Clinical trials: Vascular Thrombosis
Pulmonary Embolism
Ultrasound-assisted, Catheter-directed Thrombolysis for Acute Intermediate-high-risk Pulmonary Embolism
The purpose of this retrospective and prospective multicenter study is to evaluate the incidence of pulmonary hypertension (PH) within 6 months from ultrasound-assisted, Catheter-directed Thrombolysis for acute intermediate…
- Trial name
- USAT IH-PE (NCT06143969)
- Testing
- ultrasound-assisted, catheter-directed thrombolysis
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Niguarda Hospital
Hepatocellular Carcinoma Non-resectable
Lenvatinib Plus DEB-TACE With/Without FOLFOX-HAIC for Large HCC With PVTT
This multicenter retrospective study evaluated consecutive patients with large HCC and PVTT who received lenvatinib plus DEB-TACE with/without FOLFOX-HAIC between July 2019 and June 2021.
- Trial name
- NCT06265883
- Testing
- Len+DEB-TACE+HAIC, Len+DEB-TACE
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Venous Thromboembolism, Arterial Thromboembolism
A Universal Electronic Health Record-based IMPROVE DD VTE Risk Assessment Model for the Prevention of Thromboembolism in Hospitalized Medically Ill Patients
This study will be a multicenter clustered randomized trial of patients in hospitals in which a universal "SMART on FHIR" platform-based EHR-embedded IMPROVE DD VTE clinical prediction rules (CPRs) with electronic order entry has…
- Trial name
- NCT04768036
- Testing
- IMPROVE DD VTE Tool
- Where
- 5 sites in United States
- Volunteers
- 10,699 people
- Sponsor
- Northwell Health
Stroke, DVT
Soft Robotic Sock Intervention for Robot-assisted Ankle-foot Mobility in Post-stroke Patients
Stroke is closely associated with high mortality among patients in hospitals and immobility leading development of deep vein thrombosis (DVT) leading to pulmonary embolism (PE) and Venous thromboembolism (VTE) and/or ankle joint…
- Conditions
- Stroke, DVT, Ankle Contracture
- Trial name
- NCT05491109
- Testing
- Venous Assistance and Contracture Management System (VACOM)
- Where
- Singapore
- Volunteers
- 19 people
- Sponsor
- National University Hospital, Singapore
Pulmonary Embolism
Air Versus Oxygen for Intermediate-Risk Pulmonary Embolism (AIRE)
The primary objective is to evaluate the efficacy of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism.
- Trial name
- AIRE (NCT04003116)
- Testing
- Oxygen gas
- Where
- 7 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Ministry of Health, Spain
Active Cancer and Symptomatic or Incidental Pulmonary Embolism Without HESTIA Criteria
Home Treatment of Patients With Active Cancer and Acute Pulmonary Embolism Without HESTIA Criteria.
Main objective of this multisite randomised study aims to demonstrate in patients with active cancer and symptomatic or incidental PE without HESTIA criteria, that home treatment is non-inferior to hospitalisation as regards the…
- Trial name
- HOME-PEK (NCT07315347)
- Testing
- Home-treatment group
- Where
- 20 sites in France
- Volunteers
- 824 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Retinal Vein Occlusion
Correlation Between the Visual Acuity & the OCT Pattern of Macular Edema Secondary to RVO
Correlation between changes observed in OCT and VA in patients with retinal vein occlusion whether the patient's VA improves when macular edema improves in OCT or not ??
- Trial name
- NCT03489915
- Testing
- OCT
- Volunteers
- 30 people
- Sponsor
- Assiut University
Deep Venous Thrombosis
Evaluation of Long-Term Sequelae After Thrombophlebitis, i.e. Deep Venous Thrombosis of the Lower Extremities
The purpose of the study was to evaluate efficacy and safety of the new acute treatment of deep venous thrombosis by use of low-molecular-weight heparin compared with standard treatment using unfractionated heparin, especially…
- Trial name
- NCT00628576
- Testing
- unfractionated heparin, Tinzaparin (Leo)
- Where
- Denmark
- Volunteers
- 99 people
- Sponsor
- Aalborg University Hospital
Nephrotic Syndrome
Role of PACAP in Nehprotic Syndrome
This study will identify the role of PACAP (pituitary adenylate cyclase-activating polypeptide) deficiency in patients with nephrotic syndrome.
- Trial name
- NCT01411982
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Thromboembolism
Clotting Genetic Variants, Hormones, and Venous Thrombosis
To identify genetic variants in 12 key blood clotting proteins that may modify the risk of venous thromboembolism in users of hormone replacement therapy.
