Clinical trials: Vascular Disease Detected
Diabetes Mellitus, Diabetic Retinopathy
Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Funduscopic Images
AEYE-DS is a software device developed to increase compliance with diabetic retinopathy screening by automatically detecting more-than-mild diabetic retinopathy from digital funduscopic images using AI-based software.
- Trial name
- NCT05857943
- Testing
- AEYE-DS Software
- Where
- 3 sites in United States
- Volunteers
- 363 people
- Sponsor
- AEYE Health Inc
Coronary Artery Disease
Perfusion Imaging and CT -Understanding Relative Efficacy
To determine the relative efficacy of Cardiac Computed Tomography Angiography (CCTA) and Single Positron Emission Computed Tomography (SPECT) in patients with an intermediate risk of CAD.
- Trial name
- PICTURE (NCT00486447)
- Testing
- 64 Channel VCT
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- GE Healthcare
Acute Coronary Syndromes
Investigation of the Biomarker Copeptin in Patients With Acute Myocardial Infarction
While troponin is not detectable until several hours after an Acute Myocardial Infarction (AMI), copeptin is expected to be elevated very early after an AMI.
- Trial name
- CHOPIN (NCT00952744)
- Where
- 11 sites in United States
- Volunteers
- 2,071 people
- Sponsor
- Brahms AG
Pulmonary Embolism
External Validation of a Deep Learning Based Model for Pulmonary Embolism Detection on Chest CT Scans
The scope of this study is the external validation of an explainable deep learning-based classifier for the diagnosis and detection of pulmonary embolism in computed tomography pulmonary angiography (CTPA) and contrast enhanced…
- Trial name
- NCT05333042
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- OncoRadiomics
Amputation Wound, Peripheral Arterial Disease
Wound Imaging Study to Gather Clinical References for a Device to Assist Selecting Level-of-amputation in PAD Patients
This is a proof-of-concept study to collect images to train a CADe algorithm to predict the correct level of amputation in individuals scheduled for amputation secondary to PAD.
- Trial name
- WISCR (NCT03611361)
- Testing
- SpectralMD DeepView Wound Imaging System 2.0
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- SpectralMD
Coronary Artery Disease
Detection of Coronary Artery Disease With Micro Electro-Mechanical Sensors
This study aims to validate the sensor data of gyroscope and accelerometer in detection of hemodynamically significant CAD.
- Trial name
- DECADE (NCT04290091)
- Where
- Finland
- Volunteers
- 930 people
- Sponsor
- Precordior Ltd
Coronary Heart Disease
Study to Detect Biomarker Gradients in Coronary Arteries Using the Liquid Biopsy System
The Liquid Biopsy System (LBS) is a new catheter (thin tube) designed for sampling blood directly from coronary arteries. These arteries supply blood to muscles of the heart and can become blocked by 'plaques' leading to chest…
- Trial name
- CS1 (NCT02119767)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- PlaqueTec Ltd
Acute Coronary Syndrome
The Use of the Master Caution System (MCS) for Continuous Monitoring and Detection of Dysrhythmias and Ischemic Events
The purpose of this study is to evaluate the effectiveness and usability of the Master Caution System for 12 leads continuous monitoring of ECG signal in the ICCU.
- Trial name
- NCT03001206
- Testing
- Master Caution System
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- HealthWatch Ltd.
Coronary Artery Disease
Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases
This is a multi-center, prospective, non-randomized, double-blinded trial to evaluate the sensitivity and specificity of the CADence device in detecting the existence of clinically significant coronary artery disease as…
- Trial name
- TURBULENCE (NCT01743040)
- Testing
- CADence
- Where
- 24 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- AUM Cardiovascular, Inc.
Diabetic Retinopathy, Diabetic Eye Problems
Detection and Classification of Diabetic Retinopathy From Posterior Pole Images With A Deep Learning Model
The duration of diabetes is directly related to eye complications. Diabetic retinopathy affects 80 percent of those who have had diabetes for 20 years or more.
- Conditions
- Diabetic Retinopathy, Diabetic Eye Problems, Diabetic Macular Edema
- Trial name
- NCT04805541
- Testing
- Color Fundus Photography, Mydriatic Agent, EyeCheckup - AI Based DR Screening
- Where
- Turkey (Türkiye)
- Volunteers
- 900 people
- Sponsor
- Ural Telekomunikasyon Sanayi Ticaret Anonim Sirketi
Intracerebral Hemorrhage
ADVANCE- Automated Detection and Volumetric Assessment of ICH
To evaluate the performance of the Viz ICH VOLUME algorithm.
- Trial name
- NCT04733638
- Testing
- Viz ICH VOLUME
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Viz.ai, Inc.
Diabetic Retinopathy, Diabetes
OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection
In the United States, only 62% of the 37 million people with diabetes receive annual screening exams for diabetic retinopathy. One of the goals of the US Department of Health and Human Services Healthy People 2030 campaign is to…
- Trial name
- NCT06343350
- Testing
- OPTDR01 software application
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Optain Health
Stroke, Ischemic
SYNCHRONISE: LVO Triage Timing and Outcome Study
The objective of this study is to evaluate the impact of Viz LVO in hospital systems with non-interventional and interventional (spoke and hub) stroke centers on the timing and outcomes of patients with suspected acute ischemic…
- Trial name
- NCT04608617
- Testing
- Viz LVO (De Novo Number DEN170073), Baseline Effectiveness Cohort
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Viz.ai, Inc.
Atrial Fibrillation, Hypertension
Validation Study of an Advanced Blood Pressure Monitor
The proposed clinical study aims to validate the effectiveness of the WPM04 blood pressure monitor developed by Withings as a diagnostic tool for cardiovascular disorders.
- Conditions
- Atrial Fibrillation, Hypertension, Valvular Heart Disease
- Trial name
- TALISMAN (NCT04030494)
- Testing
- BP measurement, AF detection, VHD detection
- Where
- France
- Volunteers
- 218 people
- Sponsor
- Withings
Anterior Ischemic Optic Neuropathy, Ischemic Optic Neuropathy
Epidemiology Study of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The objectives of this study were to: (1) evaluate the natural history of non-arteritic anterior ischemic optic neuropathy (NAION); (2) estimate the population incidence of NAION; and (3) identify potential risk factors for NAION.
- Trial name
- NCT01260324
- Testing
- No intervention given in this observational study
- Volunteers
- 21,283 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Peripheral Vascular Disease
Impedance Sensor Evaluated in Peripheral Artery Disease for Tissue Detection
The objective of the study is to evaluate the feasibility of the CSGS sensor to differentiate tissues involved in Peripheral Artery Disease (PAD).
- Trial name
- SEPARATE (NCT06112054)
- Testing
- Clotild Smart Guidewire System (CSGS)
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Sensome
Vasospasm
Comparing the Nautilus NeuroWaveTM to TCD or DSA for the Detection of Vasospasm
To determine the efficacy of using the Jan Medical NNW system as a diagnostic aid in detection of moderate and severe vasospasm for detection of vasospasm in patients with subarachnoid hemorrhage.
- Trial name
- NCT02071875
- Testing
- Nautilus NeuroWaveTM recording
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Jan Medical, Inc.
Hypertension, Pulmonary, Heart Failure With Reduced Ejection Fraction
Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
This is a prospective, observational study evaluating whether heart sounds (phonocardiograms) and three-lead electrocardiograms (ECGs) recorded using the Eko CORE 500 digital stethoscope can help detect pulmonary hypertension…
- Trial name
- PH ELEFT 2-0 (NCT07087613)
- Testing
- Eko CORE 500 Digital Stethoscope
- Where
- 4 sites in United States
- Volunteers
- 3,850 people
- Sponsor
- Eko Devices, Inc.
Heart Disease, Ischemic Heart Disease
A Study to Examine MPI SPECT Imaging With BMS068645 and Adenosine Compared to Coronary Angiography
The purpose of the study is to determine whether BMS068645 is as effective as Adenosine SPECT at detecting blockages in heart arteries, and to determine if it will have fewer side effects
- Trial name
- NCT00162084
- Testing
- apadenoson
- Where
- 77 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Forest Laboratories
Coronary Artery Disease
Non-invasive Point-of-care Diagnosis Using Machine Learning and Signal Analytics to Transform Early Detection of Heart Disease
This study is designed as a repository study to collect resting cardiac phase signals and subject meta data from eligible subjects using the Phase Signal Recorder (PSR) prior to coronary angiography.
- Trial name
- IDENTIFY (NCT03864081)
- Testing
- Phase Signal Recorder
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Analytics For Life