Clinical trials: Vascular Conditions
Rheumatoid Purpura, Pediatric ALL
Validation of the IgA1 Detection Method With Gradient Glycosylation by Mass Spectrometry as a Potential Marker of Renal Involvement in Pediatric Rheumatoid Purpura
In this ancillary study on the FoxTreg cohort, the study investigators will select variables to input and thus develop two models (Linear Discriminant Analysis and Decision Tree).
- Trial name
- FOXIGA-2020 (NCT04655378)
- Testing
- Mass Sepctrometry
- Where
- 2 sites in France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Cognitive Symptoms
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
Between 1 and 5 percent of patients who have coronary artery bypass surgery suffer a stroke following surgery, and 30 percent have new brain lesions that do not produce symptoms and are seen only on MRI.
- Trial name
- NCT00391378
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Urticaria
Efficacy and Safety Study of Omalizumab (Xolair®) to Treat Chronic Urticaria
Chronic urticaria can be defined as the occurrence of widespread daily or almost daily wheals for at least 6 weeks, which may be accompanied by angioedema.
- Trial name
- NCT01713725
- Testing
- Omalizumab
- Where
- 4 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
STEMI
Efficacy and Safety on Prouk for STEMI Patients in China
The purpose of the study is to evaluate the efficacy and safety of rh-prouk as pharmacoinvasive therapy on those ST Elevated Myocardial Infarctions patients, it is designed as a multicenter, active controlled, single blinded…
- Trial name
- NCT02367976
- Testing
- rhprouk
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Suzhou RxD Biopharmaceutical Co., Ltd
ST-segment Elevation Myocardial Infarction (STEMI)
Impact of Stent Length and Diameter on Patients Undergoing Primary PCI
The goal of the study is to evaluate the Impact of coronary stent length and/or diameter in patients with ST segment myocardial infarction undergoing primary PCI, on Short term clinical outcomes.
- Trial name
- NCT04110691
- Volunteers
- 200 people
- Sponsor
- Assiut University
Long-term Major Cardiovascular Events, Myocardial Infarction
CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction
The purpose of this registry is to evaluate long-term clinical events in patients with acute myocardial infarction who were treated with percutaneous coronary intervention.
- Conditions
- Long-term Major Cardiovascular Events, Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- COREA-AMI (NCT02385682)
- Testing
- Percutaneous coronary intervention
- Volunteers
- 4,748 people
- Sponsor
- Kiyuk Chang
Prediabetic State, Gestational Weight Gain
Healthy Hearts: Leveraging the Diabetes Prevention Program to Decrease Health Disparities in Women of Reproductive Age
Nearly half of women have obesity and/or hypertension (HTN). Specific to women, pregnancy creates a vulnerable window for excess gestational weight gain (GWG), exacerbating intergenerational risks for obesity, HTN, type 2…
- Conditions
- Prediabetic State, Gestational Weight Gain, Hypertension, Overweight or Obesity
- Trial name
- HH (NCT05379296)
- Testing
- Diabetes Prevention Program Plus (DPP+), Diabetes Prevention Program (DPP)
- Sponsor
- The University of Texas Medical Branch, Galveston
Subarachnoid Hemorrhage
Prehospital Deaths From Spontaneous Subarachnoid Haemorrhages
In this study we aim to determine the incidence of fatal spontaneous subarachnoid haemorrhage outside hospital. Also, we aim to investigate these patient´s pattern of contact to the health care system immediately before their…
- Trial name
- NCT04052646
- Testing
- Medical condition: Subarachnoid hemorrhage
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetic Foot Ulcer, Wound
Investigation of the Effects of Different Exercise on Wound Healing in Patients wıth Diabetic Foot Wounds
Diabetic foot ulcers are a common complication of diabetes mellitus and are associated with delayed wound healing, impaired quality of life, and an increased risk of lower extremity amputation.
- Trial name
- NCT05422846
- Testing
- standard treatment, aerobic exercise, exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Harran University
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis
Perception and Multisensory Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in sensory perception and multisensory integration in patients with central or peripheral neurological damage.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, Stroke, Anosognosia
- Trial name
- NCT01469858
- Testing
- Siemens magnetom avanto1.5 Tesla, Siemens magnetom trio A Tim system 3 Tesla
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stroke
The Stroke Box: a Patient-centered eHealth Approach for Improving Post-stroke Care.
Although there have been major advances in (personalized) stroke treatment in the last decade, the need for prevention of stroke remains critical.
- Trial name
- NCT05388578
- Testing
- Blood pressure monitor, Weighting scale, Activity tracker
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Leiden University Medical Center
Hemolysis, Cannulation
Home Hemodialysis Assisted by a Nurse for Arterio-venous Fistula Cannulation
Home HD (HHD) is associated with better outcome in end-stage renal disease patients compared to in-center HD, in particular in terms of quality of life.
- Conditions
- Hemolysis, Cannulation, Arteriovenous Fistula, Nurse's Role
- Trial name
- DIADIDEAL (NCT03633435)
- Testing
- assisted home hemodialysis patients
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Distal Radial Artery Approach, ST Elevation Myocardial Infarction
Comparison of Success Rate Between Distal Radial Approach and Radial Approach in STEMI
ST-segment elevation myocardial infarction (STEMI) is an emergent disease to treat as soon as possible. 2017 ESC guidelines for the management of STEMI recommend using radial approach (RA) rather than femoral approach (FA) to…
- Trial name
- NCT03611725
- Testing
- Distal radial artery, Radial artery
- Where
- 3 sites in South Korea
- Volunteers
- 352 people
- Sponsor
- Wonju Severance Christian Hospital
Diabetic Retinopathy, Retinal Detachment
Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA)
The purpose of this study is to compare the amount of intraoperative intraocular bleeding during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD) with and without preoperative intravitreal…
- Trial name
- IBETRA (NCT00690768)
- Testing
- Bevacizumab, pars plana vitrectomy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Hypoxia-Ischemia, Brain
Development of a High-speed Multimodal Photoacoustic/Ultrasound System for Functional Imaging of the Neonatal Brain
In today's medical field, there is a growing emphasis on the development of functional and molecular imaging. Therefore, it has significant technical limitations.
- Trial name
- NCT06139250
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemia-Reperfusion Injury, Myocardial Infarction
Infusion of a Single Dose of Erythropoietin to Prevent Injury in an Ischemia Reperfusion Forearm Model
Rationale: The investigators hypothesize that EPO protects against apoptosis after acute ischemia in man and that it is detectable using the annexin-A5 model.
- Trial name
- IPIIR (NCT00691613)
- Testing
- Epoetin alpha, NaCl
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill
Angina Pectoris, Myocardial Infarction
GLP-1 Loading During Elective Percutaneous Coronary Intervention
Angina is caused by narrowings or blockages within coronary arteries. Coronary angioplasty and stenting is performed for people with angina to improve the blood supply to the heart by placing metal tubes within the artery using…
- Conditions
- Angina Pectoris, Myocardial Infarction, Reperfusion Injury, Coronary Heart Disease
- Trial name
- GOLD-PCI (NCT02127996)
- Testing
- GLP-1
- Where
- United Kingdom
- Volunteers
- 193 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Moyamoya Disease, Intracranial Hemorrhages
5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya Disease
Intracranial hemorrhage is a leading cause of death and disability in patients with moyamoya disease (MMD), yet clinically available tools for predicting long-term hemorrhage risk are lacking.
- Conditions
- Moyamoya Disease, Intracranial Hemorrhages, Stroke
- Trial name
- NCT07781579
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)
This is a phase 2, Multi-center, double-blind, randomized, placebo-controlled study to evaluate the effects of inhaled Iloprost in patients with pulmonary hypertension secondary to COPD.
- Trial name
- NCT01437878
- Testing
- Iloprost
- Where
- 11 sites in United States, France and 1 more
- Volunteers
- 2 people
- Sponsor
- Actelion
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