Clinical trials: Vascular Conditions
Cardiogenic Shock, Short Term Mechanical Circulatory Support
Outcomes in CArdiogenic SHock Patients Treated by MEchanical Circulatory suppoRt devicE : Impact of Shock Team
In this before-after monocenter study, the authors teste the hypothesis that the implementation of a dedicated shock team could improve the outcome of patients with refractory cardiogenic shock assisted by mechanical circulatory…
- Conditions
- Cardiogenic Shock, Short Term Mechanical Circulatory Support, Shock Team
- Trial name
- CASHMERE (NCT05309980)
- Testing
- standard of care
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Bordeaux
Acute Ischemic Stroke AIS
Palmitoylethanolamide and Luteolin in Patients with Acute Ischemic Stroke
Acute ischemic stroke is caused by reduced blood supply to the brain associated with neuroinflammation. This mechanism contributes to acute neuronal death and persists even after reopening of the closed vessel, with consequent…
- Trial name
- NCT06777680
- Testing
- co-ultramicronized Palmitoylethanolamide + Luteolin (770 mg), Thrombectomy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedali Riuniti Trieste
Coronary Artery Disease (CAD)
Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)
Observe whether the administration of caffeine prior to regadenoson will affect the interpretation of test results in subjects with coronary artery disease (CAD) undergoing SPECT MPI
- Trial name
- NCT00826280
- Testing
- regadenoson, overencapsulated caffeine, technetium
- Where
- 25 sites in United States
- Volunteers
- 347 people
- Sponsor
- Astellas Pharma Inc
Venous Leg Ulcer
Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison of the Efficacy and Safety of Two Dressings Urgotul and TulleGras
Evaluation of the non-inferiority of TulleGras M.S.® versus Urgotul® in pain associated with removal of wound dressing during care of venous leg ulcer
- Trial name
- NCT02104180
- Testing
- Urgotul, TulleGras M.S.
- Where
- 27 sites in France
- Volunteers
- 62 people
- Sponsor
- Mylan Inc.
Traumatic Brain Injury
Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT
The purpose of this study is to test an on-line intervention for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01056146)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI, Internet Resources Comparison
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Ventricular Tachycardia
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Data collection registry for patients with ventricular tachycardia to help physicians give better care for patients clinically and procedurally.
- Trial name
- MANAGE-VT (NCT06455488)
- Testing
- Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- CorVita Science Foundation
Stroke, Aphasia
Exploration of Repeated High-frequency Transcranial Magnetic Stimulation for the Treatment of Acute Phase Aphasia in Post-stroke Patients
Stroke is currently an important cause of death and disability among adults worldwide, with acute ischemic stroke being the most common type of stroke, accounting for 69.6% -72.8% of new strokes in China.
- Conditions
- Stroke, Aphasia, Control Patients
- Trial name
- NCT06787508
- Testing
- TMS
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Vision Disorder, Stroke
Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional Study
This cross-sectional observational study aims to characterize acquired visual impairment in adults with acquired brain injury and to examine the relationship between objectively identified visual impairment and self-reported…
- Conditions
- Vision Disorder, Stroke, Brain Injuries
- Trial name
- NCT07858708
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Charles University, Czech Republic
Bleeding, Coagulopathy
Safety and Efficacy Study Comparing Pad-gauze With Anti-fibrinolytic Agent Hemostopan™) to a Regular Pad-gauze
Patients on chronic treatment with hemodialysis have an arterio-venous fistula which enable the insertion of two large gauge needles.
- Trial name
- NCT01854476
- Testing
- pad-gauze with tranexamic acid (Hemostopan™)
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Sion Microtec Ltd.
