Clinical trials: Vascular Complications
Pregnancy Complication, Aortic Dissection
PregnAncy-Related Aortic DISsEction in China
A multicenter observational study on pregnancy-related aortic dissection
- Conditions
- Pregnancy Complication, Aortic Dissection, Marfan Syndrome, Loeys-Dietz Syndrome
- Trial name
- PARADISE (NCT07672210)
- Testing
- Intervention strategies including medication or surgery
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- DeltaHealth Hospital · Shanghai
Transradial Access(TRA), Coronary Angiography (CAG)
Serpentine vs Traditional Hydrophilic Guidewire Tracking in Complex Radial Anatomy
Coronary angiography and angioplasty are commonly performed through the radial artery. In some patients, anatomical variations of the radial and brachial arteries, such as loops, increased tortuosity or sharp angulations may pose…
- Conditions
- Transradial Access(TRA), Coronary Angiography (CAG), Percutaneous Coronary Intervention (PCI), Radial Artery Loop
- Trial name
- S-TRACK (NCT07707427)
- Testing
- Serpentine Technique, Hydrophilic Technique
- Where
- Greece
- Volunteers
- 204 people
- Sponsor
- University Hospital of Patras
Radial Artery Occlusion, Radial Artery Spasm
Radial Access Data in Vascular Interventions Registry
The RADIUS study is a prospective observational registry designed to collect real-world data regarding radial and ulnar artery access in percutaneous vascular interventions.
- Conditions
- Radial Artery Occlusion, Radial Artery Spasm, Vascular Access Complications, Coronary Artery Disease
- Trial name
- RADIUS (NCT07614386)
- Testing
- Radial and Ulnar Artery Access
- Where
- Turkey (Türkiye)
- Volunteers
- 20,000 people
- Sponsor
- Mersin Medicalpark Hastanesi
Hemodialysis Catheter Complication, Catheter Thrombosis
Hemodialysis Catheter Complications in the Emergency Department Versus Hemodialysis Unit
This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency…
- Conditions
- Hemodialysis Catheter Complication, Catheter Thrombosis, Catheter-Related Infections, Hemodialysis Vascular Access
- Trial name
- NCT07645365
- Where
- Turkey (Türkiye)
- Volunteers
- 398 people
- Sponsor
- Antalya Health Sciences University
Haemodialysis, Haemodialysis Complication
Impact of a Tunneled Hemodialysis Catheter With Endexo® Technology on Catheter Dysfunction Compared With Historical Catheter Dysfunction Data in Standard Catheters
There is evidence that central venous catheters made of the permanent and non-eluting integral polymer Endexo® are more resistant to intraluminal thrombosis. This has a direct reducing effect on catheter malfunctions.
- Conditions
- Haemodialysis, Haemodialysis Complication, Vascular Access, Vascular Access Complication
- Trial name
- NCT07655544
- Testing
- Insertion of a tunneled hemodialysis catheter BioFlo Duramax with Endexo® technology (Merit Medical, Utah, USA)
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
End Stage Renal Failure, Hemodialysis, Vascular Access
Comparison of Tunneled Cuffed Dialysis Catheters Versus Arteriovenous Fistulae in Elderly or Multimorbid Patients
Patients are randomly assigned to a study group. Depending on the study group, either an arteriovenous fistula or tunneled cuffed catheter (TCC) will be implanted, followed by continuous evaluation of the patients during the…
- Conditions
- End Stage Renal Failure, Hemodialysis, Vascular Access, Fistulas Arteriovenous, Haemodialysis Complication
- Trial name
- NCT07649083
- Testing
- Tunneled cuffed catheter (TCC) will be implanted for chronic haemodialysis treatment, Arteriovenous fistula creation for chronic haemodialysis treatment
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
Vascular Complications
Prospective Exploration of Vascular Complications Associated With the Use of Immune Checkpoint Inhibitors
The development of immune checkpoint inhibitors (ICIs) has revolutionized the management of many oncological diseases, and their use continues to increase.
- Trial name
- ICI-Vasc (NCT07535944)
- Testing
- Evaluation of the vascular impact of ICIs (Immune Checkpoint Inhibitors)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Hypertensive Disorder of Pregnancy, Pre-Eclampsia
Optimal Blood Pressure Treatment Thresholds Postpartum
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control…
- Conditions
- Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia
- Trial name
- NCT06069102
- Testing
- Usual care, Tight blood pressure control
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Alisse Hauspurg
Lung Protective Ventilation, Cardiopulmonary Bypass
Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery
This study investigates if single lung ventilation on cardiopulmonary bypass can mitigate postoperative lung water accumulation determined by lung ultrasound in the ventilated lung as compared to the non-ventilated lung in…
- Conditions
- Lung Protective Ventilation, Cardiopulmonary Bypass, High-risk Cardiac Patients, Lung Ultrasound
- Trial name
- NCT07612709
- Testing
- Ventilated lung, Non-ventilated lung.
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
Vascular Access Complication, Device Related Infection
Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs)
The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards.
