Clinical trials: Vascular Conditions
Chronic Urticaria
The Validity, Reliability and Interpretability of Thai-version of Chronic Urticaria Quality of Life Questionnaire
In the majority of patients with the chronic urticaria, the etiology is unclear, leading to difficulties in treatment and high rates of recurrence.
- Trial name
- CU-Q2oL (NCT02285023)
- Testing
- CU-Q2oL
- Where
- Thailand
- Volunteers
- 166 people
- Sponsor
- Mahidol University
Cardiogenic Shock
Viability of Pulsioflex Monitoring in ICU
Goal of the Study is to Study the precision of semi-invasive cardiac index monitoring by means of the ProAQT (PULSION Medical Systems SE) sensor, whereby the pulmonary artery catheter will serve as gold standard.
- Trial name
- NCT04911985
- Testing
- Measurement of the Cardiac Output/ Cardiac Index
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University of Zurich
Necrotizing Pancreatitis
ABTHERA ADVANCE™ Use Without Wittman Patch
The objective of this study is to evaluate the use of the ABTHERA ADVANCE for patients requiring open abdomen due to necrotizing pancreatitis.
- Trial name
- NCT04986943
- Testing
- Using ABTHERA Advance without a Wittmann Patch
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Cardiovascular Diseases, Heart Diseases
Hypertension in Blacks of West African Origin
To continue an international collaborative study on hypertension in populations of West African origin.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005340
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Kidney Disease, Hypertension
ADMA Levels in End-Stage Renal Disease
Asymmetric dimethylarginine, ADMA, in plasma, is significantly elevated in patients with renal disease and associated with cardiovascular morbidity and mortality.
- Trial name
- NCT00350974
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ischemia Reperfusion Injury
Safety and Efficacy of Treprostinil in Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplantation
The overall purpose of this study is to evaluate the safety, pharmacokinetics and preliminary efficacy of a five-days post-operative course of Treprostinil in liver transplant patients.
- Trial name
- NCT01481974
- Testing
- Treprostinil
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Abhinav Humar, MD
Cardiovascular Diseases, Heart Diseases
Strong Heart Study Analyses Obesity and Lipoproteins
To examine the relationship of obesity and body fat distribution to lipoprotein concentrations in members of the Strong Heart Study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Obesity
- Trial name
- NCT00005510
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Parkinson's Disease, Autonomic Neuropathy
Effects of Feet Mechanical Stimulation on Cardiovascular Autonomic Profile and Inflammation in Parkinson's Disease
In the present study, investigators test the hypothesis that a controlled mechanical pressure applied on specific sites of both fore-feet (ES) can reduce the inflammatory state and arterial blood pressure in patients with…
- Conditions
- Parkinson's Disease, Autonomic Neuropathy, Inflammation, Hypertension
- Trial name
- parkgo-1 (NCT02608424)
- Testing
- Foot Mechanical Stimulation (Gondola®, CE marking n° 0476)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
MINOCA
Plaque Burden and Ischemia in MINOCA
The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery…
- Trial name
- NCT05681858
- Testing
- CT coronary angiography and [12N] NH3 PET-MR
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Bergen
Lung Neoplasms, Respiratory Failure
Clearance Of Mucus In Stents (COMIS)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
- Conditions
- Lung Neoplasms, Respiratory Failure, Pneumonia, Acute Coronary Syndromes
- Trial name
- NCT01370278
- Testing
- Normal Saline, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Coronary Artery Disease
Personal Genomics for Preventive Cardiology
The purpose of this study is to see if providing information to a person on their inherited (genetic) risk of cardiovascular disease (CVD) helps to motivate that person to change their diet, lifestyle or medication regimen to…
- Trial name
- NCT01406808
- Testing
- genetic risk score for coronary risk factors
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome
- Trial name
- STEROHCA (NCT04624776)
- Testing
- Methylprednisolone, Isotonic saline
- Where
- 2 sites in Denmark
- Volunteers
- 158 people
- Sponsor
- Christian Hassager
Healthy, Diabetes Type 2
Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness.
The ASI Non-Invasive Arterial Stiffness Screening Device (ASI Device) is an investigational device under development for the non-invasive assessment of arterial stiffness.
- Conditions
- Healthy, Diabetes Type 2, Obesity, Coronary Artery Disease
- Trial name
- ASI-2012 (NCT01722474)
- Testing
- ASI Device
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Myocardial Infarction, Acute Coronary Syndrome
Acute Coronary Syndrome in Patients With COVID-19
The aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, COVID-19, Myocardium; Injury
- Trial name
- ACS-COVID (NCT05732597)
- Testing
- Coronary angiography
- Where
- Bulgaria
- Volunteers
- 26 people
- Sponsor
- Bulgarian Cardiac Institute
Sleep Apnea, Inflammation
PTP1B Implication in the Vascular Dysfunction Associated With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) syndrome is associated with increased vascular dysfunction and atherosclerosis. Especially, it has been shown that OSA associated intermittent hypoxia represents a pro inflammatory stimulus resulting…
- Conditions
- Sleep Apnea, Inflammation, Atherosclerosis
- Trial name
- MacroSAS (NCT04235023)
- Testing
- myeloid PTP1B expression analysis
- Where
- France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Angers
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
Hypertension
Safety/Efficacy of Valsartan/Hydrochlorothiazide Combination Compared to Hydrochlorothiazide in Obese Hypertensive Adults
The purpose of this study is to compare the blood pressure lowering efficacy of valsartan/hydrochlorothiazide (HCTZ) compared to hydrochlorothiazide for the treatment of obese hypertensive (mean sitting systolic blood pressure…
- Trial name
- NCT00439738
- Testing
- HCTZ + Amlodipine, Valsartan/HCTZ
- Where
- 5 sites in United States
- Volunteers
- 412 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Atherosclerosis
Endothelial Dysfunction in Obese Children
The purpose of this study is to objectify the effect of diet and exercise on early markers of atherosclerosis in obese children.
- Trial name
- EDOC (NCT01461226)
- Testing
- Exercise training, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 61 people
- Sponsor
- University Hospital, Antwerp
Myocardial Infarction, Myocardial Injury
Lymphatic Organs and Myocardium After Myocardial Infarction
The adaptive immune response plays an important role in myocardial healing and remodeling after acute myocardial infarction in patients. Therefore, the involved lymphocytes represent a novel target for therapeutic interventions.
- Conditions
- Myocardial Infarction, Myocardial Injury, Myocardial Inflammation
- Trial name
- LOMI (NCT05519735)
- Testing
- Multimodality Imaging
- Where
- 2 sites in Germany
- Volunteers
- 57 people
- Sponsor
- Wuerzburg University Hospital
Obstructive Sleep Apnea of Adult, Hypoxia, Brain
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).
- Conditions
- Obstructive Sleep Apnea of Adult, Hypoxia, Brain, Sleep Apnea, Sleep Disorder
- Trial name
- NCT03255408
- Testing
- Drug Lowering Cerebral Blood Flow (CBF) and Normoxia Sleep, Drug Lowering CBF and Intermittent Hypoxia Sleep
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.