Clinical trials: Vascular Surgical Procedures
Coronary Artery Bypass Graft Surgery (CABG), Patients' Expectations
Optimizing Expectations in Cardiac Surgery Patients
The purpose of this study is to evaluate the potential benefit of targeting patients' expectations before coronary artery bypass graft surgery through a brief psychoeducational intervention.
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Patients' Expectations, Coronary Heart Disease
- Trial name
- NCT01407055
- Testing
- Expectation Manipulation Intervention, Supportive Therapy
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- Philipps University Marburg
Coronary Artery Disease, Aortic Valve Disease
Effect of Early Mobilization on Length of Stay, Recovery and Readmission Rate of Patients After CABG or AVR/MVR Surgery
The present study will investigate the volume and extent of the expected physiological effects of "early mobilization" on the prevention of the clinical illness' detrimental sequelae and on the functional recovery promotion of…
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- NCT04401397
- Testing
- Intensive early mobilization techniques
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Dimitris Chatzitheodorou
Tissue Oxygen Saturation
Tissue Oxygenation of the Tibial Anterior Muscle After Clamping of the Femoral Artery
Ischemic preconditioning is defined as protection from cell damage induced by prolonged ischemia by preceding cycles of short ischemia.
- Trial name
- NIRSFEM (NCT02038062)
- Testing
- Sevoflurane preconditioning
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Schleswig-Holstein
Mitral Valve Insufficiency, Coronary Artery Disease
Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation
Coronary artery bypass grafting (CABG) is a procedure that people with coronary artery disease (CAD) may undergo to increase blood flow to the heart.
- Trial name
- NCT00806988
- Testing
- Mitral Valve Repair, CABG
- Where
- 27 sites in United States, Canada and 1 more
- Volunteers
- 301 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Procedural Sedation
A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.
Very often patients receive medications before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00327392
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 15 sites in United States
- Volunteers
- 123 people
- Sponsor
- Eisai Inc.
Cranial Aneurysm
Navigation Support With Mixed Reality With CORTEXPLORER MED
During the last 15 years, neuronavigation has become an essential neurosurgical tool for pursuing minimal invasiveness and safety.
- Trial name
- CXmed (NCT05269498)
- Testing
- CORTEXPLORER MED
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- cortEXplore GmbH
Coronary Artery Disease
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
This is a research study in women to compare the outcomes of two procedures that restore blood flow to the arteries of the heart.
- Trial name
- RECHARGE:W (NCT06399692)
- Testing
- Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI)
- Where
- 18 sites in United States
- Volunteers
- 600 people
- Sponsor
- Weill Medical College of Cornell University
Acute Aortic Dissection
Mechanism and Early Intervention Research on ALI During Emergence Surgery of Acute Stanford A Aortic Dissection
The morbidity rate of Stanford A type Acute Aortic Dissection（AAD） has been increasing, about 5-10/100,000* per year. Emergency surgery has been the main treatment for Acute Aortic Dissection, however perioperative mortality rate…
- Trial name
- NCT01894334
- Testing
- Ulinastatin, Tranexamic acid, Edaravone
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Ascending Aortic Dilatation, Aortic Aneurysm, Thoracic
Aortic Dilatation Under 5 cm: Genetic Risk Mapping
This retrospective study investigates the prevalence of genetic mutations in patients with ascending aortic dilatation measuring between 4.0 and 5.0 cm-below the standard surgical threshold.
- Conditions
- Ascending Aortic Dilatation, Aortic Aneurysm, Thoracic, Aortic Diseases
- Trial name
- NCT07034430
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Samsun University
Adjunct to Hemostasis in Vascular Surgery (Synthetic Vascular Grafts)
Fibrin Sealant Vascular Surgery Study
The purpose of this study is to evaluate the efficacy and safety of Fibrin Sealant, Vapor Heated, Solvent/Detergent-treated with 500 IU/ml thrombin and synthetic aprotinin (FS VH S/D 500 s-apr) for hemostasis in participants…
- Trial name
- NCT00576420
- Testing
- FS VH S/D 500 s-apr, 60-seconds polymerization time, FS VH S/D 500 s-apr, 120-seconds polymerization time, Manual compression with surgical gauze pads
- Where
- 11 sites in United States
- Volunteers
- 101 people
- Sponsor
- Baxter Healthcare Corporation
Perioperative Complication, Cardiovascular Complication
Cardiovascular Outcomes and Mortality in Vascular Surgical Patients
This is a registry-based study of elective vascular surgical patients undergoing intermediate or high-risk vascular surgical interventions at Groote Schuur hospital, a tertiary academic center, over a 12 month period.