- Conditions
- Vascular Access Complication, Device Related Infection, Device Related Sepsis, Device Site Reactions
- Trial name
- ProP (NCT05741866)
- Testing
- Chlorhexidine gluconate impregnated bordered polyurethane dressing, Standard bordered polyurethane dressing
- Where
- 3 sites in Australia, France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Kidney Failure, Chronic, Peritoneal Dialysis Complication
International (Pediatric) Peritoneal Biobank
Within few years the peritoneal membrane of adult peritoneal dialysis (PD) patients undergoes substantial morphological transformation, including progressive fibrosis, vasculopathy and neoangiogenesis.
- Conditions
- Kidney Failure, Chronic, Peritoneal Dialysis Complication, Transplantation, Healthy
- Trial name
- NCT01893710
- Testing
- biopsy sampling
- Where
- 26 sites in United States, Austria and 13 more
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Vascular Access Complication, Device Related Infection
Chlorhexidine Caps for CLABSI Prevention in Hemodialysis: a Pilot Randomized Controlled Trial
The goal of this clinical trial is to compare a chlorhexidine antimicrobial barrier cap in patients requiring hemodialysis treatment to the standard hemodialysis caps currently used within the Metro North Kidney Health Service.
- Conditions
- Vascular Access Complication, Device Related Infection, Device Related Sepsis, Catheter Infection
- Trial name
- ECHO-HD (NCT07019610)
- Testing
- ClearGuard HD, B Braun Combi-stopper
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- The University of Queensland
Vascular Access Device Complications
Comparing Basilic and Cephalic Vein Approaches for Midline Catheter Placement in Children
This prospective randomized controlled trial aims to compare basilic vein and cephalic vein approaches for midline catheter placement in pediatric patients undergoing general anesthesia.
- Trial name
- NCT07509359
- Testing
- Midline catheter placement via basilic vein, Midline catheter placement via cephalic vein
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Vascular Complications, Supracondylar Humerus Fracture
Management of Vascular Complications in Pediatric Supracondylar Humerus Fractures
To determine the incidence and types of vascular injuries associated with pediatric supracondylar humerus fractures. Identify outcomes of different management strategies Identify risk factors for vascular injury
- Trial name
- NCT07488845
- Testing
- vascular exploration
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Kidney Diseases, End Stage Renal Disease
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a new arteriovenous fistula (AVF) in order to assess the safety and effectiveness of SelfWrap, a…
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Arteriovenous Fistula, Hemodialysis Access Failure
- Trial name
- SAVE-FistulaS (NCT06001827)
- Testing
- SelfWrap Bioabsorbable Perivascular Wrap, Untreated AVF Control
- Where
- 28 sites in United States
- Volunteers
- 600 people
- Sponsor
- VenoStent
Hemodialysis Access, Arteriovenous Fistula
Single-Needle Distal Return for Long-Term Arteriovenous Fistula Care
Background: For millions of people worldwide with kidney failure, a well-functioning vascular access, like an arteriovenous fistula (AVF), is essential for life-sustaining hemodialysis.
- Conditions
- Hemodialysis Access, Arteriovenous Fistula, Arteriovenous Fistula Cannulation, Vascular Access
- Trial name
- NCT07372027
- Testing
- Single-Needle Distal Return (SNDR) Cannulation, Standard Two-Needle AVF Cannulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Femoral Access Site Closure, Ambulation
Time to Ambulation After ProGlide Closure
Transradial access has become the standard for coronary procedures due to fewer vascular complications and shorter bed rest, yet transfemoral access remains essential for complex peripheral interventions requiring larger sheaths…
- Conditions
- Femoral Access Site Closure, Ambulation, Vascular Access Complication, Vascular Access Site Management
- Trial name
- OPTIMA (NCT07179536)
- Testing
- Ambulation after ProGlide Closure
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
End Stage Renal Disease (ESRD), Vascular Access Complication
Autologous Adipose Derived Mesenchymal Stem Cells (AMSC) in Reducing Hemodialysis Arteriovenous Fistula Failure
The aim of this phase 1 study is to determine the role of autologous adipose derived mesenchymal stem cells in the reduction of hemodialysis arteriovenous fistula failure when applied during the time of surgical creation.
- Trial name
- NCT02808208
- Testing
- Single Application of Adipose Derived Mesenchymal Stem Cells (AMSC), Two Applications of Adipose Derived Mesenchymal Stem Cells (AMSC)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Mayo Clinic
Surgery, Post Operative Complications
Enhanced Vitals Monitoring After Major Surgery Trial
The aim of this clinical trial is to examine the feasibility of an enhanced vital sign monitoring solution in-hospital and at-home. This study includes adult patients undergoing inpatient major vascular or abdominal surgery.
- Conditions
- Surgery, Post Operative Complications, Quality of Recovery, General Surgery
- Trial name
- NCT06584825
- Testing
- Enhanced Vitals Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of British Columbia
Vascular Access Complication
Ultrasound vs Veinviewer in Patients With Difficulty IV Access
Patients with difficulty intravenous access frequently have delay of care in emergency departments because Emergency Department (ED) personnel could not establish intravenous (IV) access for diagnostic blood test or treatment.
- Trial name
- NCT02618252
- Testing
- Zonare, Veinviewer
- Where
- United States
- Sponsor
- University of Maryland, Baltimore