Clinical trials: Vascular Risk
Venous Thromboembolism
Prophylactic Use of Sodium Enoxaparin for Venous Thromboembolism in High-Risk Abdominal Surgery
The purpose of this study is to compare the safety and security and efficacy of sodium enoxaparin Cristália Produtos Químicos Farmaceuticos Ltda - Endocris with Clexane (Sanofi-Aventis) to prevent Venous Thromboembolism in…
- Trial name
- NCT01308528
- Testing
- Sodium enoxaparin, Sodium Enoxaparin clexane
- Where
- 9 sites in Brazil
- Volunteers
- 243 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
Hypertension (HTN), Obesity &Amp; Overweight
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
- Conditions
- Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
- Trial name
- MIND HIIT (NCT07130539)
- Testing
- MIND HIIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Texas Woman's University
Systemic Lupus Erythematosus
Immune Mediators and Metabolites to Stratify Systemic Lupus Erythematosus Patients at High Risk of Cardio Vascular Diseases
Accelerated atherosclerosis is an established complication of systemic autoimmune diseases, particularly SLE. Young female patients with SLE are more likely to develop myocardial infarction than matched healthy controls, and CVD…
- Trial name
- ISLE (NCT04276701)
- Testing
- blood sample, Ultrasonography assessment, questionnaires
- Where
- 6 sites in France, Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
Heart Failure, Diastolic, Heart Failure, Systolic
Network Medicine Approaches to Classify Heart Failure With PReserved Ejection Fraction by Signatures of DNA Methylation and Point-of-carE Risk calculaTors (PRESMET)
Heart failure (HF) is a syndrome, resulting from structural or functional impairment of ventricular filling or ejection of blood.
- Conditions
- Heart Failure, Diastolic, Heart Failure, Systolic, Pulmonary Hypertension, Atrial Fibrillation
- Trial name
- PRESMET (NCT05475028)
- Testing
- RRBS
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Campania Luigi Vanvitelli
Stroke
Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke
The risk of recurrence is greatest immediately after stroke or Transient Ischaemic Attack (TIA). Existing prevention strategies (antithrombotic, lipid/blood pressure lowering, endarterectomy) reduce, not abolish, further events.
- Trial name
- TARDIS (NCT01661322)
- Testing
- Aspirin, Dipyradimole, Clopidogrel
- Where
- United Kingdom
- Volunteers
- 3,096 people
- Sponsor
- University of Nottingham
Asymptomatic Atrial Fibrillation
Subclinical Atrial Fibrillation Home Monitoring in Hypertensive Patients
Atrial fibrillation is a highly prevalent and incidental arrhythmia, often asymptomatic, and frequently detected incidentally or in association with a stroke.
- Trial name
- NCT07058831
- Testing
- Home ECG monitoring
- Where
- Argentina
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Center Rosario British Sanatorium
Hypertension, Diabetes Mellitus
Dissemination of the Cardiovascular Risk Service
The objective of this study is to evaluate the implementation of of a remote, pharmacist-led cardiovascular risk service (CVRS) in 12 large, organizationally and culturally diverse hospitals and health-systems, many with high…
- Trial name
- CVRSLive (NCT03660631)
- Testing
- CVRS Intervention
- Where
- 14 sites in United States
- Volunteers
- 542 people
- Sponsor
- Korey Kennelty
Meningioma
A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
The aim of the study is to compare different strategies for prevention of venous thromboembolism related to intracranial meningioma surgery.
- Trial name
- NCT01941602
- Testing
- prophylactic enoxaparin, non-prophylactic
- Where
- 3 sites in Norway, Sweden
- Volunteers
- 979 people
- Sponsor
- St. Olavs Hospital
Venous Thromboembolism
Evaluating the Risk of Postoperative Venous Thromboembolism in Cervical Cancer Patients
The aim of this study is to develop a machine learning model to accurately predict the risk of venous thromboembolism in patients with cervical cancer after surgery.
