Clinical trials: Vascular Malformations
Hereditary Haemorrhagic Telangiectasia
Evaluation of Video-assisted Instructions of Nasal Self-packing in Patients with HHT
Inserting nasal self-packings is a secure method leaving patients more self-confident. We provide a video on https://www.youtube.com/watch?v=LaioLYfSJ-E demonstrating how to use nasal self-packings.
- Trial name
- NCT03841422
- Testing
- video-assisted nasal self-packing
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital, Essen
AVM (Arteriovenous Malformation) Intracranial
Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment
Cerebrovascular malformations (CVMs) are a heterogeneous group of disorders and can be classified histopathologically into five main categories: arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVDs)…
- Trial name
- NCT05729295
- Testing
- Endovascular embolization or surgery
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer, Breast Abnormalities
Evaluate Breast Masses Using a New Method of Ultrasound Contrast to Detect Abnormal Blood Flow in Breasts
The purpose of this study is to determine if breast imaging with ultrasound can be improved by using 1) a ultrasound attachment with two transducers and 2) a contrast agent.
- Trial name
- NCT00722683
- Testing
- Ultrasound Imaging with Contrast
- Where
- United States
- Sponsor
- University of Michigan
Hemodialysis Complication, Dialysis; Complications
Handheld Ultrasound-guided Cannulation of Difficult Haemodialysis Arteriovenous Access by Renal Nurses
Cannulation of complex arteriovenous fistula (AVF) or graft (AVG) is a challenge to renal nurses. Ultrasound (US) guidance on central and peripheral venous access visualisation has been widely adopted in nephrology and shown to…
- Conditions
- Hemodialysis Complication, Dialysis; Complications, Vascular Access Site Haematoma, Vascular Access Complication
- Trial name
- NCT05410691
- Testing
- Handheld US device
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National Healthcare Group, Singapore
Stenosis, Restenosis
Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft
The objective of this study is to assess the safety and effectiveness of the COVERA™ Vascular Covered Stent for the treatment of stenotic lesions in the upper extremity venous outflow of the Arteriovenous (AV) access circuit.
- Trial name
- AVeNEW (NCT02649946)
- Testing
- Covera Vascular Covered Stent following PTA, Percutaneous Transluminal Angioplasty (PTA) with Uncoated PTA Balloon
- Where
- 24 sites in United States, Australia and 6 more
- Volunteers
- 280 people
- Sponsor
- C. R. Bard
May-Thurner Syndrome
The Use and Reproducibility of Duplex Ultrasound to Provide Indices of Left Common Iliac Vein Diameter
The goal of this feasibility/pilot study is to investigate whether or not vascular ultrasound can be used to aid the diagnosis of May Thurner Syndrome, in adult patients presenting to the vascular department with unexplained left…
- Trial name
- NCT06180122
- Testing
- Duplex ultrasound
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Chronic Kidney Disease
A Study of PRT-201 Administered Immediately After Arteriovenous Fistula Creation in Patients With Chronic Kidney Disease
The purpose of this study is to determine if PRT-201 when applied to a limited segment of your blood vessel (about 2 inches) immediately after surgery to create an arteriovenous fistula is safe and improves the patency of your…
- Trial name
- NCT01305824
- Testing
- PRT-201
- Where
- 23 sites in United States
- Volunteers
- 151 people
- Sponsor
- Proteon Therapeutics
Arteriovenous Fistula, Fistula
Cutting Balloon Versus Non-cutting Balloon for the Treatment of Venous Stenosis in the Fistulas of Hemodialyzed Patients
The main objective of this study is to evaluate and compare the primary patency rate at 12 months in a group of hemodialysis patients operated on by cutting balloon and in a group of hemodialysis patients operated by conventional…
- Trial name
- PREST (NCT01321866)
- Testing
- Cutting balloon angioplasty, Angioplasty
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
End Stage Renal Disease on Dialysis
Comparing Surgical and Endovascular Arteriovenous Fistula Creation
Patients with end-stage kidney disease (ESKD) who use hemodialysis to filter their blood require vascular access for the dialysis machine; the most common type of vascular access is called an arteriovenous fistula (AVF).
- Trial name
- NCT05654103
- Testing
- endoAVF, surgAVF
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Venous Malformation, Pain
A Study of Enalapril in Treatment of Venous Malformations
The goal of this clinical trial is to explore if enalapril can be used to treat painful venous malformations. The main question it aims to answer are: Can enalapril reduce pain and volume of the malformation and increase quality…
- Conditions
- Venous Malformation, Pain, Quality of Life, Vascular Malformation
- Trial name
- EVA (NCT06788314)
- Testing
- Enalapril
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
End Stage Renal Disease, Arteriovenous Fistula
Effect of Pre-operative Forearm Exercises on Arterial Venous Fistula Maturation and Blood Flow
This study will investigate the effect of pre-operative exercise on hemodynamics in the fistula artery and vein, Pre and Post Arteriovenous Fistula Formation as well as the suitability of Cannulation of Arteriovenous Fistula at…
- Trial name
- NCT03886116
- Testing
- Exercise
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore General Hospital
Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis
Sutureless Closure for Primary Total Anomalous Pulmonary Venous Connection
The purpose of this study is to assess the percentage of pulmonary venous stenosis after TAPVC repair with sutureless closure.
- Conditions
- Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis, Sutureless Closure
- Trial name
- TAPVC (NCT04938921)
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Children's Hospital 1
Telangiectasia, Hereditary Hemorrhagic, Osler Rendu Disease
Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)
Timolol is a nonselective β-blocker commonly used in the treatment of glaucoma. Recently it has been used topically for the treatment of superficial hemangiomas.
- Trial name
- TEMPO (NCT02484716)
- Testing
- Timolol nasal spray
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Hospices Civils de Lyon
Arteriovenous Fistula Pain
Arteriovenous Fistula Pain and Cold Application
TThis study was designed as a single-group comparative prospective intervention study. The aim of the study was to assess the effectiveness of different pain management interventions during AVF cannulation.
- Trial name
- NCT06862687
- Testing
- Cooling Spray, Cold Aloe Vera Gel Application, Standard Procedure (Control Condition)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Rendu Osler Disease, Telangiectasia, Hereditary Hemorrhagic
BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT).
The recognized manifestations of HHT are all due to abnormalities of vascular structure. Epistaxis and digestive arteriovenous malformations may be responsible for severe hemorrhages in 5% of HHT patients, requiring repeated…
- Trial name
- BABH (NCT03227263)
- Testing
- Bevacizumab, sodium chloride 0.9%
- Where
- 4 sites in France
- Volunteers
- 24 people
- Sponsor
- Hospices Civils de Lyon
AV Fistula
av Fistula Patency Loss as a Cause of Fistula Failure and Hyperphosphatemia
Assessment of arteriovenous fistula patency loss which leads to av fistula failure and its relation to high serum phosphate level in chronic hemodialysis patients.
- Trial name
- NCT05569109
- Testing
- doppler ultrasound
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cerebrovascular Diseases, Ischemic Stroke
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
This study encompasses the maintenance and utilization of a repository of samples from patients with cerebrovascular disease and stroke.
- Conditions
- Cerebrovascular Diseases, Ischemic Stroke, Repository
- Trial name
- NCT02910180
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Cedars-Sinai Medical Center
Aneurysms, Arteriovenous Malformations
Tetracycline-Derivatives for Treatment of Cerebral Arteriovenous Malformations and Aneurysms
The purpose of this pilot study is to investigate the use of minocycline and doxycycline as medical therapy for inoperable or partially treated arteriovenous malformations (AVMs) and giant aneurysms.
- Trial name
- NCT00243893
- Testing
- minocycline, doxycycline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Francisco
Arteriovenous Fistula, Cannulation
Coronal Mode Ultrasound Guided Hemodialysis Cannulation: Comparison With Standard Cannulation Technique
Infiltrations from cannulation difficulties result in significant morbidity including loss of vascular access (VA) loss in hemodialysis (HD). Cannulation is reliant on personnel skill and VA characteristics.
- Trial name
- NCT02814721
- Testing
- Sonic Window ultrasound device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Henry Ford Health System
Coronary Artery Disease, Myocarditis
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
This study aims to identify and assess new CMR techniques that can improve current CMR protocols.
- Conditions
- Coronary Artery Disease, Myocarditis, Infiltrative Cardiomyopathy, Dilated Cardiomyopathy
- Trial name
- NCT04464655
- Where
- Canada
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre