Clinical trials: Varicose Veins of Lower Limb
Varicose Veins of Lower Limb
Subfascial Endoscopic Perforator Surgery (SEPS) Versus Open Ligation for Lower Limb Varicose Veins
The goal of this study is to compare two surgical treatments for lower limb varicose veins: subfascial endoscopic perforator surgery (SEPS) and open perforator ligation.
- Trial name
- SEPS (NCT07872150)
- Testing
- Subfascial Endoscopic Perforator Surgery(SEPS), Open Perforator Ligation(Stab Avulsion)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- King Edward Medical University
Venous Ulceration
A Study of Risk Factors for Venous Ulceration in Patients With Varicose Veins of Lower Extremities.
Varicose veins of lower extremities can lead to adverse consequences such as ulceration and hemorrhage, which seriously endangering the physical and mental health and quality of life for patients.
- Trial name
- NCT05519176
- Where
- China
- Volunteers
- 1,234 people
- Sponsor
- Yibing Wang
Pressure Ulcer, Diabetic Foot Ulcer
An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds
An open, non-comparative, multicenter investigation to evaluate the safety and performance of Exufiber Ag+, a gelling fiber silver dressing, when used in medium to high exuding chronic wounds
- Conditions
- Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
- Trial name
- NCT05494450
- Testing
- ExufiberAG+
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Molnlycke Health Care AB
Venous Leg Ulcer (VLU)
A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance and Safety of a Soft Silicone Foam Dressing and to Evaluate the Performance of Standard Care in Exuding Venous Leg Ulcers
This investigation is a Post Marketing Follow-Up Study for Mepilex XT conducted as part of Mölnlycke Health Care's quality system.
- Trial name
- NCT02167815
- Testing
- Mepilex XT, standard care
- Where
- 3 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Molnlycke Health Care AB
Venous Ulcer
Juxta-CuresTM Versus Bandaging for Venous Ulcers
Venous ulceration is a major burden on the NHS. Current treatment involves bandaging therapy which is replaced on a once or twice weekly basis.
- Trial name
- Juxta-Cures (NCT02790593)
- Testing
- Juxta-Cures™, Standard Compression, PicoPress®
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Colchester Hospital University NHS Foundation Trust
Ulcer, Venous Ulcer
ECM and Blood Components for Wound Healing
The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound…
- Conditions
- Ulcer, Venous Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT01909908
- Testing
- ECM, Blood Products, ECM in Blood Products
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Venous Ulcers
Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
The purpose of this study is to determine whether nitric oxide (NO)gas is effective in the treatment of venous ulcers of the lower leg.
- Trial name
- NCT00613808
- Testing
- Nitric Oxide 200ppm Group B
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Nitric BioTherapeutics, Inc
Pain, Leg Edema
is Ultrasound-guided Foam Sclerotherapy a Cost-effective Alternate for Treatment of Varicose Veins?
. It is the aim of this paper is to discuss our experience of foam sclerotherapy for varicose veins atour hospital
- Conditions
- Pain, Leg Edema, Cost Effectiveness, Cosmesis
- Trial name
- NCT04655417
- Testing
- Sodium Tetradecyl Sulfate
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Venous Leg Ulcers
A RCT Evaluating Efficacy of Type-I Collagen Skin Substitute vs. Human Amnion Membrane in Treatment of Venous Leg Ulcers
Venous leg ulcers are chronic wounds caused by venous insufficiency, leading to significant morbidity. The purpose of this randomized, controlled study is to evaluate the safety and efficacy of the application of Type-I…
- Trial name
- NCT06831760
- Testing
- SOC and Type-I Collagen-based Skin Substitute, SOC and Human Amnion/Chorion Membrane
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr Naveen Narayan MS, MCh (Plastic Surgery)
Venous Leg Ulcer
Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating venous leg ulcers.
- Trial name
- NCT06930768
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Varicose Veins of Lower Limb, Venous Insufficiency of Leg
Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous Varicose Veins
Objective: To investigate the clinical efficacy of ultrasound-guided radiofrequency ablation and microwave ablation in the treatment of primary saphenous varicose veins.
