Clinical trials: Vascular Surgical Procedures
Vascular Surgery
Evaluate the Muscle Protection Effect of Sevoflurane Sedation in Vascular Surgery
Halogenated anaesthetic agents (HAA) may induce protective processes by pre-conditioning the myocardium. All of the literature shows that HAA induce pre-conditioning, thanks to a class effect, and Sevoflurane is the most widely…
- Trial name
- PHAR (NCT03215446)
- Testing
- maintenance of anaesthesia with propofol, maintenance of anaesthesia with sevoflurane
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Multivessel Coronary Artery Disease, Acute Coronary Syndrome
Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease
MILESTONE STUDY is dedicated to problems connected with patients with multivessel coronary artery disease and/or with left main narrowing who present symptoms of acute ischemia.
- Trial name
- MILESTONE (NCT01311323)
- Testing
- PCI, CABG
- Where
- 9 sites in Poland
- Volunteers
- 1,000 people
- Sponsor
- American Heart of Poland
Myocardial Bridge of Coronary Artery
Correlates of Left Ventricular Global Longitudinal Strain and Surgical Intervention on Myocardial Bridges
To examine the changes in left ventricular (LV) global longitudinal strain (GLS), using two-dimensional speckle tracking analysis, after left anterior descending (LAD) unroofing, in myocardial bridges (MBs) refractory to optimal…
- Trial name
- NCT04082546
- Testing
- Surgical unroofing of muscle-briged coronary artery
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Myelodysplastic Syndromes, Acute Myeloid Leukemia
Constitution of a Biological Cohort Following Bone Marrow Sampling From MDS or AML Patients and Age-matched Healthy Donors
It is of clinical significance to better characterize the intrinsic defects harbored by mesenchymal stromal cells (MSC) in Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) context, as compared to physiological…
- Conditions
- Myelodysplastic Syndromes, Acute Myeloid Leukemia, Cardio-vascular Surgery
- Trial name
- COSMOS (NCT03233074)
- Testing
- Bone marrow analyses
- Where
- 2 sites in France
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronary Artery Disease, Left Ventricular Cardiac Dysfunction
Clinical Outcome of Coronary Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention in Patients With Severe Left Ventricular Disfunction (CROWN)
The objective of this study is to evaluate the best treatment strategy in patients with critical coronary artery disease and severe left ventricular dysfunction.
- Trial name
- CROWN (NCT07817524)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Reconstructive Surgical Procedures, Plastic Surgery
Leica Microsystems Sponsored Study to Collect and Confirm Clinical Data on the Performance of the GLOW800 Device When Used in Accordance With Its Intended Use.
This post-market clinical follow-up (PMCF) study aims to confirm the safety and performance of the GLOW800 surgical microscope accessory when used in conjunction with the ARveo8x surgical microscope.
- Conditions
- Reconstructive Surgical Procedures, Plastic Surgery, Vascular Surgical Procedure, Cerebrovascular Disorder
- Trial name
- IMED-GLOW800 (NCT07164040)
- Testing
- The GLOW800, a non-contact, non-invasive device, allows the surgical microscope ARveo 8 and ARveo 8X to produce excitation light and resolve fluorescence emission from the fluorescent agent ICG
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 31 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Total Knee Replacement Surgeries
Risk Stratification Procedure for Thromboembolism Prophylaxis
The main objective for this study is validation for the proposed risk stratification tool, by evaluating the clinical outcomes for its use post TKR Surgeries. For this objective, the design that is used is Randomized Trial.
- Trial name
- NCT04031859
- Testing
- acetylsalicylic acid
- Where
- Saudi Arabia
- Volunteers
- 242 people
- Sponsor
- Ministry of Health, Saudi Arabia
Venous Thromboembolism
Effect of the Genotype on Postoperative DVT
Postoperative Venous Thromboembolism Events (VTE) constitute a major source of morbidity and mortality after surgery. The aim of this study was to investigate whether commonly occurring Single Nucleotide Polymorphisms (SNPs) are…
- Trial name
- NCT04940377
- Where
- Denmark
- Volunteers
- 502,505 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arterio-venous Fistula
NIRS Measurement After SCP Block
Peripheral regional anesthesia induces a sympathectomy-like effect with neurovascular changes causing increased arterial blood flow and venodilatation .
