Clinical trials: Vascular Surgical Procedures
Myocardial Ischemia, Critical Illness
Bright Light Exposure in Surgical Patients
1. Elucidate the influence of intense light therapy pretreatment in patients undergoing cardiac surgery. We hypothesize that intense light exposure is associated with the peripheral stabilization of Per2 in human buccal swabs and…
- Conditions
- Myocardial Ischemia, Critical Illness, Endothelial Dysfunction
- Trial name
- NCT03822949
- Testing
- Day Light, ICU Intense Light
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Colorado, Denver
Undernutrition
The Role of Preoperative Oral Immunonutrition in Major Vascular Surgery
The role of preoperative oral immunonutrition in major vascular surgery. The mean purpose of this study was to determine the prevalence of post-operative infection complications after major vascular surgery in group of patients…
- Trial name
- NCT00559520
- Testing
- Impact, Oral Impact
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Aneurysm Cerebral
Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy
This study is looking at how taking aspirin regularly affects bleeding during and after brain surgery. Specifically, it focuses on patients who are having elective surgery to clip a brain aneurysm.
- Trial name
- ASPRIN (NCT07086183)
- Testing
- Observation
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Prostate Cancer (Adenocarcinoma), Kidney Cancers
Efficacy and Safety of VasoClip® vs. WeckClip® for Robotic Urologic Surgery
This prospective, randomized, Phase III trial evaluates the efficacy and safety of VasoClip®, a novel polymer surgical clip with a Z-groove and an elastic notch, designed to enhance mechanical grip and prevent slippage.
- Conditions
- Prostate Cancer (Adenocarcinoma), Kidney Cancers, Urothelial Cancer
- Trial name
- NCT07413120
- Testing
- VasoClip®, WeckClip®
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Incheon St.Mary's Hospital
Peripheral Vascular Disease, Peripheral Artery Disease
Platelet Activity in Vascular Surgery for Thrombosis and Bleeding
The proposed PIVOTAL study will examine a panel of platelet/coagulation activity markers during the perioperative period. The goal is to develop a clinically useful assessment of platelet/coagulation activity for risk…
- Conditions
- Peripheral Vascular Disease, Peripheral Artery Disease, Carotid Stenosis, Aortic Aneurysm, Abdominal
- Trial name
- PIVOTAL (NCT01897103)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Thrombus, Embolus
A PMCF Study Confirm the Performance and Safety of the TufTex Over-the-Wire (OTW) Embolectomy Catheters
A PMCF study to confirm the performance and safety of the LeMaitre® TufTex Over-the-Wire Embolectomy Catheter
- Conditions
- Thrombus, Embolus, Occlusion; Vessel
- Trial name
- OTW (NCT05386342)
- Testing
- TufTex Over-the-Wire Embolectomy Catheter
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 112 people
- Sponsor
- LeMaitre Vascular
Cerebral Aneurysm
Multidimensional Evaluation of Patients With Ruptured or Unruptured Cerebral Aneurysm Undergoing Endovascular or Surgical Treatment
Cerebral aneurysms are common changes in intracranial angioarchitecture. Unruptured aneurysms are increasingly identified thanks to the imaging techniques used in daily clinical practice.
- Trial name
- NCT05713825
- Testing
- Endovascular embolization or surgery
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Complications, Cardiovascular Diseases
General Versus Regional Anesthesia in Peripheral Arterial Surgery
This multicenter, prospective, randomized clinical trial aims to compare the effects of spinal (neuraxial) anesthesia with spontaneous ventilation versus general anesthesia with mechanical ventilation on the incidence of…
- Trial name
- GENERA (NCT06953128)
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Brazil
- Volunteers
- 594 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Coronary Artery Disease
Long Term Follow-up of Robotic Assisted Surgical Revascularization
The objectives of the 2-year study are two-fold: 1. To determine the 5-7 year patency rate (rate of open bypass grafts) of the LITA graft of patients who have already had robotically-assisted CABG surgery using CTA and MPS-MIBI…
- Trial name
- ZEUSFUPCTA (NCT00774865)
- Testing
- MIBI and CTA
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Shock, Septic, Hyperlactatemia
Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery
The MostCare system, thanks to the Pressure Recording Analytical Method (PRAM; Vygon, Padua, Italy), provides new hemodynamic parameters of the cardiovascular system.
