Clinical trials: Vascular Occlusive Disease
Coronary Arteriosclerosis
68Ga-DOTATATE PET-CTA Imaging for the Early Detection of Progressing Coronary Atherosclerosis
68Ga-DOTATATE is a PET radiotracer with high affinity and selectivity for somatostatin receptor 2 (SSTR 2) and is approved clinically for the evaluation of patients with neuroendocrine tumors.
- Trial name
- iPROGRESS (NCT04043377)
- Testing
- injection of 68Ga-DOTATATE
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dementia
Research on the Early and Prognosis Diagnosis of Vascular Dementia
Around 10% of stroke survivors develop dementia within 3 months after stroke and over 20% more stroke patients have dementia in the subsequent 3 years.
- Trial name
- NCT03152630
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Peripheral Artery Disease
BEETroot Juice to Reverse Functional Impairment in PAD
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-minute walk distance at four month follow-up in people with lower…
- Trial name
- BEET PAD (NCT05624125)
- Testing
- Beetroot juice
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Coronary Artery Disease
Determinants of Cardiac Risk Factor Modification in Latinos With Coronary Artery Disease
This is an observational study among Latino patients who have coronary artery disease. The goal of the study is to determine the association between having depressive symptoms and the ability to modify one's health behavior.
- Trial name
- NCT00248859
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Disease
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
This purpose of this trial is to demonstrate 30 day safety and effectiveness outcomes of the KARDION CORY P4 System in subjects who require hemodynamic support during a high-risk PCI procedure.
- Trial name
- NCT06445608
- Testing
- Percutaneous Mechanical Circulatory Support
- Where
- 18 sites in United States
- Volunteers
- 310 people
- Sponsor
- Kardion Inc
Atherosclerotic Cardiovascular Disease (ASCVD), Secondary Prevention
Aspirin 50 mg vs. 100 mg in Elderly Cardiovascular Disease Patients
Elderly patients with cardiovascular disease face a high risk of both thrombotic and bleeding events when receiving antithrombotic therapy.
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Secondary Prevention, Cardiovascular Diseases
- Trial name
- LAPIS (NCT07542860)
- Where
- China
- Volunteers
- 5,448 people
- Sponsor
- Peking University First Hospital
Coronary Artery Disease, Cardiovascular Diseases
Functional Diagnostic Accuracy of Quantitative Flow Ratio in Tandem Lesions and Virtual Stenting
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. Virtual stent implantation technique combined with QFR was recently developed to predict the functional significance…
- Conditions
- Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia, Arterial Occlusive Diseases
- Trial name
- FORTRESS (NCT03405506)
- Testing
- Quantitative Flow Ratio (QFR)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Coronary Artery Disease
Optimization of Percutaenous Coronary Intervention With Liberal Use of Post-dilatation
To achieve optimal long-term clinical results after percutaneous coronary intervention (PCI), adequate deployment of stents is essential.
- Trial name
- OPTIMIZE-PCI (NCT06558474)
- Testing
- Liberal post-dilatation strategy during PCI
- Where
- Netherlands
- Volunteers
- 12,000 people
- Sponsor
- Cathreine BV
Coronary Disease, Heart Diseases
Myocardial Contrast Echocardiography (MCE) to Check for Living and Working Heart Muscle
Coronary artery disease (CAD) can cause poor blood flow and supply to the heart muscle. It can result in irreversible damage to the heart muscle and poor function.
- Trial name
- NCT00001891
- Testing
- Myocardial contrast echocardiography, Dobutamine echocardiography
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
A Single Center Study to Establish the Imaging Protocol of 99mTc-EC-DG in Evaluating the Presence and Severity of Coronary Artery Disease (CAD)
This study will assess the safety and tolerability of the investigational radiolabeled imaging agent technetium-99m-labeled ethylenedicysteine-deoxyglucose (99mTc-EC-DG).
