Clinical trials: Vascular Dissection
Type B Aortic Dissection
Korean Registry of Thoracic Endovascular Aortic Repair Timing for Type B Aortic Dissection (K-TEAM Study): A Prospective Multicenter Registry
Prospective, single-arm, multi-center registry study A total of 50 subjects with Type B aortic dissection who meet all inclusion and exclusion criteria will be included.
- Trial name
- NCT02816333
- Sponsor
- Yonsei University
Blood Loss, Intensive Care
D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy
Evaluating the differences between D2 and D3 lymphadenectomy in laparoscopic right hemicolectomy in patients with right cancer colon post-operative outcome, intra-operative blood transfusion, post-operative ICU admission…
- Conditions
- Blood Loss, Intensive Care, Anastomotic Leakage, Lymph Node Disease
- Trial name
- NCT06049758
- Testing
- LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (intervention), Enoxaparin 40 Mg/0.4 mL Injectable Solution, Levofloxacin 500mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Esophageal Lesion, Barrett Esophagus
Endoscopic Submucosal Dissection (ESD)
This registry is to evaluate the procedural and clinical outcomes in patients undergoing endoscopic submucosal dissection. All patients will receive standard of medical care and no experimental interventions will be performed.
- Conditions
- Esophageal Lesion, Barrett Esophagus, Gastrointestinal Lesions
- Trial name
- ESD (NCT05468008)
- Testing
- Endoscopic Submucosal Dissection
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- AdventHealth
Melanoma (Skin)
Interferon Alfa Following Surgery in Treating Patients With Stage III Melanoma
RATIONALE: Interferon alfa may interfere with the growth of the cancer cells. It is not yet known if this treatment is more effective than observation following surgery for stage III melanoma.
- Trial name
- NCT00006249
- Testing
- pegylated interferon alfa, adjuvant therapy
- Where
- 104 sites in Australia, Belgium and 16 more
- Volunteers
- 1,258 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Ulcers, Gastric
Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal Dissection
The purpose of this clinical trial is to find out the effectiveness of voronasan in combination with aluminum phosphate gel in the treatment of post-operative ESD ulcers.
- Trial name
- NCT06526455
- Testing
- Vonoprazan, Esomeprazole
- Where
- 4 sites in China
- Volunteers
- 196 people
- Sponsor
- Shicai Ye
Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia
Piecemeal Versus En Bloc Resection of Large Rectal Adenomas
Currently, colonoscopy is the safest way to detect bowel tumors and polyps, since these can be biopsied and removed in one working process.
- Conditions
- Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia, Colorectal Adenomatous Polyp, Colorectal Low Grade Intraepithelial Neoplasia
- Trial name
- PERLA (NCT02238938)
- Testing
- en-bloc resection, piecemeal resection
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 110 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Thyroid Cancer, Papillary
The Efficacy and Safety of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma
The aim of this study is to investigate the efficacy and safety of prophylactic central lymph node dissection in papillary thyroid carcinoma.
- Trial name
- NCT02418390
- Testing
- prophylactic central lymph node dissection
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Type A Aortic Dissection, Hypothermia
Arch-Clamping Technique Under Mild Hypothermia in Treating With Acute Type A Aortic Dissection
The study is a multicenter, three-arm, open-label, randomized, parallel-controlled trial, which plans to enroll 306 participants diagnosed with acute type A aortic dissection (ATAAD) from 7 hospitals in China.
- Conditions
- Acute Type A Aortic Dissection, Hypothermia, Total Aortic Arch Replacement, Frozen Elephant Trunk
- Trial name
- AHEAD (NCT07150559)
- Testing
- Arch-Clamping Technique under Mild Hypothermia, Arch-Clamping Technique under Moderate Hypothermia, Total Arch Replacement combined Frozen Elephant Trunk Implantation using Bilateral Antegrade Cerebral Perfusion under Moderate Hypothermic Circulatory Arrest
- Where
- China
- Volunteers
- 306 people
- Sponsor
- Beijing Anzhen Hospital
Early Gastric Cancer
Endoscopic Submucosal Dissection Versus Gastrectomy
Gastrectomy is curative treatment for early gastric cancer (EGC). Recently, endoscopic submucosal dissection (ESD) has been accepted as standard treatment in selected patients with negligible risk of lymph node metastasis.
