Clinical trials: Vascular Conditions
Myocardial Infarction
Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System
Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters.
- Trial name
- SCARPACE (NCT04757168)
- Testing
- NOGA TM probe
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Chinese PE Multimodality Imaging Artificial Intelligence Study
The CHinese pulmOnary Embolism Multimodality Imaging-artifiCial intelligencE Study (CHOICE) is a prospective observational multi-center study that will collect imaging text data and raw data of patients with pulmonary embolism…
- Conditions
- Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Disease
- Trial name
- NCT06526468
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Low Back Pain
Changes in Blood Flow in the Application of Magnetic Tape in Patients With Low Back Pain. RCT
A tape is applied over the lumbar 4th and lumbar 5th levels crosswise in people with low back pain. The possible variation of the arterial flow of the femoral artery is measured with ultrasound.
- Trial name
- NCT04836468
- Testing
- Tape application
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Francisco Selva
Choroidal Neovascularization (CNV)
Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.
This study was conducted to evaluate the efficacy and safety of 0.5 mg ranibizumab in adult and adolescent patients with visual impairment due to choridal neovascularization (CNV).
- Trial name
- NCT01840410
- Testing
- Ranibizumab
- Where
- 59 sites in Australia, Canada and 19 more
- Volunteers
- 183 people
- Sponsor
- Novartis Pharmaceuticals
Stroke, Ischemic
Neuroprotective Effect of Remote Ischemic Conditioning in Ischemic Stroke Treated With Mechanical Thrombectomy
The benefit of mechanical thrombectomy in the treatment of ischemic stroke has been demonstrated in several multicenter randomized trials.
- Trial name
- PROTECT-I (NCT03915782)
- Testing
- Remote ischemic conditioning
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Hospices Civils de Lyon
Myocardial Infarction, Influenza
The Role of Influenza as a Trigger for Acute Myocardial Infarction: a CALIBER Study
The purpose of this study is to examine the incidence of acute myocardial infarction (MI) occurring after an influenza-like illness using linked primary care and disease registry databases.
- Trial name
- NCT01106196
- Where
- 2 sites in United Kingdom
- Volunteers
- 11,208 people
- Sponsor
- University College, London
Subarachnoid Hemorrhage
S100B Kinetic During the Occurrence and Treatment of Delayed Cerebral Ischaemia After a Subarachnoid Haemorrhage.
Nearly half of the survivors of subarachnoid haemorrhage (SAH) retain irreversible neurological damage resulting from the early lesions associated with the initial bleeding, and the occurrence of possible delayed cerebral…
- Trial name
- SKinDCI (NCT04795362)
- Testing
- blood sample
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Periventricular Leukomalacia, White Matter Disease
Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia
The goal of this study is to explore a new treatment that may help repair brain damage in individuals with periventricular leukomalacia (PVL), a condition that affects white matter in the brain.
- Conditions
- Periventricular Leukomalacia, White Matter Disease, Hypoxic-Ischemic Encephalopathy, Demyelinating Diseases
- Trial name
- NCT06985303
- Testing
- Investigational Combination Product
- Sponsor
- MGAM LLC
Cardiac Surgery
Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgery: a Randomized Controlled Trial
Perioperative neurological complications in cardiovascular surgical procedures are associated with a significant risk of mortality and disability.
- Trial name
- NICE (NCT06791551)
- Testing
- active RIPC and tDCS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Subarachnoid Hemorrhage
Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to determine the effectiveness of prophylactic administration of intra-thecal nicardipine though lumbar cerebrospinal fluid drain in prevention of symptomatic vasospasm in patients with subarachnoid…
- Trial name
- NCT07246629
- Testing
- Normal Saline, Nicardipine
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Wake Forest University Health Sciences
Non-ST-elevation Myocardial Infarction
Thrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI)
Whereas thrombus aspiration in patients with ST-elevation myocardial infarction (STEMI) is recommended by current guidelines, there are insufficient data to unequivocally support thrombectomy in patients with non-STEMI (NSTEMI).