- Trial name
- NCT03044496
- Testing
- Supraclavicular nerve block
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Marienhospital Stuttgart
Von Hippel-Lindau Disease
Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease
Von Hippel-Lindau disease (VHL) is an inherited cancer syndrome. Patients are at risk for developing pancreatic cysts and tumors. These tumors are more aggressive in some people than in others.
- Trial name
- NCT00062166
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Cancer Institute (NCI)
Quality of Life
Anesthesia Geriatric Evaluation and Quality of Life After Peripheral Vascular Surgery
A prospective observational cohort study to assess the predictive value of preoperative frailty on postoperative quality of life in peripheral vascular surgery patients.
- Trial name
- AGE-VASC (NCT02820831)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- St. Antonius Hospital
Abdominal Aortic Aneurysm, Carotid Atherosclerosis
Preconditioning Shields Against Vascular Events in Surgery
Major vascular surgery involves operations to repair swollen blood vessels, clear debris from blocked arteries or bypass blocked blood vessels.
- Conditions
- Abdominal Aortic Aneurysm, Carotid Atherosclerosis, Critical Lower Limb Ischaemia
- Trial name
- SAVES-F (NCT02097186)
- Testing
- Remote ischaemic preconditioning
- Where
- 6 sites in Ireland
- Volunteers
- 400 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Oedema, Neuropathy
Optimization of Onpulse Technology for Patients With Post Surgical or Vascular Oedema
This study aims to facilitate further optimization of a neuromuscular electrical stimulation device for use in patients whom are suffering from oedema and neuropathy
- Trial name
- TURBO (NCT02316210)
- Testing
- electrical stimulation
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Firstkind Ltd
Colorectal Cancer, Rectal Tumors
Reconstruction Techniques and Vascular Approach After Laparoscopic Left Hemicolectomy and Rectum Low Anterior Resection
This is an interventional, controlled and randomized single-center clinical trial with patients diagnosed with colorectal cancer that will undergo laparoscopic left hemicolectomy or laparoscopic low anterior resection for rectal…
- Trial name
- TAHR (NCT02746224)
- Testing
- Initially dissection of inferior mesenteric vein, Initially dissection of inferior mesenteric artery, Latero-terminal colorectal anastomosis
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Hypertension, Pulmonary
Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
The aim of the study is to assess safety, tolerability and clinical effects of different doses of riociguat in patients with inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and who are not satisfactorily treated…
- Trial name
- EAS (NCT01784562)
- Testing
- Adempas (Riociguat, BAY63-2521)
- Where
- 102 sites in United States, Austria and 18 more
- Sponsor
- Bayer
Venous Thromboembolism, Pulmonary Embolism
Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery
While blood clots after major cancer surgery are common and harmful to patients, the medications to decrease blood clot risk are seldom used after patients leave the hospital despite the recommendation of multiple professional…
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis, Cancer
- Trial name
- NCT06451003
- Testing
- Exposure to clinical decision support system and education
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Aortic Aneurysm, Abdominal
In Vivo Evaluation of Image Registration Techniques During Endovascular Repair
Fluoroscopy is traditionally used for guidance of endovascular aortic repair (EVAR). In order to minimize exposure to radiation and nephrotoxic contrast medium, it is possible to generate a navigation road map by registering the…
- Trial name
- NCT03116880
- Testing
- Endovascular aortic repair
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Norwegian University of Science and Technology
Aortic Aneurysm, Endoleak
Endoleak Repair Guided by Navigation Technology
The study is aimed at investigating whether repair of endoleak type II can be improved by adding navigation technology. Can this technology increase precision by guiding the needle that punctures through the skin as used during…
- Trial name
- NCT01843322
- Testing
- endoleak repair procedure (navigation technology )
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- Norwegian University of Science and Technology
Second-degree Hemorrhoids
Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease
Hemorrhoidal disease (HD) is one of the oldest and most common proctologic diseases that has been described with an estimated prevalence between 4.4% and 86%.
- Trial name
- SCLEROFOAM (NCT03791775)
- Testing
- Polidocanol foam (Atossisclerol® 3%)
- Where
- Italy
- Volunteers
- 183 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
The ROAMM-EHR Study
In recent years, mobile health (mHealth) apps have promised improved monitoring of health conditions to improve clinical outcomes.
- Trial name
- ROAMM-EHR (NCT06263322)
- Testing
- Actionable remotely generated health data, Non-Actionable remotely generated health data
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida