Clinical trials: Vascular Conditions
Stroke, Acute, Hemiplegia
Effects of High Frequency rTMS Combined Motor Learning on Upper Limb Motor Function in Subacute Stroke
This study is to present the effect of a program combining high frequency repetitive transcranial magnetic stimulation with motor learning on upper limb motor function and grip strength and activities of daily motion in patients…
- Trial name
- NCT05176613
- Testing
- HF-rTMS, ML
- Volunteers
- 30 people
- Sponsor
- Chungnam National University Sejong Hospital
Endoleak After Endovascular Aneurysm Repair
Multicentre Trial Of Serum Levels Of MMP-9 As A Biomarker Of Endoleak
Endovascular procedures already brought enormous revolution in the process of treatment of patient with abdominal aortic aneurysm (AAA).
- Trial name
- BIOLEAK (NCT01965717)
- Where
- Serbia
- Volunteers
- 65 people
- Sponsor
- Igor Koncar
Stable Angina
Aspirin Resistance and Percutaneous Coronary Intervention (PCI)
The objective of this study is to evaluate if aggressive antiplatelet therapy would reduce ischemic events in aspirin (ASA) resistant patients after percutaneous coronary intervention (PCI).
- Trial name
- RESIST (NCT01103440)
- Testing
- Intravenous Glycoprotein inhibitor + ASA, Clopidogrel, Antiplatelet Therapy (ASA, Clopidogrel)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Coronary Heart Disease, Anemia
The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.
Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors…
- Conditions
- Coronary Heart Disease, Anemia, Bronchial Asthma, Stroke
- Trial name
- STOPRISK (NCT03945968)
- Where
- 38 sites in Russia
- Volunteers
- 16,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Pulmonary Fibrosis
Pilot Study of Pirfenidone in Pulmonary Fibrosis With Anti-myeloperoxydase Antibodies
The purpose of this study is to determine wether pirfenidone is safe and effective in the treatment of pulmonary fibrosis with anti-myeloperoxydase (MPO) antibodies or pulmonary fibrosis with anti-MPO associated vasculitis.
- Trial name
- PIRFENIVAS (NCT03385668)
- Testing
- Pirfenidone
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Abdominal, Hypertension
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
The estrogenic deficit characteristic of the climacteric stage is accompanied by a high incidence of health problems, such as the presence of Metabolic Syndrome risk factors that contribute to the increase of cardiovascular…
- Conditions
- Obesity, Abdominal, Hypertension, Quality of Life, Menopause
- Trial name
- NCT05387174
- Testing
- : Nursing intervention in two risk factors of the Metabolic Syndrome, abdominal obesity and arterial hypertension and quality of life in the climacteric period.
- Where
- Ecuador
- Volunteers
- 80 people
- Sponsor
- Universidad de Concepcion
Myocardial Infarction, Heart Arrest
At-Home Automated External Defibrillator (AED) Training Study
The purpose of the research is to determine the best automated external defibrillator (AED) training approach for high-risk patients and their family members with regard to AED skills retention and psychological adjustment.
- Conditions
- Myocardial Infarction, Heart Arrest, Chest Pain, Congestive Heart Failure
- Trial name
- NCT00219674
- Testing
- Group I: Video training, Group II: Video training + enhanced self-efficacy (SE), Group III: In-person training + enhanced SE
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Public Health - Seattle and King County
Facial Paralysis, Central, Stroke
Mimic Muscle Volume, Central Facial Palsy Severity and Dysphagia
70 stroke patients with central facial paralysis will be included and their demographic data will be questioned and facial nerve thickness, depressor labi inferior, depressor anguli oris, buccinator and risorius muscles will be…
- Trial name
- NCT06615297
- Testing
- ultrasonographic evaluation
- Volunteers
- 70 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Myocardial Infarction
Effects of Intermittent Exercise Training Programs in Patients With Myocardial Infarction
Cardiovascular diseases are a leading cause of death worldwide. According to the World Health Organization (WHO), cardiovascular diseases constitute 1/3 of all causes of death.