- Trial name
- NCT01612312
- Testing
- Thrombectomy, Standard percutaneous coronary intervention
- Where
- 7 sites in Germany
- Volunteers
- 400 people
- Sponsor
- University of Leipzig
Intracerebral Hemorrhage
Management of Intracerebral Hemorrhage With Aminocaproic Acid - Pilot Study
This is single-arm, open-label, safety and feasibility pilot study of ɛ-aminocaproic acid in ICH patients. Consecutive ICH volume with hematoma volume less than 30 mL by ABC/2 method presenting within 3 hours of symptom onset…
- Trial name
- MANICHAN-PILOT (NCT02639819)
- Testing
- ɛ-Aminocaproic Acid
- Sponsor
- The University of Texas Health Science Center at San Antonio
Coronary Artery Disease, Coronary Artery Angiography
Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization
In a double-blinded randomized clinical trial, all patients undergoing coronary artery catheterization who will met our criteria, will be enrolled into three groups to receive either, vitamin e, n-acetylcysteine, or placebo.
- Conditions
- Coronary Artery Disease, Coronary Artery Angiography, Coronary Catheterization, Contrast-induced Nephropathy
- Trial name
- NCT03755700
- Testing
- Vitamin E, N-acetyl cysteine, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Iran
- Volunteers
- 1,000 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Myocardial Infarction, Anemia
Conservative Versus Liberal Red Cell Transfusion in Myocardial Infarction Trial: The CRIT Pilot
The purpose of this trial is to determine whether a conservative or a liberal blood transfusion strategy is better for patients with a heart attack and a low blood count.
- Trial name
- CRIT (NCT00126334)
- Testing
- Packed Red Blood Cell Transfusion
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Medstar Health Research Institute
Myocardial Infarction
Improving Door-to-Balloon Time in STEMI
The investigators prospectively determined the impact on median door-to-balloon time of a protocol mandating (1) emergency department physician activation of the catheterization lab and (2) immediate transfer of the patient to an…
- Trial name
- EHART (NCT00800163)
- Testing
- ED Activation/Immediate Transfer
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- St. Francis Hospitals & Health Centers
STEMI
Prognostic Value of Lactate Levels in Patients With STEMI Undergoing Primary PCI
To assess the prognostic value of systemic arterial lactate levels in patients with ST segment elevation myocardial infarction undergoing primary PCI and correlate with the results of primary PCI and 30 days MACE follow up.
- Trial name
- NCT05503329
- Testing
- arterial lactate level
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ahmed Maher Teaching Hospital
Hypertension
Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers
The purpose of this study is to evaluate the comparative bioavailability of two fixed dose combination tablet formulations of amlodipine and losartan in healthy volunteers.
- Trial name
- NCT01648231
- Testing
- Reference Treatment: 1 x 5mg amlodipine tablet and 1 x 100mg losartan tablet administered in fasted state, Fixed Dose Combination 1: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state, Fixed Dose Combination 2: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state
- Where
- Australia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Myeloproliferative Disorders, Leukemia
Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
RATIONALE: Giving low doses of chemotherapy, such as fludarabine and busulfan, before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- Bu Flu TBI (NCT00245037)
- Testing
- therapeutic allogeneic lymphocytes, busulfan, cyclosporine
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- OHSU Knight Cancer Institute
Multiple Myeloma
Phase 2 Clinical Trial of NPI-0052 in Patients With Relapsed or Relapsed/Refractory Multiple Myeloma
This is a Phase 2, open-label, multicenter study examining the safety, pharmacokinetics and pharmacodynamics, and best overall response to escalating doses of the proteasome inhibitor NPI-0052 (also known as marizomib) in…
- Trial name
- NCT00461045
- Testing
- MRZ 0.5 mg/m^2
- Where
- 6 sites in United States
- Volunteers
- 15 people
- Sponsor
- Celgene
Multiple Myeloma, Low-Grade Lymphoma
64Cu-LLP2A for Imaging Hematologic Malignancies
This phase of the protocol (protocol part B), seeks to evaluate the new formulation in healthy normal volunteers to confirm the new formulation provides comparable human dosimetry to which was seen and published in protocol part…
- Conditions
- Multiple Myeloma, Low-Grade Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT06636175
- Testing
- 64Cu-LLP2A, PET/CT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.