Clinical trials: Vascular Occlusive Disease
Peripheral Arterial Disease, Femoropopliteal Stenosis
PMCF Study for Peripheral Arteries Above the Knee (ATK)
The rationale of this study is to confirm and support the clinical safety and performance of the products in a real-word population of 350 patients who underwent an endovascular intervention within standard-of-care (SOC) of the…
- Conditions
- Peripheral Arterial Disease, Femoropopliteal Stenosis, Angiopathy, Peripheral
- Trial name
- NCT05312580
- Where
- 9 sites in Austria, France and 1 more
- Volunteers
- 387 people
- Sponsor
- Cordis US Corp.
Dialysis Patients
Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients
The main objective is to evaluate in hemodialysis patients the effects of two intradialytic rehabilitation programs based on physical exercise, with or without the application of blood flow restriction, on myocardial stunning and…
- Trial name
- ERO-CARD (NCT07269379)
- Testing
- Chronic phase - HDEX/HDBFRE, Acute phase - HDEX/HDBFRE
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
Peripheral Artery Disease (PAD), CT Perfusion
Clinical Value of CT Perfusion in Peripheral Artery Disease
Peripheral artery disease (PAD) affects millions worldwide and can lead to serious complications such as leg ulcers, gangrene, and amputation.
- Conditions
- Peripheral Artery Disease (PAD), CT Perfusion, Revascularization, Microcirculation
- Trial name
- iPAD (NCT07816757)
- Volunteers
- 200 people
- Sponsor
- Fudan University
Coronary Artery Disease
Randomized MicroPort's Firehawk DES Versus Xience V: TARGET I Trial
The purpose of this study is to evaluate new generation drug eluting stent (DES) of MicroPort of its safety, efficacy and delivery system in treating CAD.
- Trial name
- NCT01196819
- Testing
- Firehawk, Xience V
- Where
- China
- Volunteers
- 458 people
- Sponsor
- Shanghai MicroPort Medical (Group) Co., Ltd.
Delirium in Old Age, Delirium
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery…
- Conditions
- Delirium in Old Age, Delirium, Coronary Artery Disease
- Trial name
- PANDORA (NCT04093219)
- Testing
- IV acetaminophen
- Where
- 10 sites in United States
- Volunteers
- 901 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Severe Stenosis or Occlusion of Anterior Intracranial Circulation Vessels
The primary purpose of this study is to examine whether remote ischemic treatment can better the 90 - day neurological outcomes in acute ischemic stroke patients having severe stenosis or occlusion of anterior intracranial…
- Trial name
- RICASO (NCT06823128)
- Testing
- RIC, Guideline-based therapy
- Where
- China
- Volunteers
- 458 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Coronary Artery Disease, Diabetes Mellitus, Type 2
Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary Intervention
This will be a single-center, randomized, open-label, active-controlled, parallel-group study to investigate the platelet inhibition of Ticagrelor versus Clopidogrel with acetylsalicylic acid (ASA) as background therapy in…
- Trial name
- PLATIDE-PCI (NCT02748330)
- Testing
- Ticagrelor, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Valvular Disease, Valvular Heart Disease
Epidemiology and Long-term Outcome of Patients With VHD
Valvular heart diseases are significant problem in Polish population. Coexistence of coronary artery disease in patients with VHD increases the risk of death and affects further therapeutic strategy.
- Conditions
- Valvular Disease, Valvular Heart Disease, Aortic Valve Stenosis, Mitral Insufficiency and Aortic Stenosis
- Trial name
- BIA-WAD (NCT04527367)
- Testing
- Innovative medical technologies in invasive cardiology and cardiac surgery
- Where
- Poland
- Volunteers
- 2,500 people
- Sponsor
- Medical University of Bialystok
Coronary Artery Disease Obliterative, Chronic Total Occlusion (CTO)
A Prospective, Non-Randomized Pivotal Clinical Investigation to Demonstrate the Safety and Performance of the TrueCross Single-Use Microcatheter
The trial is a pivotal clinical investigation, which is a prospective, non-randomized pivotal clinical investigation to demonstrate the safety and performance of the TrueCross Single-use Microcatheter.
- Trial name
- NCT06030271
- Testing
- Microcatheter
- Where
- 7 sites in Georgia, Greece and 1 more
- Volunteers
- 60 people
- Sponsor
- Insight Lifetech Co., Ltd.
Stroke, Ischemic
EEG Patterns in Patients With Acute Ischemic Stroke Resulted From Large Vessels Occlusion in the Anterior Circulation
Clinical deterioration is observing in up to forty percent of patients with acute ischemic stroke (AIS) due to large vessels occlusion.
- Trial name
- NCT04412434
- Testing
- Electroencephalography (EEG)
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- rambam62
Acute Ischemic Stroke, Posterior Circulation Brain Infarction
Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score
Posterior circulation strokes (PCS) represent ~30% of all ischemic strokes, but existing prognostic tools are limited, especially for non-basilar artery occlusions.
