Clinical trials: Vascular Conditions
Subarachnoid Hemorrhage, Intracranial Aneurysm
Swiss Study on Subarachnoid Hemorrhage
This registry was created to assess management parameters of patients treated for aneurysmal subarachnoid hemorrhage in Switzerland.
- Trial name
- Swiss-SOS (NCT03245866)
- Testing
- Observational/ no intervention
- Where
- 9 sites in Switzerland
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Geneva
Arterio-venous Fistula
Anchor Versus Parachute Suturing Technique in Arteriovenous Fistula Creation for Hemodialysis
Randomized controlled study to compare the results of two surgical techniques for AVF creation, including the anchor technique (Group A) and parachute technique (Group B).
- Trial name
- NCT06091839
- Testing
- suturing technique in arteriovenous fistula creation for hemodialysis
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Critical Limb Ischemia
Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia
The purpose of this study is to compare the effects (positive and negative) of two different devices available to treat people with critical limb ischemia, which involves a sudden decrease in blood flow to the leg that causes a…
- Trial name
- NCT00869375
- Testing
- Endovascular peripheral intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Oklahoma
Cardiovascular Diseases, Depression
Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors
This study will determine the effects of omega-3 fatty acid (FA) augmentation of sertraline on depression and cardiac endpoints after myocardial infarction (MI).
- Conditions
- Cardiovascular Diseases, Depression, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00116857
- Testing
- Sertraline/omega-3, Sertraline/Corn Oil
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Washington University School of Medicine
Multiple Myeloma
UARK 2014-14: Phase II Prospective Evaluation of Bone Remodeling During Ixazomib Treatment
The purpose of this study is to evaluate the effect of Ixazomib on inducing osteoblast activation as measured by bone markers and imaging in patients with relapsed/refractory myeloma.
- Trial name
- NCT02499081
- Testing
- Ixazomib
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas
Hip Osteoarthritis, Muscle Weakness
The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty
Residual limping after total hip arthroplasty is empirically associated with the use of lateral approach but has been reported in litterature even with the use of posterior approach.
- Conditions
- Hip Osteoarthritis, Muscle Weakness, Muscle Atrophy, Muscle Injury
- Trial name
- HSS (NCT05216666)
- Testing
- Lateral approach, Posterior approach
- Where
- Sweden
- Volunteers
- 580 people
- Sponsor
- Sahlgrenska University Hospital
Mitochondrial Myopathy, MELAS Syndrome
Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia
OBJECTIVES: I. Study the metabolism of pyruvate and related problems in patients with lactic acidemia. II. Define the nature of the metabolic defect.
- Conditions
- Mitochondrial Myopathy, MELAS Syndrome, Lactic Acidosis
- Trial name
- NCT00004353
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Center for Research Resources (NCRR)
Refractory Angina
A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Refractory Angina
The objectives of the study are to assess the safety, tolerability, and potential efficacy of IMB-1018972 on patients with refractory angina.
- Trial name
- NCT04306237
- Testing
- IMB-1018972
- Where
- United States
- Sponsor
- Imbria Pharmaceuticals, Inc.
Critical Limb Ischemia, Infrapopliteal Lesions
Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.
This study was designed to compare excimer laser combined with drug-coated baloons with angioplasty alone in the treatment of infrapopliteal lesions in patients with critical limb ischemia.
- Trial name
- NCT04365075
- Testing
- Excimer Laser Combined with DCB, Angioplasty Alone
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Xuanwu Hospital, Beijing
Rheumatic Diseases, Arthritis
Pain-Sleep in Rheumatic Disease
Overall, our understanding of how pain and sleep are experienced and how they can be treated in teenagers with rheumatic diseases is limited.
- Conditions
- Rheumatic Diseases, Arthritis, Lupus, Lupus Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07775612
- Testing
- Better Nights, Better Days for Youth
- Volunteers
- 43 people
- Sponsor
- The Hospital for Sick Children
Sepsis Associated Disseminated Intravascular Coagulation (DIC)
A Study to Assess the Safety and Effects of Different Doses of an Investigational Drug, BAY 3389934, in Healthy Japanese Volunteers.
This study is designed to evaluate a new investigational drug, BAY 3389934, in healthy Japanese volunteers. The primary purpose is to see how safe the drug is and how well it is tolerated by the body when given at different…
- Trial name
- NCT07176728
- Testing
- BAY 3389934
- Where
- 2 sites in Japan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Bioequivalence
A Pilot Bioequivalence Study of Pomalidomide
Pomalidomide capsule were developed to offer an alternative to the marketed formulation, This pilot study was aim to pre-assess the bioequivalence of the capsule formulations under fasted condition.
- Trial name
- NCT03424928
- Testing
- Pomalidomide 4 MG Oral Capsule, Pomalidomide 4 MG Oral Capsule-Pomalyst
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Acute Myocardial Infarction, Cardiogenic Shock
Low-Dose Dobutamine and Single-Dose Tocilizumab in Acute Myocardial Infarction With High Risk of Cardiogenic Shock
In the present study, we aim to investigate the effects of dobutamine infusion and/or a single intravenous (IV) dose of the IL-6 antagonist Tocilizumab administered after percutaneous coronary intervention (PCI) to patients with…
- Trial name
- DOBERMANN (NCT05350592)
- Testing
- Tocilizumab, Dobutamine, NaCl 0.9%
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypoxic-Ischemic Encephalopathy, Birth Asphyxia
Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries
The investigators will conduct a study on non-vigorous infants at birth to determine if umbilical cord milking (UCM) results in lower rate of moderate to severe hypoxic ischemic encephalopathy (HIE) or death than early clamping…
- Trial name
- CORDMILK (NCT03657394)
- Testing
- Umbilical cord milking
- Where
- 9 sites in India
- Volunteers
- 3,442 people
- Sponsor
- Nemours Children's Clinic
Hypertension, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Neck-to-Waist Ratio Identifies Chronic Hypertensive Phenotype and Occlusive Myocardial Infarction in Patients Presenting With Acute Coronary Syndrome
aim of this study was to evaluate the relationship between multiple conventional and novel anthropometric measurements and hypertension in patients presenting to the ED with ACS and whether anthropometric indices differ according…
- Conditions
- Hypertension, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Obesity (Disorder)
- Trial name
- NCT07676656
- Where
- Turkey (Türkiye)
- Volunteers
- 238 people
- Sponsor
- Ercis Sehit Rıdvan Cevik State Hospital
Ischemic Heart Disease, Myocardial Infarction
Initial Human Validation of Simultaneous Dual-Tracer Cardiac PET Imaging
Positron emission tomography (PET) scans can be used to evaluate whether parts of the heart muscle are alive but receiving inadequate blood supply.
- Trial name
- NCT02003456
- Testing
- Cardiac PET scan w/18F-Fluorodeoxyglucose and rubidium-82
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Stroke, Hemiplegia
Visual and Auditory Electromyography Biofeedback Among Stroke Patients
Stroke commonly results in impairments of balance, mobility, and lower extremity motor function that limit independence in daily activities.
- Conditions
- Stroke, Hemiplegia, Stroke Rehabilitation
- Trial name
- NCT07710937
- Testing
- Visual Electromyography Biofeedback, Auditory Electromyography Biofeedback, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Hypertension, Chronic Kidney Disease
Renal Sympathetic Denervation as a New Treatment for Therapy Resistant Hypertension
The aim of this study is to assess whether renal denervation (RD) added to usual care compared to usual care alone reduces blood pressure (BP) as determined with ambulatory BP monitoring (ABPM) after 6 months in subjects with an…
- Trial name
- SYMPATHY (NCT01850901)
- Testing
- Renal sympathetic denervation
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- UMC Utrecht
DS Stage I Multiple Myeloma, DS Stage II Multiple Myeloma
Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant
This randomized phase III trial studies lenalidomide to see how well it works compared to a placebo in treating patients with multiple myeloma who are undergoing autologous stem cell transplant.
- Conditions
- DS Stage I Multiple Myeloma, DS Stage II Multiple Myeloma, DS Stage III Multiple Myeloma, Refractory Multiple Myeloma
- Trial name
- NCT00114101
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, Laboratory Biomarker Analysis, Lenalidomide
- Where
- 140 sites in United States
- Volunteers
- 460 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Disease, Hypertension
A Pilot Study to Improve Patient-Doctor Communication
The purpose of this controlled pilot study is to determine whether an intervention aimed at patients will improve partnering, shared decision-making and open communication.
- Conditions
- Chronic Disease, Hypertension, Hyperlipidemia, Diabetes Mellitus
- Trial name
- NCT01606930
- Testing
- Patient Primer Tool
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Walter Reed National Military Medical Center
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