- Trial name
- NCT05208957
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 175 people
- Sponsor
- University of Cape Town
Ischemia Reperfusion Injury
Perioperative Evaluation of MMP-9-TIMP-1 System in Vascular Surgery Regarding Ischemic-reperfusion Injury
The MMP-9-TIMP-1 system has been implicated in many physiological and pathophysiological conditions including vascular surgery related ischemic-reperfusion injury.
- Trial name
- NCT03397732
- Testing
- aorto-bifemoral bypass and aorta stentgraft
- Volunteers
- 20 people
- Sponsor
- University of Pecs
Menopause Surgical
Hormonal Regulation of Cardiometabolic Health Study
The goal of this observational study is to understand how the loss of ovarian function after oophorectomy affects the health and well being of women aged 35-50. The study focuses on four areas: 1.
- Trial name
- HoCa (NCT07406412)
- Testing
- Surgical removal of ovaries, Hormone Replacement Therapy (HRT)
- Where
- 7 sites in Finland
- Volunteers
- 120 people
- Sponsor
- University of Jyvaskyla
Aortic Aneurysm, Postoperative Nausea and Vomiting
AoA Guided Thoracic Epidural Analgesia for Abdominal Aortic Repair
The aim of this randomized trial is to assess the efficacy of analgesia using either thoracic epidural or intravenous infusions for open lumbar infrarenal aortic aneurys repair and compare Numerical Rating Scale (NRS) with…
- Conditions
- Aortic Aneurysm, Postoperative Nausea and Vomiting, Postoperative Pain, Haemodynamic Stability
- Trial name
- AoA-AAA (NCT06609993)
- Testing
- intravenous rescue opioid analgesia using fentanyl, intravenous rescue atropine administration, intravenous rescue urapidil administration
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Michał Stasiowski
General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela
Fully Automated Anesthesia, Analgesia and Fluid Management
Evaluate the feasibility and quality of automated anesthesia, analgesia and fluid management based on a combination of several physiological variables (bispectral index [BIS], stroke volume [SV], and stroke volume variation…
- Conditions
- General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela, Complication of Anesthesia, Drug Delivery System Malfunction
- Trial name
- NCT02886806
- Testing
- BIS XP, Covidien, Ireland, EV-1000 TM, Edwards Lifesciences, Irvine, California, USA
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Erasme University Hospital
Vascular Surgical Procedures, COVID-19
Outcomes of Vascular Surgery in COVID-19 Infection: National Cohort Study
There is an urgent need to understand the outcomes of COVID-19 infected patients who undergo surgery, specially vascular surgery.
- Conditions
- Vascular Surgical Procedures, COVID-19, Postoperative Complications
- Trial name
- Covid-VAS (NCT04333693)
- Testing
- Vascular surgery
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Coronary Artery Disease
The Stent or Surgery (SoS) Trial
This study compared two different methods of restoring blood flow to the heart when there has been a narrowing or blockage in the blood vessels that supply the heart.
- Trial name
- NCT00475449
- Testing
- percutaneous coronary intervention, coronary artery bypass grafting
- Volunteers
- 988 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Syncope, Arrest
Urgent Medical and Surgical Conditions During Flights
The aim of this study is to evaluate the incidence and status of urgent medical conditions. After defining the urgent situations, the investigators will evaluate the adequacy of the standard medical kits and trainings.
- Conditions
- Syncope, Arrest, Vertigo, Pain
- Trial name
- NCT02457455
- Where
- Turkey (Türkiye)
- Volunteers
- 1,312 people
- Sponsor
- Antalya Training and Research Hospital
Intracranial Hemorrhage, Hypertensive
Yiqi Huayu Jiedu Therapy for Non-Surgical Supratentorial Hypertensive Intracerebral Hemorrhage
This multicenter, prospective, double-blind, randomized controlled trial will enroll 902 non-surgical patients with supratentorial hypertensive intracerebral hemorrhage who meet the traditional Chinese medicine syndrome criteria…
- Trial name
- CHAIN2 (NCT07580235)
- Testing
- Yiqi Huayu Jiedu Mixture Intervention
- Volunteers
- 902 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery
The primary objective is to compare the efficacy and safety of once daily (q.d.) subcutaneous (s.c.) injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-ABDO (NCT00679588)
- Testing
- Semuloparin Sodium, Enoxaparin sodium
- Where
- 270 sites in United States, Argentina and 37 more
- Volunteers
- 4,413 people
- Sponsor
- Sanofi