Clinical trials: Vascular Access Complication, open to volunteers
Femoral Access Site Closure, Ambulation
Time to Ambulation After ProGlide Closure
Transradial access has become the standard for coronary procedures due to fewer vascular complications and shorter bed rest, yet transfemoral access remains essential for complex peripheral interventions requiring larger sheaths…
- Conditions
- Femoral Access Site Closure, Ambulation, Vascular Access Complication, Vascular Access Site Management
- Trial name
- OPTIMA (NCT07179536)
- Testing
- Ambulation after ProGlide Closure
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Aortic Valve Stenosis, Postoperative Complications
Comparing Suture vs. Combined Closure Strategies for Large Blood Vessel Access in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)
The goal of this clinical trial is to compare two strategies for closing the main artery access site in adult patients undergoing transcatheter aortic valve implantation (TAVI) through a blood vessel in the leg (transfemoral…
- Conditions
- Aortic Valve Stenosis, Postoperative Complications, Vascular System Injuries, Hemorrhage
- Trial name
- SEAL-TAVI (NCT07743697)
- Testing
- Single Suture-Based Vascular Closure Device, Extravascular Collagen Plug-Based Closure Device
- Where
- Switzerland
- Volunteers
- 705 people
- Sponsor
- University Hospital, Basel, Switzerland
Kidney Disease, End-Stage
PATH-03 Paraguay Feasibility Study
The goal of this study is to evaluate the safety and effectiveness of the ePATH system in the creation of an endovascular AVF (endoAVF) in patients who require or will soon require hemodialysis and are eligible for a fistula.
- Trial name
- NCT07034092
- Testing
- ePATH System will be used to create an endoAVF
- Where
- Paraguay
- Volunteers
- 20 people
- Sponsor
- Pathfinder Medical
Transradial Access(TRA), Coronary Angiography (CAG)
Serpentine vs Traditional Hydrophilic Guidewire Tracking in Complex Radial Anatomy
Coronary angiography and angioplasty are commonly performed through the radial artery. In some patients, anatomical variations of the radial and brachial arteries, such as loops, increased tortuosity or sharp angulations may pose…
- Conditions
- Transradial Access(TRA), Coronary Angiography (CAG), Percutaneous Coronary Intervention (PCI), Radial Artery Loop
- Trial name
- S-TRACK (NCT07707427)
- Testing
- Serpentine Technique, Hydrophilic Technique
- Where
- Greece
- Volunteers
- 204 people
- Sponsor
- University Hospital of Patras
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Chatbot-Based Training, Hemodialysis
DialysisBot: AI Chatbot for Hemodialysis Self-Management
End-stage kidney disease requiring hemodialysis is a chronic condition with substantial clinical, functional, and psychosocial burden.
- Conditions
- Chatbot-Based Training, Hemodialysis, Self-management
- Trial name
- NCT07830810
- Testing
- DialysisBot
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Safety and Effectiveness of Midline Catheters, Vascular Access Devices
Evaluating Midline Catheters in Clinical Practice
The goal of this observational study is to learn about the safety and effectiveness of midline catheters in patients who receive midline catheter placement as part of their routine clinical care.
