Clinical trials: Vascular Reactivity
Cardiovascular Disease, Acute Coronary Syndrome
Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention
Patients admitted to hospital with chest pain due to reduced blood flow to heart muscle (diagnosis Acute Coronary Syndrome) can be treated with medication and an angioplasty ± stent procedure, which restores blood flow to the…
- Trial name
- APACS-HPR (NCT01339026)
- Testing
- Prasugrel, Plavix
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Hypertension
Effects of Yoga Training on Cardiovascular Reactivity to Psychological Stress in Patients With Hypertension
The purpose of this study is to examine the effects of 12-week yoga training on blood pressure, heart rate, heart rate variability, arterial stiffness, and total peripheral resistance during rest and psychological stress in…
- Trial name
- NCT03274193
- Testing
- Yoga training program
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Arterial Hypertension, Resistant Hypertension
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity.
- Conditions
- Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
- Trial name
- NCT06169241
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
COVID-19 Vaccine, Corona Virus Infection
Quantification of Binding and Neutralizing Antibody Levels in COVID-19 Vaccinated Health Care Workers Over 1 Year
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic presents a great challenge to global health. The first case was identified in December 2019 in Wuhan, China and since has infected nearly 100 million…
- Conditions
- COVID-19 Vaccine, Corona Virus Infection, Vaccine Adverse Reaction, Vaccine Response
- Trial name
- NCT04910971
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Coronary Artery Disease
Use of a Point-of-Care Platelet Function Assay for the Prediction of Atherothrombotic Events
1. To evaluate the role of VerifyNow test as prognostic marker in routine clinical practice using drug-eluting stents. 2. To determine the add-on-effect of VerifyNow test beyond on conventional risk factors (clinical, lesions, or…
- Trial name
- ASAN-VERIFY (NCT01183754)
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- CardioVascular Research Foundation, Korea
Coagulopathy, Blood Transfusion Complication
Thromboelastography Normal Reference Values in China Hunan Province
The purpose of this study was to establish the normal reference range of Thrombelastogram parameters in Hunan by a multicenter study, and to analyze the specificity of Thrombelastogram detection and the influence of gender, age…
- Trial name
- NCT03146455
- Testing
- no intervention
- Where
- China
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Cardiovascular Disease
The Effects of Alkalised Cocoa on Human Vascular Function
The primary propose of this study is to determine how processing, in particular alkalisation, alters the vascular effects of high-flavanols foods such as cocoa
- Trial name
- NCT01312584
- Testing
- Processed High-flavanol
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy, Postmenopausal Women
Dried Cabernet Grapes and Cardiovascular Risk Markers
This study assesses the acute effects of dried Cabernet grape intake on vascular function and platelet reactivity in postmenopausal women.
- Trial name
- RZN (NCT03065166)
- Testing
- Raisin Treatment, Bagel Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cardiovascular Diseases, Heart Diseases
Social Dominance, Gender, and Cardiovascular Reactivity
To examine biopsychosocial processes that might contribute to the associations among social dominance, gender, and cardiovascular reactivity,.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005522
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypoxia, Brain, Hyperoxia
The Effect of Respiratory Challenge on the BOLD Signal
The purpose of this research study is to better understand how blood flow and metabolism are different between normal controls and patients with disease.
- Conditions
- Hypoxia, Brain, Hyperoxia, Hypercapnia, Hypocapnia
- Trial name
- NCT04258774
- Testing
- Carbon Dioxide
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pruritis, Hypotension Drug-Induced
Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.
The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women.
- Conditions
- Pruritis, Hypotension Drug-Induced, Urinary Retention, Fetal Bradycardia During Labor
- Trial name
- NCT07187427
- Testing
- Spinal analgesia, Epidural Analgesia
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Justine's Hospital