- Trial name
- NCT01778218
- Testing
- Radiolabeled (99Tc) EC-DG (ethylenedicysteine-deoxyglucose
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cell>Point LLC
Coronary Artery Disease, Heart Disease
Biorepository: Indiana Health Study
Blood samples and health information (e.g., age at diagnosis, test results) are collected for the purposes of genetic research. The blood samples are assigned a number and stored in a repository for safe keeping until they are…
- Conditions
- Coronary Artery Disease, Heart Disease, Healthy
- Trial name
- IHS (NCT00741416)
- Where
- 14 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Fairbanks Institute
Type 2 Diabetes Mellitus
A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
The purposes of this study are: to investigate the extent of cardiovascular complications in a representative cohort (n=135) of adult patients with type 2 diabetes; to examine if modern non-invasive assessment can replace…
- Trial name
- NCT00133718
- Testing
- Combined lifestyle intervention and optimisation of pharmacological treatment
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Asker & Baerum Hospital
Coronary Artery Disease (CAD), Ischemic Heart Disease
ANGIOLITE PMCF Study ( rEPIC04F )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Angiolite sirolimus eluting stent to meet EU Medical Device regulation (MDR)…
- Trial name
- rEPIC04F (NCT05292014)
- Testing
- ANGIOLITE
- Where
- 6 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Fundación EPIC
Atherosclerosis of Arteries of the Extremities, Unspecified
Beneficial Effects of Grape Seed Proanthocyanidin Extrat on Progression of Atherosclerotic Plaques in Clinical Use
The purpose of this study is to investigate the antiatherogenic effect of GSPE in clinical use
- Trial name
- GSPE (NCT01707615)
- Testing
- GSPE, lifestyle intervention
- Volunteers
- 287 people
- Sponsor
- Jie Qiu
Coronary Artery Disease
Effects of Conditioning Exercises and Resistance Interval Training on Post CABG Patients.
Coronary artery disease (CAD) is a global health challenge influenced by diabetes, hypertension, and psychosocial stress, with women having a higher prevalence of Coronary microvascular disease.
- Trial name
- NCT06844591
- Testing
- Conditioning Exercises/ Aerobic Interval Training, Resistance Interval Training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Ischaemic Heart Disease
Outcomes of Drug Coated Balloon Angioplasty, A UK Real Life Experience From 2009 to 2015
This is a single center, retrospective, observational cohort study to assess the safety and efficacy of drug coated balloon (DCB) angioplasty in all forms of coronary artery disease.
- Trial name
- DCBNORWICH (NCT03603210)
- Testing
- Drug coated balloon angioplasty
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Coronary Artery Disease
Comparison Between Right and Left Radial Approach in Patients Undergoing Percutaneous Coronary Procedures
Our aim is to compare between right and left radial approach in patients undergoing percutaneous coronary procedures regarding feasibility and complications.
- Trial name
- NCT05626660
- Testing
- Coronary angiography and percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Atherosclerosis, Coronary, Coronary Stenosis
Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice
This study evaluates the effectiveness and safety rotational atherectomy in routine clinical practice.
- Trial name
- IRIS-ROTA (NCT03427996)
- Testing
- Rotational atherectomy
- Where
- 8 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
Safety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection
This study is aimed at examining the safety and efficacy of rotational atherectomy (RA) in nondilatable calcified lesion complicated by coronary dissection during percutaneous coronary intervention (PCI) procedure.
- Trial name
- NCT01701596
- Testing
- Immediate rotational atherectomy (RA), Delayed rotational atherectomy (RA)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Xijing Hospital
Retinal Vein Occlusion, Macular Edema
Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO)
This is a retrospective data collection study to evaluate the efficacy, safety, and re-injection interval of OZURDEX® in the treatment of macular edema due to RVO. Following informed consent, there were no patient study visits.
- Trial name
- NCT01411696
- Testing
- dexamethasone intravitreal implant 0.7 mg
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Allergan
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