- Trial name
- NCT07677696
- Testing
- Midline catheter placement
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Treatment Outcome, Vascular Access
Reduction of Complications Associated With PICC Management
The present study aims to analyze different care routes of the peripheral access central venous catheter to assess which alternative allows a moderate reduction in the level of complications associated with prolonged care…
- Conditions
- Treatment Outcome, Vascular Access, Vascular Access Device, Vascular Access Complication
- Trial name
- PICC managemen (NCT06944327)
- Testing
- MANAGEMENT CARE, traditional care
- Volunteers
- 460 people
- Sponsor
- Fundacion Miguel Servet
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Dialysis; Complications, Vascular Access Complication
Access Cannulation Trial II
This is a pivotal, interventional, prospective, single-arm, open-label, multi-site clinical investigation intended to support FDA clearance of the study device based on the safety and efficacy of the device in cannulating…
- Trial name
- ACT II (NCT05490225)
- Testing
- VenaSure
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Voyager Biomedical
Diabetic Retinopathy
Artificial Intelligence for Diagnosing Diabetic Retinopathy in Primary Care
This is a clinical trial to evaluate the effects of universal screening for diabetic retinopathy (DR) and diabetic macular edema (DME) using artificial intelligence (AI) in the interpretation of fundus photographs obtained by…
- Trial name
- AID-DR (NCT07236879)
- Testing
- Mobile retinography interpreted by artificial intelligence, Mobile retinography interpreted by ophthalmologists
- Where
- Brazil
- Volunteers
- 922 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Kidney Disease, Hemodialysis Vascular Access
Transforming Hemodialysis-Related Vascular Access Education
The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis…
- Trial name
- THRiVE (NCT05997875)
- Testing
- Educational Materials, Motivational Interviewing, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 360 people
- Sponsor
- University of Pennsylvania
Cancer, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors
The purpose of this randomized clinical trial is to learn if 'complex' cancer patients who receive care guided by a health system intervention, Primary Care Connect (PC2) have their risks of cardiovascular disease (CVD) managed…
- Conditions
- Cancer, Breast Cancer Early Stage Breast Cancer (Stage 1-3), Bladder Cancer, Prostate Cancer (Adenocarcinoma)
- Trial name
- ACCESS-PC (NCT06834204)
- Testing
- PC2: Primary Care Connect
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Rutgers, The State University of New Jersey
ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications
Closed Incision NPWT to Prevent Wound Complications Post-ECMO
Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden.
- Conditions
- ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications, Surgical Site Infection (SSI)
- Trial name
- PREVENT-ECMO (NCT07709546)
- Testing
- Prophylactic Closed-Incision Negative Pressure Wound Therapy, Standard Wound Dressing
- Volunteers
- 144 people
- Sponsor
- St. Antonius Hospital
Amyloidosis, Basal Cell Carcinoma
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it improves treatment satisfaction in cancer patients living in the Florida Panhandle and…
- Conditions
- Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma, Bladder Carcinoma
- Trial name
- NCT07285044
- Testing
- Cancer Therapeutic Procedure, Questionnaire Administration
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Hemodialysis Access, Arteriovenous Fistula
Single-Needle Distal Return for Long-Term Arteriovenous Fistula Care
Background: For millions of people worldwide with kidney failure, a well-functioning vascular access, like an arteriovenous fistula (AVF), is essential for life-sustaining hemodialysis.
- Conditions
- Hemodialysis Access, Arteriovenous Fistula, Arteriovenous Fistula Cannulation, Vascular Access
- Trial name
- NCT07372027
- Testing
- Single-Needle Distal Return (SNDR) Cannulation, Standard Two-Needle AVF Cannulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Hemodialysis Complication, Dialysis Access Malfunction
Six-month Response Rate According to Two Surgical Techniques (Rotational Atherectomy Versus Angioplasty) to Treat Stenosis of Vascular Accesses in Hemodialysis.
A well-functioning hemodialysis vascular access is a decisive factor in the survival of hemodialysis patients, who have a high mortality rate. 85% of these hemodialysis patients, are treated via an arteriovenous fistula (AVF).
- Conditions
- Hemodialysis Complication, Dialysis Access Malfunction, Stenosis
- Trial name
- ARSAV (NCT06868901)
- Testing
- Standard angioplasty + drug-eluting balloon technique, Atherectomy + drug-eluting balloon
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Kidney Disease, Hemodialysis Access
Pivotal Study of the Velocity™ pAVF System
This study will evaluate the Velocity Percutaneous Arteriovenous Fistula (pAVF) System, a new minimally invasive method for creating dialysis access.
- Conditions
- Chronic Kidney Disease, Hemodialysis Access, Arteriovenous Fistula, End Stage Renal Disease (ESRD)
- Trial name
- VENOS-3 (NCT07153939)
- Testing
- Velocity Percutaneous Arteriovenous Fistula
- Where
- 13 sites in United States
- Volunteers
- 126 people
- Sponsor
- Venova Medical
Patient Satisfaction, Vascular Access Complication
Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)
This is a phase IV, prospective, open label, randomized-controlled study that will compare radial access with state-of-the-art femoral access in patients without ST-segment elevation acute myocardial infarction undergoing cardiac…
- Trial name
- REBIRTH (NCT04077762)
- Testing
- Radial Access, State-of-the-art femoral access with 18 gauge needle, State-of-the-art femoral access with 21 gauge needle
- Where
- 6 sites in United States
- Volunteers
- 3,266 people
- Sponsor
- Minneapolis Heart Institute Foundation
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center