- Conditions
- Acute Ischemic Stroke, Posterior Circulation Brain Infarction, Arterial Occlusion Disease
- Trial name
- PC-CBS (NCT07122934)
- Testing
- Assessment of cervico-cerebral arterial occlusion pattern
- Volunteers
- 1,828 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Ischemic Stroke, Atherosclerosis
Preventive Effects of Ginseng Against Atherosclerosis
This study is a 12-month, double-blind, randomized, placebo-controlled trial. The purpose of this study is to determine whether ginseng is effective in the prevention of atherosclerosis and subsequent ischemic stroke.
- Trial name
- PEGASUS (NCT02796664)
- Testing
- Ginseng
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Dae Chul Suh
Dyslipidemia
A Study of LY2484595 in Patients With High LDL-C or Low HDL-C
The primary purpose of your participation in this study is to help answer the following research question(s) Whether LY2484595 in combination with a statin drug (atorvastatin, simvastatin or rosuvastatin; currently used to treat…
- Trial name
- NCT01105975
- Testing
- LY2484595, Atorvastatin, Simvastatin
- Where
- 59 sites in United States, Denmark and 4 more
- Volunteers
- 398 people
- Sponsor
- Eli Lilly and Company
Cardiovascular Diseases, Heart Diseases
Atherosclerosis and Omega-3 Fatty Acids in Alaskan Natives
To determine whether there were differences in the prevalence and extent of atherosclerotic lesions in the coronaries and aortas between Alaskan natives and non-natives, and whether the extent of the lesions was related to…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Arteriosclerosis
- Trial name
- NCT00005236
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Bypass
Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation
The aim of this study is to assess the effect of minimal (MECC) versus conventional (CECC) extracorporeal circulation on neurocognitive function after elective coronary bypass grafting (CABG) as well as whether this can be…
- Trial name
- NCT01213511
- Testing
- Coronary artery bypass grafting with the use of minimal extracorporeal circulation, Coronary artery bypass grafting under conventional extracorporeal circulation
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- AHEPA University Hospital
Atherosclerosis
Longitudinal Study in Perimenopausal Women With Risk Factors for Atherosclerosis
The study hypothesis (or theory) is that monthly loss of iron before menopause may reduce women's risk of hardening of the arteries, or atherosclerosis.
- Trial name
- NCT00921011
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Ohio State University
Coronary Artery Disease
Cobra II Study: Use of the Cobra™ Cobalt Super Alloy Coronary Stent System in the Treatment of Coronary Artery Disease
To demonstrate the safety and efficacy of the Cobra Cobalt Super Alloy Balloon-Expandable Coronary Stent System for the treatment of de novo and restenotic (previously unstented) lesions in native coronary arteries in subjects…
- Trial name
- NCT00744107
- Testing
- PCI with the Cobra™ Cobalt Super Alloy Coronary Stent System
- Where
- 7 sites in Germany, Israel and 2 more
- Volunteers
- 258 people
- Sponsor
- Medlogics Device Corporation
Coronary Artery Disease
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions in Small Vessels
The purpose of this study is to evaluate the safety and effectiveness of the PROMUS Element™ Everolimus-Eluting Coronary Stent System for the treatment of patients with up to 2 de novo atherosclerotic coronary artery lesions.
- Trial name
- PLATINUM SV (NCT01498692)
- Testing
- PROMUS Element Coronary Stent System
- Where
- 23 sites in United States, Australia and 4 more
- Volunteers
- 94 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease(CAD), de Novo Coronary Lesions
The Safety and Efficacy of New-Generation BRS vs. DCB for De Novo Large Coronary Artery Lesions: A Prospective RCT
This study plans to enroll 150 patients who are candidates for "intervention without implantation" therapy and they will be randomly assigned in a 1:1 ratio to either the new-generation Firesorb scaffold group (BRS group, N=75)…
- Trial name
- NCT07162792
- Testing
- bioresorbable scaffold, drug-coated balloon
- Volunteers
- 150 people
- Sponsor
- Xuzhou Third People's Hospital
Arterial Occlusive Diseases, Atherosclerosis
A Real World Evaluation of the ELUVIA Stent in Subjects With Lesions Located in the Femoropopliteal Arteries
The REGAL study is a European, prospective, multi-center Post-Market Clinical Follow-up (PMCF) trial providing additional data including health economics data to support the use of the ELUVIA stent in the treatment of lesions…
- Conditions
- Arterial Occlusive Diseases, Atherosclerosis, Vascular Diseases, Arteriosclerosis
- Trial name
- REGAL (NCT03037411)
- Testing
- Peripheral stenting
- Where
- 23 sites in Austria, Belgium and 3 more
- Volunteers
- 291 people
- Sponsor
- Boston Scientific Corporation
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