- Trial name
- NCT02216110
- Testing
- Surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Soonchunhyang University Hospital
Colon Cancer
Investigate the Radical Extent of Lymphadenectomy of LAparoscopic Right Colectomy for Colon Cancer(RELARC).
To investigate whether extended lymphadenectomy (CME) in laparoscopic colectomy could improve disease-free survival in patients with right colon cancer, compared with standard D2 radical operation.
- Trial name
- RELARC (NCT02619942)
- Testing
- D2 radical operation, Complete mesocolic excision (CME)
- Where
- China
- Volunteers
- 1,072 people
- Sponsor
- Peking Union Medical College Hospital
Aortic Dissection
Nordic Consortium for Acute Type A Aortic Dissection-2
The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a multicenter research collaboration involving up to 19 units in the Nordic countries and one in The Netherlands.
- Trial name
- NORCAAD-2 (NCT06862583)
- Testing
- surgery, endovascular intervention
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
Meningocele, Meningomyelocele
Propellers Flaps for Meningomylocele Defects
To evaluate reliability of free style propeller perforator flap for coverage MMC soft tissue defect follow a well-established step that overcome the usual problem of pedicled perforators propellers flaps.
- Trial name
- NCT05188300
- Testing
- Freestyle pedicled perforators propellers flaps for meningomyelocele defects
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Superficial Esophageal Cancer
Human (Autologous) Oral Mucosal Cell Sheet Transplantation After ESD in Patients With Superficial Esophageal Cancer
The purpose of this study is to evaluate the efficacy and safety of esophageal epithelial regenerative treatment by the transplantation of the product, CLS2702C, to the esophageal wound site after extensive ESD for superficial…
- Trial name
- NCT02866019
- Testing
- CLS2702C/CLS2702D
- Where
- 3 sites in Japan
- Volunteers
- 10 people
- Sponsor
- CellSeed Inc.
Rectal Cancer
Comparison of Low and High Ligation With Apical Lymph Node Dissection in the Laparoscopy Rectal Cancer
The purpose of this study is to explore the different impacts of high and low ligation in laparoscopic rectal interior resection on postoperative anastomotic leakage and proximal bowel necrosis and stenosis, as well as the…
- Trial name
- PLAND (NCT03498885)
- Testing
- Low ligation, High ligation
- Where
- China
- Volunteers
- 466 people
- Sponsor
- WEIDONG LIU，MD
Recurrence, Metastasis
Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma)
This clinical trial is designed to evaluate the role of lymph node dissection in the prevention of recurrence and metastasis after radical nephroureterectomy for high-risk primary upper tract urothelial carcinoma (UTUC) patients.
- Conditions
- Recurrence, Metastasis, Upper Tract Urothelial Carcinoma, Lymph Node Dissection
- Trial name
- UTUC (NCT03230201)
- Testing
- Lymph node dissection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Gastrointestinal Polyps
Pathfinder Registry
This study collects information regarding your procedure. No changes will be done to your procedure and you are asked to consent for the use of your data in our database.
- Trial name
- NCT05141032
- Testing
- Endoscopic Submucosal Dissection with Pathfinder/Overtube device
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Baylor College of Medicine
RECTAL NEOPLASMS
Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas
Objective: Recent non-randomized studies suggest that extended endoscopic submucosal dissection (ESD) is equally effective in removing large rectal adenomas as transanal endoscopic microsurgery (TEM).
- Trial name
- TEMENDO (NCT01023984)
- Testing
- TEM - Transanal Endoscopic Microsurgery, ESD - Endoscopic Submucosal Dissection
- Where
- Italy
- Sponsor
- European Association for Endoscopic Surgery
Head and Neck Cancer
The Safety and Efficacy of the Harmonic Scalpel in Neck Dissection
Recently, the HS has been used in head and neck surgery as an alternative to conventional hand-tied ligation for hemostasis, which is a time-consuming procedure.
- Trial name
- NCT01488682
- Testing
- Neck dissection with Harmonic scalpel, neck dissection with conventional hand-tie ligation
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Yonsei University