- Conditions
- Shock, Septic, Hyperlactatemia, Oliguria, Aortic Aneurysm, Abdominal
- Trial name
- RELASTANCE (NCT04388267)
- Testing
- Fluid challenge
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Diabetic Foot Ulcers, Foot Wounds
Santyl vs. Sharp Debridement of Diabetic Foot Wounds
This study tests two different approaches to the removal of dead tissue from the surface of a wound.
- Trial name
- NCT01056198
- Testing
- Santyl, Control
- Where
- 9 sites in United States
- Volunteers
- 48 people
- Sponsor
- Healthpoint
Intracranial Hemorrhage Ruptured Aneurysm
International Subarachnoid Aneurysm Trial II
The purpose of this study is to compare the clinical outcome of surgical clipping and endovascular coiling for ruptured intracranial aneurysms not included in the original ISAT Study.
- Trial name
- ISATII (NCT01668563)
- Testing
- surgical management, Endovascular management
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 1,724 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Venous Insufficiency of Leg, Venous Insufficiency (Chronic)(Peripheral)
Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical Procedure
Endothelial dysfunction is assessed in patients with chronic venous insufficiency of lower limbs (grade C4 according to C - clinical manifestations, E - etiologic factors, A - anatomic distribution of disease, and P - underlying…
- Conditions
- Venous Insufficiency of Leg, Venous Insufficiency (Chronic)(Peripheral), Endothelial Dysfunction
- Trial name
- NCT04180137
- Testing
- Endovenous laser ablation of great saphenous vein (GSV) and microphlebectomy of varicose veins, Pharmacotherapy
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Von Hippel-Lindau Disease
Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease
Von Hippel-Lindau disease (VHL) is an inherited cancer syndrome. Patients are at risk for developing pancreatic cysts and tumors. These tumors are more aggressive in some people than in others.
- Trial name
- NCT00062166
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Cancer Institute (NCI)
Diabetic Ulcers, Venous Leg Ulcer
PMCF Study of Debridement Pad
The design of the study is a clinical trial of Debridement Pad in subjects with superficial, chronic and acute wounds consisting of Diabetic ulcers, Arterial and Venous Leg ulcers, Pressure ulcers, Postoperative wounds healing by…
- Conditions
- Diabetic Ulcers, Venous Leg Ulcer, Arterial Leg Ulcer, Pressure Ulcer
- Trial name
- NCT07255937
- Testing
- Debridement Pad
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- Advanced Medical Solutions Ltd.
Cardiac Surgical Procedures, Hemodynamics
Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery
This multicenter pilot randomized controlled trial will evaluate whether providing treating physicians with a structured hemodynamic assessment influences care after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures, Hemodynamics, Fluid Therapy, Acute Kidney Injury
- Trial name
- UTF-in-CVICU (NCT07792707)
- Testing
- Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm)
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Open Surgery on the Abdominal Aorta
Study of the Size of the Operating Fields Depending on the Morphology of the Patients
This is a prospective, single-centre, observational clinical study. Patients who have not expressed their non-opposition, who are of age and who are undergoing open surgery on the abdominal aorta by laparotomy will be included.
- Trial name
- ABORD-3D (NCT06063395)
- Testing
- open surgery on the abdominal aorta by laparotomy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Geprovas
Myocardial Infarction, Coronary Artery Bypass
Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial
The goal of this clinical trial is to compare two types of exercise prescriptions in cardiac rehabilitation eligible older adults (60 years or older) with heart disease.
- Conditions
- Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure
- Trial name
- PACE SETTER (NCT05925634)
- Testing
- RPE (usual care), GXT+THHR (intervention)
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Baystate Medical Center
Postoperative Thromboembolism
Effect of Tumescent Lidocaine on Platelet Function
The purpose of this study is to evaluate the effect of lidocaine, delivered into subcutaneous tissue for tumescent local anesthesia, on platelet activation following the tumescent liposuction.
- Trial name
- NCT01463280
- Testing
- tumescent lidocaine infiltration
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.