- Trial name
- NCT06556953
- Where
- China
- Volunteers
- 1,174 people
- Sponsor
- Haike Lei
Multiple Myeloma and Plasma Cell Neoplasm
Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis
RATIONALE: Drugs such as melphalan, thalidomide, and dexamethasone may be effective in treating patients with primary systemic amyloidosis.
- Trial name
- NCT00089167
- Testing
- filgrastim, dexamethasone, melphalan
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Antiphospholipid Syndrome
Rivaroxaban in Thrombotic Antiphospholipid Syndrome
Primary Study Objective(s) The primary objective is to demonstrate the non-inferiority of Rivaroxaban 20 mg (or 15mgqd in case of moderate renal insufficiency) versus warfarin (INR 2.0-3.0) with respect to the occurrence of the…
- Trial name
- TRAPS (NCT02157272)
- Testing
- Experimental: Rivaroxaban
- Where
- Italy
- Volunteers
- 121 people
- Sponsor
- University of Padova
Coronary Artery Disease (CAD), Peripheral Arterial Disease (PAD)
Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk
Registry to describe the impact in terms of effectiveness and safety of the combination treatment of rivaroxaban 2.5 mg twice daily with aspirin on clinical outcomes and practices in a real-life Dutch patient population that are…
- Trial name
- NCT04753372
- Testing
- Rivaroxaban 2.5 MG [Xarelto]
- Where
- 12 sites in Netherlands
- Volunteers
- 645 people
- Sponsor
- Maatschap Cardiologie Zwolle
Coronary Arteriosclerosis
Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease
This study will measure and compare the levels of endothelial progenitor cells (EPCs) in the blood of people with and without risk factors for atherosclerosis (hardening of the arteries) to see if there is a relationship between…
- Trial name
- NCT00013975
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Aortic Dissection
The Relationship Between ALDH2 and Aortic Dissection
The purpose of this study is to evaluate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.
- Trial name
- RALAD (NCT02630212)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Qilu Hospital of Shandong University
Hypertension, Cardiovascular Risk
Multicomponent Exercise Program in Women With Hypertension
This study tested whether a 12-week supervised multicomponent exercise program is associated with changes in blood pressure, estimated cardiorespiratory fitness, handgrip strength and health-related quality of life in women aged…
- Trial name
- NCT07913971
- Testing
- Multicomponent exercise program
- Where
- Colombia
- Volunteers
- 32 people
- Sponsor
- Universidad Pedagogica Nacional, Colombia
Smoking Status, Genetic Risk Factors
Effect of Smoking Status and Genetic Risk Factors on Restenosis and Efficacy of Clopidogrel After de Novo Percutaneous Coronary Intervention
Restenosis occurs for many different reasons. Over the years, many predictive clinical, biological, genetic, epigenetic, lesion-related, and procedural risk factors for restenosis have been identified.
- Conditions
- Smoking Status, Genetic Risk Factors, Restenosis, Clopidogrel
- Trial name
- NCT03613337
- Testing
- clinical restenosis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Cui Yimin
Hypertensive Disorders of Pregnancy, Postpartum Hypertension
Cardiometabolic Risk in Pregnancy and Postpartum
The goal of this study is to evaluate changes in blood pressure and early cardiovascular risk markers and to determine whether a postpartum education intervention can improve cardiovascular risk monitoring among pregnant women in…
- Conditions
- Hypertensive Disorders of Pregnancy, Postpartum Hypertension, Cardiovascular Disease Risk, High Blood Pressure
- Trial name
- NCT07420465
- Testing
- Postpartum Cardiovascular Disease (CVD) Risk Reduction Program, Enhanced Postpartum Care
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Forgive Avorgbedor
Cardiac Arrest
Cardiac Arrest and Intra Osseous Infusion
the international recommendations don't explain the place of the intraosseous infusion in the reanimation of adult cardiac arrest; the goal of this preliminary study is to inform the delay for obtaining a vascular access by…
- Trial name
- ACCIO (NCT01803971)
- Testing
- Obtention of vascular access in out-of-hospital cardiac arrest patients according to the current strategy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.