Clinical trials: Vascular
Peripheral Arterial Disease, Vascular Disease, Peripheral
Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System
Prospective, multi-center, single-arm study of the M5+ Peripheral IVL system to treat calcified peripheral arteries.
- Trial name
- Disrupt PAD+ (NCT04585763)
- Testing
- Shockwave Medical M5+ Peripheral Intravascular Lithotripsy (IVL)
- Where
- 8 sites in United States, Australia and 1 more
- Volunteers
- 37 people
- Sponsor
- Shockwave Medical, Inc.
Vascular Lesion, Pigmented Lesions
Evaluation of Safety and Efficacy of IPL Presets for Cutaneous Lesions
Single-center, Prospective, Open-Label with Before-After Study Design. Each subject will receive up to three (3) consecutive treatments at 1-month interval.
- Trial name
- NCT05630690
- Testing
- IPL with smart diagnostic handpiece
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Vascular Lesion, Pigmented Lesions
Safety and Efficacy Evaluation of SMART Camera Treatment Presets for Cutaneous Lesions Using IPL
Multi-center, Prospective, Open-Label with Before-After Study Design. Each subject will receive a single treatment. Treatment presets will be determined by the SMART Camera system and approved by the physician.
- Trial name
- NCT05755139
- Testing
- IPL with smart diagnostic handpiece
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Vascular Infections
Vascular No-React Graft Against Infection
This study seeks to demonstrate the effectiveness and safety of the Non-valved Conduit for CE marking on the basis of infection.
- Trial name
- VASC-REGAIN (NCT04031001)
- Testing
- No-React Non-valved Conduit
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Vascular Access Device Complications
Radial Access for Abdominopelvic Vascular Intervention
To evaluate the safety and efficacy of R.A.V.I.(radial access for abdominopelvic vascular intervention), and evaluate the feasibility and safety of repeated radial artery intervention
- Trial name
- NCT05956860
- Testing
- abdominopelvic vascular intervention through the radial artery access
- Where
- China
- Volunteers
- 1,143 people
- Sponsor
- Zhongda Hospital
Vascular Lesion, Pigmented Lesions
Image Data Collection Using a Multi-spectral Camera for Computer Vision Algorithms Research and Development
This is an observational, single-center, open-label photography evaluation. Any patient that arrives for consultation or treatment at the clinic, presenting the required lesions detailed in the protocol can be included.
- Trial name
- NCT05674149
- Testing
- camera
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Microcystic Lymphatic Malformation, Combined Vascular Malformation
Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations
Lympho-vascular malformations result from errors in embryologic vasculogenesis involving capillaries, veins, arteries, lymphatics, or a combination of these.
- Conditions
- Microcystic Lymphatic Malformation, Combined Vascular Malformation, Vascular Malformations
- Trial name
- NCT06160739
- Testing
- Sirolimus 1Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Peripheral Vascular Diseases and Presentation in Patient With Autoimmune Diseases
Prevalence of Peripheral Vascular Diseases and Presentation in Patients With Autoimmune Diseases
Rheumatic autoimmune diseases include conditions such as systemic lupus rheumatoid arthritis systemic sclerosis in which connective tissues are frequently targeted.
- Trial name
- NCT06169865
- Testing
- cross sectional study
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Hossam Adly Mohamed
Patellofemoral Pain Syndrome, Vascular Occlusion
Muscle Training With and Without Vascular Occlusion of Women With Patellofemoral Pain Syndrome: A Random Clinical Trial
Introduction: The treatment of Patellofemoral Pain Syndrome (PFPS) uses the strengthening of the knee and hip muscles. Studies propose the use of partial vascular occlusion (OVP) of the quadriceps muscle to increase muscle…
- Trial name
- NCT04478422
- Testing
- Muscle strengthening with vascular occlusion, Conventional muscle strengthening
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Christiane Macedo
Vascular Access Complication, Coronary Artery Disease
Distal Radial Access for Coronary Procedures
Distal radial access (DRA) in the anatomical snuffbox (AS) is a relatively novel approach that can be considered an alternative to trans radial access (TRA) for coronary procedures.
- Conditions
- Vascular Access Complication, Coronary Artery Disease, STEMI, Non STEMI
- Trial name
- DISTAL (NCT06165406)
- Testing
- Distal radial access
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Hospital Arnau de Vilanova
Stroke, Cerebrovascular Stroke
General Anesthesia for Endovascular Thrombectomy; A Pilot Study.
