venous stasis ulcers (VSU).
- Trial name
- NCT01970163
- Testing
- DermACELL, GraftJacket, Conventional Care Dressings
- Where
- 12 sites in United States
- Volunteers
- 202 people
- Sponsor
- LifeNet Health
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer
CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations
CAMP RWE Trial: A Multicenter hybrid platform trial comparing the effects of a prospective cohort treated with a tri-layer amnion graft or a single layer amnion graft to a coarsened exact matched retrospective control cohort of…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer, Wound; Foot
- Trial name
- CAMP RWE (NCT07046767)
- Testing
- IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap, IP2: BioLab Tri-Membrane Wrap
- Where
- 7 sites in United States
- Volunteers
- 165 people
- Sponsor
- Capsicure, LLC
Diabetic Foot Ulcer, Venous Leg Ulcer
Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC
The purpose of this study is to compare Pellograft to standard of care modalities in treating diabetic foot ulcers in human subjects, and to compare Sanograft to standard of care in treating venous leg ulcers.
- Trial name
- NCT06515093
- Testing
- PelloGraft, SanoGraft
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Surgenex
Venous Thrombosis
The GORE Viabahn Endoprosthesis for the Treatment of Venous Occlusions and Stenoses
To study the safety and efficacy of drug coated stents for the treatment of venous occlusions and stenoses in the lower extremity.
- Trial name
- NCT01406795
- Testing
- Gore Viabahn Heparin Coated Stent
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University