- Conditions
- Varicose Veins of Lower Limb, Venous Insufficiency of Leg, Vascular Disease，Peripheral
- Trial name
- NCT06711120
- Testing
- Radiofrequency ablation and microwave ablation are used to treat small saphenous varicose veins, respectively
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Venous Leg Ulcer
Early Venous Reflux Ablation Ulcer Trial
The EVRA study evaluates the effects of early endovenous ablation on ulcer healing in patients with chronic venous ulceration. Half the patients are randomised to receive early endovenous ablation (within 2 weeks) and half to…
- Trial name
- EVRA (NCT03286140)
- Testing
- Early endovenous ablation, Delayed endovenous intervention
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- Imperial College London
Venous Leg Ulcer
PLASOMA Efficacy & Technology Health (PETH) Study
This study is designed to examine beneficial effects of PLASOMA treatment compared to the standard of care on chronic venous leg ulcers (VLU) that match the size of the plasma area of the pad.
- Trial name
- NCT04922463
- Testing
- PLASOMA
- Where
- 2 sites in Netherlands
- Volunteers
- 46 people
- Sponsor
- Plasmacure
Venous Leg Ulcer
Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
This study randomly assigns patients with venous leg ulcers to receive standard therapy (compression) alone or compression plus Dermagraft(R).
- Trial name
- DEVO (NCT00909870)
- Testing
- Dermagraft(R), Profore
- Where
- 70 sites in United States, Austria and 6 more
- Volunteers
- 537 people
- Sponsor
- Organogenesis
Varicose Veins of Leg With Long Saphenous Vein Distribution, Varicose Veins of Lower Limb
Mechanochemical Ablation Versus Ultrasound-Guided Foam Sclerotherapy of the Great Saphenous Vein
This study compares two minimally invasive treatments for varicose veins in the legs, specifically the great saphenous vein. Varicose veins can cause symptoms such as leg pain, swelling, and skin changes.
- Trial name
- NCT07561320
- Testing
- Flebogrif, Polidocanol foam sclerotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Antonio Eduardo Zerati
Venous Ulcer
Randomized Controlled 8-week Crossover Evaluation of Compression Bandage Systems for Venous Leg Ulcers
The purpose of this study is to evaluate the product performance of a new 2-layer compression bandage for the treatment of venous leg ulcers.
- Trial name
- NCT00301496
- Testing
- Coban 2 Layer Compression System
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Hemorrhoid, Hemorrhoidal Disease
Nimsai Herbal for Grade 2-3 Hemorrhoids: A Quadruple-Blind Placebo-Controlled Mechanistic Trial
This randomized, quadruple-blind, placebo-controlled clinical trial evaluates the efficacy and safety of Nimsai Herbal, a proprietary oral phytotherapeutic formulation, in 50 participants aged 18-70 years with endoscopically…
- Trial name
- NAJ2 (NCT07669662)
- Testing
- Nimsai Herbal
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Nimsai Academia
Venous Stasis, Deep Venous Thrombosis
Effects of External Leg Compression Devices on Healing and Blood Clotting
This study aims to compare two different external calf compression devices applied in healthy individuals. These devices are commonly used in medical care in order to prevent the formation of blood clots, for example during…
- Conditions
- Venous Stasis, Deep Venous Thrombosis, Healing Wound
- Trial name
- NCT03050671
- Testing
- Intermittent Pneumatic Compression, Rapid, Intermittent Pneumatic Compression, Slow
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Venous Insufficiency of Leg, Venous Leg Ulcer
Non Contrast MRI in Lower Extremity
We collected retrospectively the non contrast MRI in chia yi memorial hospital for different venous disease of lower extremity morphology and flow ananlysis were done.
- Conditions
- Venous Insufficiency of Leg, Venous Leg Ulcer, Venous Occlusion, Contrast Media Reaction
- Trial name
- NCT04995432
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer
CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations
CAMP RWE Trial: A Multicenter hybrid platform trial comparing the effects of a prospective cohort treated with a tri-layer amnion graft or a single layer amnion graft to a coarsened exact matched retrospective control cohort of…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer, Wound; Foot
- Trial name
- CAMP RWE (NCT07046767)
- Testing
- IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap, IP2: BioLab Tri-Membrane Wrap
- Where
- 7 sites in United States
- Volunteers
- 165 people
- Sponsor
- Capsicure, LLC