- Trial name
- NCT04407624
- Testing
- Intermittent Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Pulmonary Hypertension, Interstitial Lung Disease
A Study of Mosliciguat in PH-ILD
This is a Phase 2, randomized, double-blind, placebo-controlled, multi-center clinical study to evaluate the safety and efficacy of inhaled mosliciguat in participants with pulmonary hypertension associated with interstitial lung…
- Conditions
- Pulmonary Hypertension, Interstitial Lung Disease, Lung Diseases, Vascular Diseases
- Trial name
- PHocus (NCT06635850)
- Testing
- Mosliciguat, Dry Powder Inhaler
- Where
- 85 sites in United States, Argentina and 18 more
- Volunteers
- 135 people
- Sponsor
- Pulmovant, Inc.
Stroke, Brain Injuries
Clinical Effectiveness of iReadMore for People With Alexia
iReadMore will provide an app-based therapy for people with pure or central alexia. This study aims to test the clinical effectiveness of iReadMore for improving reading accuracy and speed in real world users of the therapy.
- Conditions
- Stroke, Brain Injuries, Aphasia, Alexia
- Trial name
- NCT04849091
- Testing
- iReadMore
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally…
- Conditions
- Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage
- Trial name
- ICH03 (NCT05611918)
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University
Multiple Myeloma in Relapse
Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse
Induction therapy approaches in recent years have evolved, now utilizing triple or quadruple drug regimens in the majority of patients.
- Trial name
- NCT06827860
- Testing
- Talquetamab, Daratumumab
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Larysa Sanchez
Sarcoma, Soft Tissue Sarcoma
LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology
Aspirin and low molecular weight heparin (LMWH) are both commonly employed pharmacologic methods of venous thromboembolism (VTE) prophylaxis after orthopaedic surgery.
- Conditions
- Sarcoma, Soft Tissue Sarcoma, Bone Sarcoma, Bone Metastases
- Trial name
- NCT03244020
- Testing
- Aspirin 325mg, Enoxaparin 40Mg/0.4mL Prefilled Syringe
- Where
- 10 sites in United States
- Volunteers
- 2,868 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Myocardial Infarction
Impact of Intracoronary Injection of Autologous BMMC for LV Contractility and Remodeling in Patients With STEMI
This is multicentre, randomised open-label, controlled, parallel-group phase III study. Its aim is to demonstrate that a triple intracoronary infusion of autologous bone marrow-derived mononuclear cells in addition to state of…
- Trial name
- RACE-STEMI (NCT02323620)
- Testing
- Intracoronary infusion of BM-MC
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- American Heart of Poland
Myocardial Reperfusion Injury
Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI
Percutaneous coronary intervention (PCI) for acute coronary syndromes frequently fails to restore myocardial perfusion despite establishing epicardial vessel patency.
- Trial name
- BQ-123 (NCT00586820)
- Testing
- BQ-123
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Stroke, Upper Extremity Paresis
Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke
This study will evaluate the safety and effectiveness of Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) for improving motor recovery after stroke.
- Trial name
- NCT03292159
- Testing
- Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Acute Coronary Syndrome, Sleep Disorder
Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome
The purpose of the study is to examine the effects of Eszopiclone, a sleep aid, on inflammatory mediators and coagulability in patients with a recent myocardial infarction.
- Trial name
- NCT00822679
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Arizona
Urticaria Chronic
Mediterranean and Low-Histamine Diets for Pediatric Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is a chronic inflammatory skin disease that can substantially impair quality of life in children and adolescents.
- Trial name
- NCT07765979
- Testing
- Low-Histamine Diet, Mediterranean Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Saglik Bilimleri Universitesi
Lacunar Strokes
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts
The aim of this study is to determine in patients with a recent lacunar strokes (<15 days), the natural history of cognitive disturbances and disability.
- Trial name
- DHU-LAC (NCT03552926)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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