Clinical trials: Vascular Thrombosis
Stroke, Transient Ischemic Attack
Prospective Evaluation of Carotid Free-floating Thrombus
Hardened plaque located in the carotid arteries can cause stroke or transient ischemic attack (TIA). This type of plaque is linked to unstable free-floating thrombi (FFT).
- Trial name
- NCT02405845
- Testing
- Computed Tomographic Angiogram
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft
Cerebral Microembolism During Hemodialysis
There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound.
- Conditions
- Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft, Cerebral Embolism
- Trial name
- NCT02021045
- Testing
- Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Renal Insufficiency, Chronic, Graft Occlusion, Vascular
External Ionizing Radiation to Prevent Restenosis on Haemodialysis Vascular Access
Although ionizing radiations have been proposed for the prevention of intimal hyperplasia in coronary and peripheral arteries, information is lacking on how irradiation may prevent neointimal smooth-muscle cell proliferation and…
- Conditions
- Renal Insufficiency, Chronic, Graft Occlusion, Vascular, Thrombosis, Intimal Hyperplasia
- Trial name
- RASTA (NCT00379366)
- Testing
- External ionizing radiations
- Where
- 5 sites in France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease
Clopidogrel Resistance and the Possibility of Its Affection
The purpose of the study is to determine, whether the resistance to clopidogrel could be affected by higher doses of this drug, or by replacement of clopidogrel with another ADP-antagonist ticlopidine.
- Trial name
- NCT00839345
- Testing
- clopidogrel
- Where
- Czechia
- Sponsor
- Charles University, Czech Republic
Venous Thromboembolism
Computerized Registry of Patients With Venous Thromboembolism (RIETE)
The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a multidisciplinary Project initiated in march 2001 and consisting in obtaining an extensive data registry of consecutive patients with venous…
- Trial name
- RIETE (NCT02832245)
- Where
- 305 sites in United States, Argentina and 27 more
- Volunteers
- 120,000 people
- Sponsor
- Manuel Monreal
Atrial Fibrillation
A Pilot Study on Edoxaban for the Resolution of Left Atrial Thrombosis in Patients With Non-valvular Atrial Fibrillation
Isolated reports have indicated that complete Left Atrial or Left Atrial Appendage thrombus resolution may be achieved also with use of oral Factor Xa inhibitors, which have demonstrated the same efficacy but a better safety…
- Trial name
- NCT03489395
- Testing
- Edoxaban
- Where
- 8 sites in Italy
- Volunteers
- 25 people
- Sponsor
- Raffaele De Caterina
Venous Thromboses
Intermittent Pneumatic Compression of the Upper Extremity for Post-Operative VTE Prophylaxis
Venous thromboembolism (VTE) is an important cause of morbidity and mortality following surgery.A combination of chemical and mechanical prophylaxis using lower extremity compression devices (CD) is recommended in patients who…
- Trial name
- NCT04341272
- Testing
- Intermittent Pneumatic Compression Device (FDA approved)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Pulmonary Embolism
Mechanical Thrombectomy With the FlowTriever Device in Acute Pulmonary Embolism - a Retrospective Analysis
International guidelines recommend intravenous thrombolysis (IVT) for high-risk pulmonary embolism (PE). In high-risk PE where IVT is contraindicated or has failed, surgical embolectomy or catheter-directed intervention (CDI) is…
- Trial name
- NCT06187987
- Testing
- Mechanical thrombectomy, Intravenous thrombolysis
- Where
- Sweden
- Volunteers
- 132 people
- Sponsor
- Kristina Svennerholm
Pulmonary Embolism, Obesity
Low-dose CT Angiography in the Detection of Acute Pulmonary Embolism: Validation in an Obese Population
Pulmonary embolism is a common pathology in the general population, whose suspicion is based on the clinical and dosage of D-dimers in particular.
- Conditions
- Pulmonary Embolism, Obesity, CT Scanner
- Trial name
- NCT04018014
- Testing
- CT angiography
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Clermont-Ferrand
Oxidative Stress, Inflammation
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary alterations linked to air pollution
- Conditions
- Oxidative Stress, Inflammation, Blood Pressure, Vasoconstriction
- Trial name
- NCT03255187
- Testing
- Fish oil supplementation, Sunflower seed oil supplementation
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fudan University
Retinal Vein Occlusion, Macular Edema
Post Market Surveillance of OZURDEX® for Branch Retinal Vein Occlusion (BRVO) and Central Retinal Vein Occlusion (CRVO)
This multicenter observational study will assess the efficacy and tolerability of OZURDEX® in clinical practice, and will assess the time at which patients are considered for retreatment.
- Trial name
- NCT01568021
- Testing
- No Intervention
- Where
- 3 sites in Denmark, Norway and 1 more
- Volunteers
- 100 people
- Sponsor
- Allergan
Central Venous Catheter Thrombosis
The Relationship Between the Lack of AT-Ⅲ, PC, PS Activity and PICC-related Thrombosis
PICC related venous thrombosis (PICC-RVT) is one of the common complications of PICC and the main cause of unplanned extubation.
- Trial name
- NCT04535206
- Testing
- Venous blood collecting and test and ultrasound screening
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atrial Fibrillation, Deep Vein Thrombosis
Genotype-Guided Warfarin Therapy Trial
The purpose of the investigators' study is to determine the clinical utility of a warfarin-dosing algorithm that incorporates genetic information (VKORC1 and CYP2C9 alleles) for adult patients initiating warfarin therapy.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism, Artificial Heart Valve
- Trial name
- WARFPGX (NCT00904293)
- Testing
- Genotype-guided dose determination, Non-genotype guided warfarin dosing
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of North Carolina, Chapel Hill
Pulmonary Embolism, Pulmonary Thromboembolisms
Catheter-Directed Thrombolysis Versus Anticoagulation Monotherapy in Intermediate-High Risk PE
In an open-label parallel groups blinded-endpoint randomized clinical trial, the investigators aim to assess the safety and efficacy of conventional catheter-directed thrombolysis (CDT) vs anticoagulation monotherapy on outcomes…
- Conditions
- Pulmonary Embolism, Pulmonary Thromboembolisms, Embolism, Pulmonary, Right Ventricular Dysfunction
- Trial name
- CANARY (NCT05172115)
- Testing
- Conventional catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rtPA), Enoxaparin
- Where
- Iran
- Volunteers
- 94 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Pulmonary Embolism
Contribution of Lower Limb Venous Colour Doppler Ultrasound in the Diagnosis of Pulmonary Embolism Recurrence
Venous thromboembolic disease is a clinical entity including pulmonary embolism (PE) and deep vein thrombosis (DVT). It is a chronic disease with 30% recurrence rate at 10 years.
- Trial name
- RECHOPE (NCT05413317)
- Testing
- Color Doppler Ultrasound
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pulmonary Embolism, Chronic Obstructive Pulmonary Disease
Pulmonary Embolism in Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine the prevalence of pulmonary embolism in our population of Chronic Obstructive Pulmonary Disease (COPD) patients admitted to hospital with dyspnea.
- Trial name
- NCT01318174
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Sykehuset Innlandet HF
Venous Thrombosis
JETi Lower Extremity Venous Thrombosis
The JETi Registry is a prospective, single-arm, multicenter study to collect real-world data on the safety, performance, and clinical benefits of the JETi System for the treatment of acute and subacute thrombosis in the…
- Trial name
- JETiRegistry (NCT07027878)
- Testing
- JETi lower extremity venous thrombosis
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 121 people
- Sponsor
- Abbott Medical Devices
Venous Thrombosis
Comparison of Arixtra vs. Lovenox to Prevent Blood Clots in Medically Ill Patients
A total of 50 patients >40 yrs of age with an expected hospital stay in the Medical Intensive Care or Regional Heart Unit at LVH Muhlenberg of 6 days or longer will be enrolled.
- Trial name
- BRiEF (NCT00521885)
- Testing
- Arixtra (Fondaparinox) 2.5 mg SC Daily, Lovenox 40mg SC Daily
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Lehigh Valley Hospital
Venous Thromboembolism, Venous Thrombosis
Intermittent Pneumatic Compression in Surgical Patients at Extremely-high Risk for Venous Thromboembolism
The aim of the study is to evaluate efficacy and safety of venous thromboembolism prophylaxis by the combination of graduated compression stockings (GCS), standard doses of low-molecular-weight heparins (LMWH) and sequential…
- Trial name
- IPCSUPER (NCT03044574)
- Testing
- SCD, GCS, LMWH
- Where
- 2 sites in Russia
- Volunteers
- 407 people
- Sponsor
- Pirogov Russian National Research Medical University
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