Clinical trials: Vascular Surgery
Vascular Surgery
Evaluate the Muscle Protection Effect of Sevoflurane Sedation in Vascular Surgery
Halogenated anaesthetic agents (HAA) may induce protective processes by pre-conditioning the myocardium. All of the literature shows that HAA induce pre-conditioning, thanks to a class effect, and Sevoflurane is the most widely…
- Trial name
- PHAR (NCT03215446)
- Testing
- maintenance of anaesthesia with propofol, maintenance of anaesthesia with sevoflurane
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Vascular Anastomosis Surgery
Post-market Clinical Study to Confirm Safety and Performance of PuraStat® for the Management of Bleeding in Vascular Surgery.
The objective of this post-market clinical follow-up study is to collect medical information on patients implanted with PuraStat®, according to each participating institution's procedures and standards of care.
- Trial name
- NCT03103282
- Testing
- PuraStat®
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- 3-D Matrix Europe SAS
Vascular Diseases, Surgery
Dietary Restriction in Vascular Surgery
A randomized, controlled trial to evaluate patient compliance and biologic mechanisms of a short-term pre-operative Protein-Calorie Restriction (PCR) diet in comparison to a normal ad libitum diet for 4 days before elective…
- Trial name
- DRIVeS (NCT04013412)
- Testing
- Protein-Calorie Restriction
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Brigham and Women's Hospital
Massive Transfusion, Trauma
Australian and New Zealand Massive Transfusion Registry
Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies.
- Conditions
- Massive Transfusion, Trauma, Cardiothoracic Surgery, Gastrointestinal Bleeding
- Trial name
- ANZ-MTR (NCT02863250)
- Where
- Australia
- Volunteers
- 50,000 people
- Sponsor
- Monash University
Bilateral Vascular Groin Surgery
Evaluation of the Effectiveness of a Closed-incision Negative-pressure Therapy (Prevena®) on Bilateral Groin Incision
Closed-incision negative-pressure therapy are medical device that are suspected to reduce groin wound complication in vascular surgery.
- Trial name
- PREVISION (NCT04174183)
- Testing
- Closed-incision Negative-pressure Therapy - Dry dressing
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Central Hospital, Nancy, France
Adjunct to Hemostasis During Vascular Surgery
Efficacy and Safety of TISSEEL Lyo Compared to Manual Compression as an Adjunct to Haemostasis
The primary objective of the study is to evaluate the efficacy of TISSEEL Lyo for haemostasis in patients receiving peripheral vascular prosthetic expanded polytetrafluoroethylene (ePTFE) conduits, as compared to a control arm…
- Trial name
- NCT04083807
- Testing
- TISSEEL Lyo, Manual compression with surgical gauze pads
- Where
- 5 sites in Russia
- Volunteers
- 104 people
- Sponsor
- Baxter Healthcare Corporation
Neoplasms, Surgery--Complications
Resection of the Inferior Vena Cava Due to Tumor Involvement
The involvement of the inferior vena cava (IVC) in advanced abdominal tumors is a surgical challenge, given the high postoperative morbidity and poor long-term prognosis.
- Conditions
- Neoplasms, Surgery--Complications, Vascular Diseases, Vein Disease
- Trial name
- CAVARESECT (NCT04154761)
- Testing
- Resection of inferior vena cava and reconstruction
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Hospital Universitario Infanta Cristina
Vascular Surgery
Association of PeriOPerative Aspirin-ResisTance and CardioVascular Outcome
The aim of our study is to investigate the association between perioperative aspirin resistance and Myocardial Injury after Non-cardiac Surgery (MINS) in patients undergoing vascular surgery.
- Trial name
- POPART-CVO (NCT04053894)
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University Hospital Heidelberg
Cardiac, Aortic Arch Surgery
Brain Vascular Reactivity to Hypothermic Circulatory Arrest With Antegrade Cerebral Perfusion During Aortic Arch Surgery
Many neonates and infants who undergo complex cardiac surgery are affected by neurological developmental delays. Whilst catastrophic events are immediately identifiable from clinical examination or by macro changes on MRI or CT…
- Conditions
- Cardiac, Aortic Arch Surgery, Brain Vascular, Neonates
- Trial name
- NCT03047876
- Testing
- aortic arch surgery
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
General Anesthesia, Vascular Surgery
BNP and Vascular Surgery
Background and rationale of the study: Patients undergoing non-cardiac major surgery show a perioperative cardiac risk and postoperative complications, that can be stratified based on parameters linked to patient's conditions and…
- Conditions
- General Anesthesia, Vascular Surgery, Abdominal Aortic Aneurysm, Natriuretic Peptide, Brain
- Trial name
- BNPinVasc (NCT03926104)
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- University of Parma
Intellectual Frailty of Aging, Cardiovascular Diseases
Assessment of Frailty as a Risk Factor for Cardiac and Vascular Surgery
The purpose of this study is to assess the impact of frailty as a multidimensional risk factor on the outcomes of adult cardiac and vascular surgery.
- Conditions
- Intellectual Frailty of Aging, Cardiovascular Diseases, Myocardial Infarction, Vascular Diseases
- Trial name
- NCT02224222
- Where
- Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Vascular Surgery Patient With PAD / Carotid Stenosis
Perioperative Aspirin Response in Patients Undergoing Vascular Surgery
Reduced antiplatelet activity (low response (LR)/high on-treatment platelet reactivity (HPR)) of aspirin (ALR) or clopidogrel (CLR) is associated with an increased risk of thromboembolic events.
- Trial name
- NCT03587324
- Testing
- Whole blood aggregometry before and after vascular treatment (ASA/ Clopidogrel).
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- St. Josef Hospital Bochum
Post Craniotomy Surgery, Cancer
The Management of Postoperative Craniotomy Pain in Pediatric Patients
The purpose of this prospective, clinical observational trial is to assess the incidence of pain (and analgesia), methods of pain assessment (and by whom), prescribed analgesics, methods of analgesic delivery, and patient/parent…
- Conditions
- Post Craniotomy Surgery, Cancer, Epilepsy, Vascular Malformations
- Trial name
- NCT01576601
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Johns Hopkins University
Lower Limb Vascular Surgery - Femoral Artery Endarteriectomy
Prediction of Femoral Revascularization Quality Using the Somatic NIRS Signal
Despite effective femoral artery endarteriectomy, patients with occlusive arteritis may need complementary stenting of revascularization procedures within the 2 years after the primary surgery because of a poor blood supply in…
- Trial name
- TEA-NIRS (NCT02337920)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Caen
Peripheral Arterial Disease, Vascular Surgery
Remote Ischemic Preconditioning Prior to Vascular Surgery
The investigators have previously shown that elective vascular surgery is a high-risk operation with an anticipated risk of either death or heart attack of 15%.
- Trial name
- CRIPES (NCT01558596)
- Testing
- Preconditioning, Control
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Target Bleeding Site During Peripheral Vascular Surgery
Safety and Efficacy Study of Fibrin Sealant Grifols Evaluated as an Adjunct to Hemostasis
The purpose of this study is to evaluate the safety and hemostasis effectiveness of human plasma-derived fibrin sealant Grifols (FS Grifols) in peripheral vascular surgery.
- Trial name
- NCT00684047
- Testing
- FS Grifols, Manual Compression
- Where
- 19 sites in Canada, Spain and 1 more
- Volunteers
- 239 people
- Sponsor
- Instituto Grifols, S.A.
Vascular Disease, Surgery
Clinical Trial of a Silver Eluting Dressing System
This prospective, multi-institutional randomized clinical trial of a silver ion eluting dressing material compared to standard dry gauze for closed skin incisions after open surgical revascularizations for peripheral vascular…
- Trial name
- SILVER (NCT01229358)
- Testing
- Surgical dressing
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Brigham and Women's Hospital
Surgical Wound Infection, Vascular Surgery
Supplemental Oxygen in Vascular Surgery
The purpose of this study was to test the hypothesis that supplemental postoperative oxygen reduces the risk of surgical wound infection in patients following lower limb vascular surgery.
- Trial name
- NCT00873704
- Testing
- supplemental postoperative oxygen
- Where
- 6 sites in Finland
- Volunteers
- 274 people
- Sponsor
- North Karelia Central Hospital
Cardiothoracic Surgery, Vascular Surgery
A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Surgery
This study will evaluate the safety and efficacy of ABT-719 in patients undergoing high risk major surgery.
- Trial name
- NCT01897519
- Testing
- ABT-719
- Where
- 23 sites in United States, Denmark
- Volunteers
- 56 people
- Sponsor
- AbbVie
Adjunct to Hemostasis in Vascular Surgery (Synthetic Vascular Grafts)
Fibrin Sealant Vascular Surgery Study
The purpose of this study is to evaluate the efficacy and safety of Fibrin Sealant, Vapor Heated, Solvent/Detergent-treated with 500 IU/ml thrombin and synthetic aprotinin (FS VH S/D 500 s-apr) for hemostasis in participants…
- Trial name
- NCT00576420
- Testing
- FS VH S/D 500 s-apr, 60-seconds polymerization time, FS VH S/D 500 s-apr, 120-seconds polymerization time, Manual compression with surgical gauze pads
- Where
- 11 sites in United States
- Volunteers
- 101 people
- Sponsor
- Baxter Healthcare Corporation