Cryopyrin-Associated Periodic Syndromes
Kineret CAPS Post Authorisation Study
A non-interventional, post authorization safety study to evaluate the safety of Kineret in the treatment of Cryopyrin Associated Periodic Syndromes (CAPS) in routine clinical care with regard to serious infections, malignancies…
- Trial name
- NCT02326376
- Testing
- anakinra (Kineret)
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 12 people
- Sponsor
- Swedish Orphan Biovitrum
Central Venous Catheter Thrombosis, Critical Illness
Daily Ultrasound-screening for CVC-related Thrombosis
The central venous catheters (CVC) related thrombosis is an issue of importance to ICU clinicians.This study conducts the daily ultrasound-screening for CVC-related thrombosis (DUCT).Its aim is to evaluate the characteristic and…
- Conditions
- Central Venous Catheter Thrombosis, Critical Illness, Ultrasonography
- Trial name
- DUCT (NCT03327376)
- Testing
- ultrasound-screening
- Where
- China
- Volunteers
- 1,262 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pulmonary Embolism
Pulmonary Embolism Diagnosis: Ultrasound Wells Score vs Traditional Wells Score
Pulmonary embolism (PE) should be suspected in patients with dyspnea, chest pain, syncope, shock/hypotension, or cardiac arrest.
- Trial name
- NCT02190110
- Where
- 4 sites in Italy
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Hematologic Neoplasms, Neutropenia
Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies
The purpose of the study is to explore the safety and efficacy of umbilical cord derived mesenchymal stem cells in treatment-induced myelosuppression in patients with hematologic malignancies.
- Conditions
- Hematologic Neoplasms, Neutropenia, Anemia, Thrombocytopenia
- Trial name
- NCT05672420
- Testing
- umbilical cord derived mesenchymal stem cells
- Where
- 3 sites in China
- Volunteers
- 181 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Healthy Participants
A Study to Investigate the Safety, Tolerability and Pharmacodynamics of AZD4144 in Participants With Obesity
The aim of this study is to evaluate the safety and tolerability, and pharmacodynamics (PD) of AZD4144 administered as repeated daily oral dosing.
- Trial name
- NCT06942923
- Testing
- AZD4144
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Stroke, Neglect, Hemispatial
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect).
- Trial name
- SOAR (NCT07331896)
- Testing
- Strategy Training, Attention Control
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Acute Coronary Syndrome
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction. 2.
- Trial name
- NCT02002546
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Coronary Artery Disease
The Effect of Reiki and Acupressure on Pain, Anxiety and Vital Signs
This research aims to determine the effects of reiki and acupressure applied after percutaneous coronary intervention on pain, anxiety and vital signs during femoral catheter extraction.
- Trial name
- NCT05381246
- Testing
- Acupressure, Reiki
- Volunteers
- 84 people
- Sponsor
- Mersin University
Stroke, Respiratory Function
External Diaphragm Pacing Therapy and Correlation Analysis of Trunk Balance and Respiratory Function in Stroke Patients
The goal of this study is to observe the enhancement of trunk balance ability, pulmonary function, and diaphragm function in stroke patients after treatment of external diaphragm pacing（EDP）, and analyze the potential correlation…
- Trial name
- NCT06198946
- Testing
- External diaphragm pacing（EDP）, Routine rehabilitation treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhang liqiong
Coronary Artery Disease, Acute Coronary Syndrome
Personalized Vs. Standard Duration of Dual Antiplatelet Therapy and New-generation Polymer-Free vs- Biodegradable-Polymer DES
New-generation metallic drug-eluting stents represent the standard of care among patients undergoing percutaneous coronary intervention (PCI).
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Chronic Coronary Syndrome, Myocardial Infarction
- Trial name
- PARTHENOPE (NCT04135989)
- Testing
- Percutaneous coronary intervention with implantation of amphilimus-eluting stents for coronary artery disease., Percutaneous coronary intervention with implantation of everolimus-eluting stents for coronary artery disease., Personalized DAPT duration
- Where
- 13 sites in Italy
- Volunteers
- 2,106 people
- Sponsor
- Federico II University
Microvascular Angina, Vasospastic Angina
Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary Arteries
In patients with angina pectoris undergoing a coronary angiography (CAG) up to 40% do not have obstructive coronary artery disease (CAD).
- Trial name
- TENS-ANOCA (NCT06401291)
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
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