Clinical trials: Vascular Disease，Peripheral
Peripheral Arterial Disease(PAD)
Effects of Virtual Reality Exercises on Individuals With Peripheral Artery Disease
The aim of this study is to investigate the effects of virtual reality exercises on lower extremity skin temperature, arterial stiffness, gait parameters and enjoyment of exercise in individuals with peripheral arterial disease.
- Trial name
- NCT06618131
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Dokuz Eylul University
Atherosclerotic Cardiovascular Disease
In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease
Study CKJX839B1FR01 in an In silico trial to predict the efficacy of Inclisiran therapy on major adverse cardiovascular events (MACE) and cardiovascular (CV) death in virtual patients with atherosclerotic cardiovascular disease…
- Trial name
- SIRIUS (NCT05974345)
- Testing
- Inclisiran sodium, Ezetimibe, Evolocumab
- Where
- France
- Volunteers
- 204,691 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus, Diabetic Foot
Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia
Diabetic foot syndrome (DFS) is a disease caused by neurogenic (concerning the nervous system), vascular, mechanic and metabolic factors, which are further complicated by an impairment of the immune system and a corresponding…
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Foot, Critical Limb Ischemia
- Trial name
- August-1 (NCT01599442)
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- GWT-TUD GmbH
Patient With IV Cannula Induce Phlebitis
Comparison of Magnesium Sulphate Versus Cold Compress in IV Cannula Induces Phlebitis
The use of intravenous (IV) devices is an integral part of patient care in hospitals, clinics, maternity home etc. approximately 80% of hospitalized patients receive I.V therapies.
- Trial name
- NCT06072729
- Testing
- comparison of magnesium sulphate versus cold compression
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Peripheral Arterial Disease
Long-term Pleiotropic Effect of Statins in Patients With Peripheral Arterial Disease
The purpose of this study is to determine the long-term effects of statins, atorvastatin, upon Nitric Oxide, as an endothelial function assessment, and C-Reactive Protein, an inflammatory marker, levels in patients with…
- Trial name
- NCT01041729
- Testing
- Atorvastatin, Standard Medical Treatment
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Getafe
Peripheral Vascular Disease
Effects of Paclitaxel on Intimal Hyperplasia
This is a single, one time, limited dose infusion of Paclitaxel, that will potentially prevent recurrent stenosis secondary to intimal hyperplasia when compared to the control group at 10 months.
- Trial name
- Pac1 (NCT01454778)
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Patrick Kelly
Raynaud's Phenomenon
Efficacy of ORM-12741 for Prevention of Raynaud's Phenomenon
Raynaud's phenomenon (RP) is a disorder of the digital blood vessels resulting in episodic impairment of blood flow. During an attack of RP which commonly affects the hands and feet these arteries contract briefly which limits…
- Trial name
- REINO (NCT01315899)
- Testing
- ORM-12471 30mg, ORM-12471
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Orion Corporation, Orion Pharma
Multiple Myeloma, Peripheral Neuropathy
Skin Biopsies in Chemotherapy-Induced Neuropathy
Neuropathy is a common side effect of chemotherapeutics used for the treatment of multiple myeloma, including vincristine, thalidomide and bortezomib. The neuropathy induced by these drugs is often preferentially small fiber.
- Trial name
- NCT00956033
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Erasmus Medical Center
Restenosis, Peripheral Arterial Disease
Local Delivery of Paclitaxel Via the TAPAS Catheter to Prevent Restenosis From Percutaneous Femoropopliteal Intervention
The purpose of this study is to assess the safety and efficacy of administering intra-arterial paclitaxel in the femoropopliteal arteries via the TAPAS catheter following percutaneous revascularization to prevent restenosis.
- Trial name
- PacTAP (NCT01599078)
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Midwest Cardiovascular Research Foundation
Peripheral Artery Disease
Walking Impairment Questionnaire in PAD
Purpose is to test and validate a new questionnaire (the WELCH questionnaire) to estimate walking capacity in patients with claudication
- Trial name
- WELCH (NCT01114178)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 340 people
- Sponsor
- University Hospital, Angers
Cardiovascular Diseases, Peripheral Vascular Diseases
Epidemiology of Venous Disease
To conduct several studies on the epidemiology of venous disease.