This study evaluates the outcomes of stroke patients treated for intravascular thrombectomy, using either a local anesthetic with sedation, or a general anesthetic.
- Conditions
- Stroke, Cerebrovascular Stroke, Brain Ischemia, Brain Diseases
- Trial name
- NCT02639806
- Testing
- Sevoflurane, Lidocaine
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Saskatchewan
Diabetes Mellitus, Vascular Complications
Peripheral Vascular REactivity and Muscular Oxygenation in Diabetes Mellitus
Oxygen is required for an optimal muscle function. In patients with diabetes mellitus, hyperglycemia can cause vascular complications.
- Conditions
- Diabetes Mellitus, Vascular Complications, Mitochondrial Diseases
- Trial name
- PREMOD (NCT04226820)
- Testing
- examination: blood pressure assessment, examination: Flow Mediated Dilatation (FMD)-test, examination: handgrip exercise test with Near infrared spectroscopy (NIRS)-monitoring
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Vascular Dilation, Arterial Stiffness
Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females
Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males.
- Trial name
- NCT05221905
- Testing
- BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Ischemic Stroke, Vascular Diseases
Schlaganfallkonsortium Rhein-Neckar (Stroke Consortium Rhine-Neckar)
FAST is an investigator-initiated multicenter study embedded in a German multistate acute stroke network. The main objectives of the FAST study are to improve outcomes and quality of care for stroke patients, to quantify the…
- Conditions
- Ischemic Stroke, Vascular Diseases, Cardiovascular Diseases
- Trial name
- FAST (NCT03157934)
- Testing
- not applicable (observational study)
- Where
- Germany
- Volunteers
- 12,000 people
- Sponsor
- University Hospital Heidelberg
Peripheral Arterial Disease, Peripheral Vascular Diseases
The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD
Peripheral arterial disease (PAD) is a highly prevalent and costly condition. Intermittent claudication (IC), defined as ischemic leg pain that occurs with walking, results in functional impairment, reduced daily physical…
- Trial name
- NCT05036213
- Testing
- BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Virginia
Peripheral Vascular Disease (PVD), Peripheral Arterial Disease (PAD)
A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries.
A prospective randomized trial designed to compare the efficacy and safety of spot stent system versus self-expanding peripheral stent system in the endovascular treatment of femoropopliteal arterial stenotic disease.
- Trial name
- NCT05246410
- Testing
- Spot stent system, Self-expanding peripheral stent system
- Where
- 2 sites in China
- Volunteers
- 196 people
- Sponsor
- Acotec Scientific Co., Ltd
Congenital Heart Disease, Fontan Operation
The Role of the Pulmonary Vasculature in the Fontan Circulation
This study aims to explore the structural and functional characteristics of the pulmonary vasculature in adult Fontan patients. Objectives: Determine the effect of pulmonary vasodilatation on indexed cardiac output during…
- Conditions
- Congenital Heart Disease, Fontan Operation, Pulmonary Vascular Resistance, Pulmonary Vascular Remodeling
- Trial name
- NCT02414321
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Critical Limb Ischemia
ACP-01 in Patients With Critical Limb Ischemia
The primary objective of this study is to determine the efficacy and safety of intramuscular injection of ACP-01, comprised of blood-derived autologous ACPs, in subjects with critical limb ischemia who are receiving standard of…
- Trial name
- NCT02551679
- Testing
- ACP-01
- Where
- 19 sites in United States, Canada
- Volunteers
- 67 people
- Sponsor
- Hemostemix
Vascular Diseases
Cognitive Training in Stroke Patients
The study aims to investigate the behavioral effects, neural correlates and functional connectivity of cognitive training in patients with stroke
- Trial name
- NCT03644290
- Testing
- Cognitive training, Control Condition
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Wrinkle, Benign Pigmented Lesions
Post Market Study To Collect Efficacy Data For The Treatment Of Wrinkles With A Radiofrequency Device
The intended use of the RF (radiofrequency) device used in this study is to assess the efficacy of the handpiece for the treatment of facial wrinkles.
- Conditions
- Wrinkle, Benign Pigmented Lesions, Benign Vascular Lesions
- Trial name
- NCT05096247
- Testing
- TempSure, Icon
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Cynosure, Inc.