- Trial name
- NCT00094185
- Volunteers
- 1,000 people
- Sponsor
- University of Washington
Pulmonary Embolism, Venous Thromboembolism
Study of IVC Filter Retrieval With the Günther Tulip Vena Cava Filter
The purpose of this study is to test the hypothesis that the Günther Tulip Vena Cava Filter can be removed after a period of implantation, when implanted in patients for the prevention of pulmonary thromboembolism.
- Trial name
- NCT00196118
- Testing
- Günther Tulip Vena Cava Filter
- Where
- 17 sites in United States
- Volunteers
- 800 people
- Sponsor
- Cook Group Incorporated
Postpartum Hemorrhage, Venous Thromboembolism
Haemorrhages and Thromboembolic Venous Disease of the Postpartum
The aim of this study is to evaluate the frequencey and the determinants of postpartum major complications (hemorrhage and thrombosis) up to 3 months after delivery in the maternity hospitals of Finistère (Bretagne - France)
- Trial name
- HEMOTHEPP (NCT02443610)
- Where
- 6 sites in France
- Volunteers
- 20,241 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Patients With Atrial Fibrillation at Risk for Thrombus Formation, Thromboembolism, Stroke
Registry on WATCHMAN Outcomes in Real-Life Utilization
The WATCHMAN LAA Closure Technology is designed to prevent embolization of thrombi that may form in the LAA, thereby preventing the occurrence of ischemic stroke and systemic thromboembolism.
- Trial name
- EWOLUTION (NCT01972282)
- Testing
- WATCHMAN Left Atrial Appendage Closure
- Where
- 47 sites in Belgium, France and 11 more
- Volunteers
- 1,025 people
- Sponsor
- Boston Scientific Corporation
Vein Collapse, Vein Thrombosis
TenTaTorch: Venepuncture Made Easy
Venepuncture can be challenging, especially in patients with co-morbidities that predispose them to have inaccessible veins. Multiple unsuccessful venepuncture attempts compromise patient care.
- Conditions
- Vein Collapse, Vein Thrombosis, Vein; Tortuous, Vein Disease
- Trial name
- NCT03202238
- Testing
- Conventional, Veinlite, TenTaTorch
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Pulmonary Embolism
PEITHO Pulmonary Embolism Thrombolysis Study
Heparin is the reference therapy for most patients with pulmonary embolism. Some patients with sub-massive pulmonary embolism defined by normal blood pressure and dysfunction of the right ventricle have a higher mortality risk.
- Trial name
- PEITHO (NCT00639743)
- Testing
- tenecteplase (group A)
- Where
- 12 sites in Austria, Belgium and 10 more
- Volunteers
- 1,005 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thrombosis Cardiac, Atrial Septal Defect
Cerebral Microembolization Associated With PFO Closure
This study aims to investigate (1) the de novo cerebral microembolization in patients who undergo transcatheter closure of PFO or ASD, and (2) evaluate the relationship between de novo cerebral microembolization and in situ…
- Conditions
- Thrombosis Cardiac, Atrial Septal Defect, Patent Foramen Ovale (PFO)
- Trial name
- NCT06347276
- Testing
- PFO occluder; ASD occluder
- Where
- China
- Volunteers
- 800 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cardiac Pacing, Complications
Prevention of Venous Thrombosis After Permanent Transvenous Leads Implantation
The aim of this study was to compare the safety and efficacy of warfarin versus placebo, administered for 6 months, in the prevention of thromboembolic complications after transvenous cardiac devices implantation in high-risk…
- Conditions
- Cardiac Pacing, Complications, Venous Thrombosis
- Trial name
- NCT00621491
- Testing
- Warfarin
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Antithrombin III Deficiency
Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery
Patients with hereditary antithrombin deficiency are at increased risk of venous thrombosis and pulmonary embolism, particularly during certain high risk procedures.
- Trial name
- NCT00110513
- Testing
- Recombinant human antithrombin (rhAT)
- Where
- 17 sites in United States, Australia and 6 more
- Volunteers
- 18 people
- Sponsor
- rEVO Biologics
Embolism, Pulmonary
Detection of Pulmonary Embolism With Low-dose CT Pulmonary Angiography
Computed tomography pulmonary angiography (CTPA) is the imaging method of choice to rule out acute pulmonary embolism based on its high sensitivity and specificity.
- Trial name
- REDOPED (NCT01258140)
- Testing
- Computed tomography pulmonary angiography
- Where
- Switzerland
- Volunteers
- 504 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thrombus
Accuracy of the 64 Slices Computed Tomography for the Diagnosis of Left Atrial Appendage Thrombus
Transoesophageal echocardiography (TEE) is considered as the gold standard method for detection of left atrial appendage (LAA) thrombus but is a semi-invasive investigation.
- Trial name
- THROMBI-SCAN (NCT01147796)
- Testing
- computed tomography
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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