Clinical trials: Vascular Patients
STEMI - ST-segment Elevation Myocardial Infarction
Effects of Nicorandil on Microvascular Dysfunction in Patients With STEMI Undergoing Primary PCI
Despite the success of restoration of epicardial blood flow by the primary percutaneous coronary intervention (PPCI), approximately one half of patients with ST-segment elevation myocardial infarction (STEMI) have failed…
- Trial name
- NORMAL (NCT06787430)
- Testing
- nicorandil
- Volunteers
- 170 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension (HTN)
Real Life Data From Hypertensive Patients Treated With Renal Denervation in Current Practice in France- French RENal Denervation Registry
Renal denervation (RDN) is a recent procedure that can be used to control BP (blood pressure) in hypertensive patients. Numerous publications from randomised trials have demonstrated the efficacy of RDN in this indication.
- Trial name
- FRIEND (NCT07206030)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Grenoble
Pulmonary Hypertension
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
This extended access study will assess the long-term safety and tolerability of bardoxolone methyl in qualified patients with pulmonary hypertension (PH) who previously participated in controlled clinical studies with bardoxolone…
- Trial name
- RANGER (NCT03068130)
- Testing
- Bardoxolone methyl
- Where
- 96 sites in United States, Argentina and 13 more
- Volunteers
- 261 people
- Sponsor
- Biogen
Aortic Diseases
Impact of Aortic Diseases on Quality of Life and Work Ability
Aortic diseases encompass a wide spectrum of congenital and acquired, acute and chronic conditions, characterized by high clinical and prognostic complexity.
- Trial name
- IMPACT-A (NCT07479186)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes, Hypertension
The Effects of Renin Angiotensin System Blockage (RAS), Calcium Channel Blocker and Combined Drugs on TWEAK, PTX3 and FMD Levels in Diabetic Proteinuric Patients With Hypertension
Diabetic nephropathy (DN) is the most important complication of diabetes mellitus (DM) and the most common cause of end-stage renal disease (ESRD).
- Conditions
- Diabetes, Hypertension, Proteinuria
- Trial name
- NCT00921570
- Testing
- Amlodipine, Valsartan
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Gulhane School of Medicine
Ischemic Stroke
Managing Aftercare for Stroke (MAS): MAS-I - a Cross Sectional Study of Post-rehabilitation Stroke Burden and Patients' Needs
In this first step of the study the investigators will assess the needs, disease burden and current treatments of long-term stroke patients (phase MAS-I).
- Trial name
- MAS-I (NCT02320994)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Charite University, Berlin, Germany
Peripheral Artery Disease
Evaluation of Patients With Suspected Endofibrosis
Define responses to exercise on both arterial bruits and oxymetry in patients referred for suspected endofibrosis.
- Trial name
- Stethosport (NCT02501694)
- Testing
- Auscultation
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Atrial Fibrillation, Stroke
Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients
This study will compare the two methods 5 days holtermonitoring and 30 days thumb electrocardiogram for detection of atrial fibrillation in stroke patients
- Trial name
- EHOT (NCT02261766)
- Testing
- Holter monitoring and Thumb ECG
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Neoplasms, Venous Thromboembolism
Anti Xa Activity in Cancer Patients Receiving Low-molecular-weight Heparin for Venous Thromboembolism
Low molecular weight heparins (LMWH) are the reference molecule for the long term treatment of venous thromboembolism (VTE) in cancer patients but remains, however, associated with a high risk of recurrent thromboembolism.
- Trial name
- aXa (NCT02898051)
- Where
- 8 sites in France
- Volunteers
- 370 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sturge - Weber Syndrome (SWS)
Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)
Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face.
- Trial name
- NCT00610402
- Testing
- blood sample tear drop sample
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, Irvine
Multiple Myeloma (MM)
A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
The purpose of this study is to evaluate if the addition of SCTC21C to bortezomib, lenalidomide and dexamethasone (VRd) in patients with newly diagnosed multiple myeloma not eligible for transplant will prolong progression-free…
- Trial name
- NCT07297329
- Testing
- SCTC21C, Bortezomib, Lenalidomide
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Sinocelltech Ltd.
Coats Disease
Evaluation of Retinal and Vascular Features in Coats Disease After Intravitreal Injections of Ranibizumab
This study evaluates the retinal and vascular features in patients affected by Coats disease under the effects of Ranibizumab intravitreal injections using optical coherence tomography and optical coherence tomography angiography
- Trial name
- NCT04310631
- Testing
- Ranibizumab Injection
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- Federico II University
Critical Limb Ischemia
Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Ischemia
This is a randomized and single blinded study aimed to compare the efficacy between intramuscular autologous bone marrow mononuclear cells plus mesenchymal stem cell implantation and intramuscular autologous bone marrow…
- Trial name
- NCT01456819
- Testing
- Mononuclear and mesenchymal stem cells, Mononuclear cells
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- National University of Malaysia
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
RATIONALE: Gathering information over time about patients' sense of being a burden on their caregiver, and caregivers' sense of burden on themselves, may help doctors learn more about the desire to die in patients with late-stage…
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Depression, Leukemia
- Trial name
- NCT00770419
- Testing
- medical chart review, questionnaire administration, psychosocial assessment and care
- Sponsor
- Rutgers, The State University of New Jersey
Acute Coronary Syndromes
Revascularisation or Medical Therapy in Elderly Patients With Acute Anginal Syndromes
For octogenarian patients with NSTEMI (non-ST segment elevation myocardial infarction) an invasive-guided strategy will prove superior to a conservative strategy with respect to a combined endpoint of all cause mortality and…
- Trial name
- RINCAL (NCT02086019)
- Testing
- Conservative Arm, Invasive Arm
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Anemia, Leukemia
Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer
RATIONALE: Darbepoetin alfa and epoetin alfa may stimulate red blood cell production and treat anemia in patients who are receiving chemotherapy.
- Conditions
- Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00070382
- Testing
- darbepoetin alfa, epoetin alfa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Heart Failure With Reduced Ejection Fraction; Hypertension
Feasibility and Effectiveness of a Ring-Type Blood Pressure Device (CART-BP) Compared With 24-Hour Ambulatory Blood Pressure Monitoring in HFrEF
This study aims to evaluate the feasibility and diagnostic accuracy of the CART-BP ring-type wearable blood pressure monitoring device in comparison with 24-hour ambulatory blood pressure monitoring (ABPM) in patients with heart…
- Trial name
- RING-HFrEF (NCT07626879)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Keimyung University Dongsan Medical Center
Diabetes Mellitus, Type 2, Hypertension
Evaluation of Blood Pressure Reduction, Safety, and Tolerability of Canagliflozin in Patients With Hypertension and Type 2 Diabetes Mellitus on Stable Doses of Anti-hyperglycemic and Anti-hypertensive Agents
The purpose of this study is to evaluate the effect of canagliflozin (JNJ-28431754) on blood pressure reduction, compared to placebo, in patients with hypertension and type 2 diabetes mellitus and who are on stable doses of…
- Trial name
- NCT01939496
- Testing
- Canagliflozin
- Where
- 57 sites in United States, Puerto Rico
- Volunteers
- 171 people
- Sponsor
- Janssen Scientific Affairs, LLC
Hypertension
Awareness Program on Knowledge Regarding Prevention of Hypertensive Crisis
To determine the effect of planned awareness program on knowledge regarding prevention of hypertensive crisis in hypertensive patients.
- Trial name
- NCT06986746
- Testing
- Hypertension Crisis Awareness Program
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Riphah International University
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.