- Conditions
- Cardiovascular Diseases, Peripheral Vascular Diseases, Telangiectasis
- Trial name
- NCT00005392
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Intermittent Claudication, Arteriosclerosis
EW-A-401 to Treat Intermittent Claudication
This study will test the safety of a drug called EW-A-401 in patients with intermittent claudication - pain and discomfort in the legs due to blockages of the arteries.
- Trial name
- NCT00080392
- Testing
- DNA Plasmid Vector, EW-A-401 DNA Plasmid Vector
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Ischaemic Stroke
Combined tDCS+PNS After Acute Stroke
Recent work showed that application of peripheral nerve and cortical stimulation independently can induce 10-15 % improvement in motor performance in patients with chronic stroke.
- Trial name
- NCT01207336
- Testing
- combined transcranial direct current stimulation and electrical peripheral nerve stimulation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Peripheral Arterial Disease, Peripheral Vascular Disease
BOLT Lithotripsy RESTORE BTK Trial
The RESTORE (BTK) below the knee study is a prospective, non- randomized, multi-center study for treatment of stenotic lesions with the Bolt Intravascular Lithotripsy System.
- Trial name
- NCT05535907
- Testing
- Intravascular Lithotripsy
- Where
- 4 sites in Austria, Croatia and 2 more
- Volunteers
- 20 people
- Sponsor
- Bolt Medical
Sarcoma, Soft Tissue, Soft Tissue Sarcoma
Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
The purpose of this research study is to look at whether giving a drug called dexrazoxane with standard of care doxorubicin affects the progression of the disease.
- Conditions
- Sarcoma, Soft Tissue, Soft Tissue Sarcoma, Undifferentiated Pleomorphic Sarcoma, Leiomyosarcoma
- Trial name
- NCT02584309
- Testing
- Dexrazoxane, Doxorubicin
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Washington University School of Medicine
Peripheral Vascular Diseases
Post-Market Registry of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis Implanted in Peripheral Vessels
The primary objective of the VBX 17-04 registry is to collect post-market safety and performance data of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (VBX Stent Graft) in peripheral vessels in patients who require…
- Trial name
- EXPAND (NCT03720704)
- Testing
- GORE VIABAHN VBX Balloon Expandable Endoprosthesis
- Where
- 11 sites in France, Germany and 3 more
- Volunteers
- 280 people
- Sponsor
- W.L.Gore & Associates
Multiple Myeloma and Malignant Lymphoma
A Study of KRN125 in Patients With Multiple Myeloma and Malignant Lymphoma
To determine if KRN125 is non-inferior to filgrastim for the mobilization of hematopoietic stem cells into the peripheral blood in patients with multiple myeloma.
- Trial name
- NCT05007652
- Testing
- KRN125(pegfilgrastim), PLR001(plerixafor), KRN8601(filgrastim), PLR001(plerixafor)
- Where
- 21 sites in Japan
- Volunteers
- 64 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Peripheral Artery Disease, Intermittent Claudication
Home-based Circuit Training for People With Intermittent Claudication
The purpose of the study is to assess the feasibility of undertaking a randomised controlled trial investigating the effectiveness of a 12-week home-based exercise programme for people with intermittent claudication.
- Trial name
- WALKSTRONG (NCT05059899)
- Testing
- Exercise group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Coventry University
Peripheral Vascular Disease
Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease
This is the first clinical research trial in which intravenous Prostaglandin E1 (PGE1 is a vasoactive hormone) will be used as supportive treatment along with the angioplasty procedure to treat or open up a blocked artery within…
- Trial name
- NCT00053716
- Testing
- Liprostin [liposomal Prostaglandin E1]
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Endovasc
Cancer, Thrombus
The Impact of Climate Environment in Different Latitudes on the Occurrence of PICC Complications
In this study, eligible subjects were randomly assigned to the experimental or control group through randomization (1:1). Under the guidance of electrocardiographic Doppler ultrasound guided puncture and catheterization (EDUG)…
- Conditions
- Cancer, Thrombus, Phlebitis, Infections
- Trial name
- PICC (NCT05870449)
- Testing
- tunneled PICC, routine PICC
- Volunteers
- 1,666 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
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