Clinical trials: Vascular Conditions
Diabetes, Diabetes Mellitus
Stanford Clinics Physician Mindset Training
Mindsets play an important role in motivating and shaping health behavior and outcomes. For example, when patients have the mindset that a treatment will work, they are more likely to adhere to treatment medications and the…
- Conditions
- Diabetes, Diabetes Mellitus, Hypertension, Pre Diabetes
- Trial name
- NCT03677609
- Testing
- Mindset & Communication Training
- Where
- United States
- Volunteers
- 78,128 people
- Sponsor
- Kari Alyse Leibowitz
STEMI
Impact of Cardio-Selective Beta-Blockers on Infarct Size After Acute Myocardial Infarction
Introduction: The effect of intravenous beta-blockers on the extent of the necrotic area, after primary percutaneous transluminal coronary angioplasty (PTCA), for acute myocardial infarction is not well established.
- Trial name
- BLOCK-AMI (NCT07293832)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Arterio-venous Fistula
Invasive Arterio-Venous Fistula Blood Pressure Monitoring & Fluid Dynamics Study
The surgical formation of an AVF offers a unique example of vascular remodelling and adaption. Yet, the specific factors which elicit remodelling events which determine successful maturation or failure have not been unambiguously…
- Trial name
- NCT04293614
- Where
- Ireland
- Volunteers
- 12 people
- Sponsor
- University Hospital of Limerick
Ekg Change Ischemia Lateral
Diagnostic Value of Electrocardiographic St-t Wave Changes in Patients With Chronic Stable Angina
The electrocardiogram (ECG) is a simple and non-invasive bedside diagnostic tool with a well-established role in the diagnosis of (CAD).
- Trial name
- ECG (NCT02027506)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Aphasia, Stroke
Can Listening to Music Improve Attention and Language After Post-Stroke Aphasia?
The goal of this clinical trial is to learn if a music-based intervention can acutely improve three types of attention (alerting, orientating, executive control) in people with aphasia following a stroke.
- Conditions
- Aphasia, Stroke, Stroke and Aphasia, Stroke Hemorrhagic
- Trial name
- NCT07198048
- Testing
- Music-Based Therapy for Post Stroke Aphasia, Audiobook Intervention for Post Stroke Aphasia
- Volunteers
- 45 people
- Sponsor
- Purdue University
Smoking Cessation, Cardiovascular Disease
What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?
Introduction: Smoking is a major avoidable cause of ill-health and premature death. Treatments that help patients successfully quit smoking have an important effect on health and life expectancy.
- Conditions
- Smoking Cessation, Cardiovascular Disease, Respiratory Disease, Myocardial Infarction
- Trial name
- NCT02681848
- Testing
- Varenicline, Nicotine replacement therapy
- Volunteers
- 180,000 people
- Sponsor
- University of Bristol
Hypertension, Diet, Mediterranean
Analysis of Bioparametric Measures for Correlating Daily Habits and Reducing Blood Pressure
To study the effects of the use of a mobile application plus recommendations based on a Mediterranean diet on the intake of micronutrients from natural sources (not drugs) on health indicators, cardiovascular parameters (blood…
- Conditions
- Hypertension, Diet, Mediterranean, Cardiovascular Diseases, Exercise
- Trial name
- NCT04828655
- Testing
- Use of a mobile application based on machine learning with the aim of improving health and body composition parameters.
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
Uncontrolled Hypertension, Atrial Fibrillation
Adjunctive Renal Denervation in the Treatment of Atrial Fibrillation
The objective of the H-FIB trial is to determine the role of renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension for whom a catheter-based AF ablation procedure is…
- Trial name
- H-FIB (NCT01635998)
- Testing
- Boston Scientific Vessix Renal Denervation System
- Where
- 8 sites in United States, Czechia and 1 more
- Volunteers
- 50 people
- Sponsor
- Vivek Reddy
Intermittent Claudication
Hospital- and Home-based Supervised Exercise Versus UNsupervised Walk Advice For Patients With InTermittent Claudication
The purpose of this randomized clinical trial is to determine and compare the clinical and cost effectiveness of three methods for exercise therapy as treatment for patients with intermittent claudication.
- Trial name
- SUNFIT (NCT02341716)
- Testing
- WA, SET, HET
- Where
- 2 sites in Sweden
- Volunteers
- 165 people
- Sponsor
- Lennart Jivegård
ST Elevation Myocardial Infarction, Fibrinolysis
Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis
This is a two-center, prospective, randomized, single-blind, investigator initiated, pharmacodynamic study of parallel design, carried out in 2 PCI-capable cardiology centers (Patras University Hospital and Konstantopoulio…
- Conditions
- ST Elevation Myocardial Infarction, Fibrinolysis, P2Y12 Inhibitor
- Trial name
- NCT01950416
- Testing
- Ticagrelor 180mg loading dose and 90mg bid maintenance dose, Clopidogrel 600mg loading dose and 150mg maintenance dose
- Where
- 2 sites in Greece
- Volunteers
- 56 people
- Sponsor
- University of Patras
Hypotension, Point of Care Ultrasound
Sonography in Hypotension and Cardiac Arrest in the Emergency Department.
This study is designed to determine if there is any relationship between performing an abdominal ultrasound on patients who present with hypotension and their clinical outcomes (as measured by 7, 30 day and discharge mortality).
- Conditions
- Hypotension, Point of Care Ultrasound, Shock
- Trial name
- SHoC-ED (NCT01419106)
- Testing
- Ultrasound (A point of care ultrasound protocol)
- Where
- 6 sites in Canada, South Africa
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
Hospital Readmission, Pneumonia
Mobile Integrated Healthcare and Community Paramedicine
Background: Initially conceived of as a method to address healthcare needs of underserved rural populations, Mobile Integrated Healthcare and Community Paramedicine (MIH/CP) is a new model of inter-professional, community-based…
- Conditions
- Hospital Readmission, Pneumonia, Myocardial Infarction, COPD
- Trial name
- NCT05061433
- Testing
- Mobile Integrated Healthcare/Community Paramedicine (MIH/CP) Support
- Volunteers
- 44 people
- Sponsor
- Rhode Island Hospital
Heart Diseases, Cardiovascular Diseases
Acute Cardiac Ischemia in Women in the ACI/TIPI Trial
To conduct a series of five inter-related studies on acute cardiac ischemia (ACI) in women.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Angina Pectoris, Myocardial Ischemia
- Trial name
- NCT00005701
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Ischemic Stroke
Valsartan Efficacy on Modest Blood Pressure Reduction in Acute Ischemic Stroke
The manipulation of blood pressure in acute cerebral ischemia has been a matter of debate until now. The investigators are clearly in need of more detailed data on how antihypertensive treatment affects outcome in acute phase of…
- Trial name
- VENTURE (NCT00874601)
- Testing
- Diovan® (valsartan)
- Where
- South Korea
- Volunteers
- 578 people
- Sponsor
- Hallym University Medical Center
Multiple Myeloma
Melphalan, Prednisone and Thalidomide Versus Melphalan and Prednisone in Elderly Myeloma Patients
The purpose of this study is to determine whether the association of Thalidomide to Melphalan and Prednisone is effective in the treatment of newly diagnosed elderly multiple myeloma.
- Trial name
- NCT00232934
- Testing
- Thalidomide
- Where
- 13 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Gruppo Italiano per lo Studio del Mieloma Multiplo
Rheumatoid Arthritis, Inflammation
Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis
Recent studies show beneficial effect of the inhibition of interleukin-6 (IL-6) activity on vascular and left ventricular (LV) function.
- Trial name
- NCT03288584
- Testing
- Tocilizumab (Actemra®), Other biological agent, Corticosteroid and non-biological agents.
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Hypertension
To Demonstrate the Relative Bioequivalence of Lisinopril 1 x 40 mg Tablets Under Fasting Conditions
To Demonstrate the Relative Bioequivalence of Lisinopril 1 x 40 mg Tablets Under Fasting Conditions.
- Trial name
- NCT00883064
- Testing
- Lisinopril 40 mg Tablet (EON Labs Manufacturing Inc, USA), Lisinopril 40 mg Tablet (Zestril) (Zeneca, USA)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sandoz
Mild Cognitive Impairment, Dementia
Remote Ischemic Conditioning of the Human Brain in Dementia Patients
The study investigates the incidence of remote ischemic conditioning in mild cognitive impairment and dementia patients
- Conditions
- Mild Cognitive Impairment, Dementia, Intermittent Claudication
- Trial name
- RICBDE (NCT04168021)
- Testing
- Leg ischemia
- Volunteers
- 90 people
- Sponsor
- Aristotle University Of Thessaloniki
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