Clinical trials: Vascular Thrombosis
ST-segment Elevation Myocardial Infarction
Thrombus Aspiration in Patients With STEMI
This is a prospective, randomized study with blinded outcome assessment, comparing routine manual thrombus aspiration with no aspiration in patients with acute ST-segment elevation myocardial infarction (STEMI) underwent…
- Trial name
- NCT02606435
- Testing
- percutaneous coronary intervention (PCI), thrombus aspiration
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Neoplasms, Embolism
Anticoagulation in Patients With Venous Thromboembolism and Cancer
This study is a retrospective analysis of observational cohorts using data from prospectively collected administrative/claims data to investigate treatment patterns,healthcare resource utilisation (HCRU), direct and indirect…
- Trial name
- VICTORIE (NCT04618913)
- Testing
- Apixaban, Rivaroxaban, Edoxaban
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Pfizer
Deep Vein Thrombosis
Comparison Study of CoaguChek XS PT and Laboratory Innovin PT by NTUH Lab Medicine
Comparison Study of CoaguChek XS PT and Laboratory Innovin PT by NTUH Lab Medicine
- Trial name
- NCT00867646
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Retinal Vein Occlusion
Safety and Efficacy of Dexamethasone (OZURDEX®) Intravitreal Implant in Korea
This study is a Post-Market Surveillance study in Korea to evaluate the safety and efficacy of dexamethasone 700 ㎍ (OZURDEX®) intravitreal implant used to treat Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion, or…
- Trial name
- NCT01976650
- Testing
- dexamethasone 700 ㎍ intravitreal implant
- Where
- South Korea
- Volunteers
- 724 people
- Sponsor
- Allergan
Clotting and Bleeding Disorders, Child Development
Determination of ClotPro Paediatric Reference Range Study
A new thromboelastometry analyser (ClotPro, Enicor GmbH, Munich, Germany) with improved technology was developed. This device has an improved new-generation viscoelastometric testing technique and enables the detection and…
- Conditions
- Clotting and Bleeding Disorders, Child Development, Infant Development, Coagulopathy
- Trial name
- NCT04190615
- Testing
- thromboelastometry test (TEM test)
- Where
- Slovakia
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- National Institute of Children's Diseases, Slovakia
DVT of Legs
Deep Venous Thrombosis and Long Term Complications
In this cohort study, the investigators will investigate the concentration of biomarkers, e.g., inflammatory, anti-inflammatory, immunological, senescent, biochemical ratio-calculations, blood cell type, and and long term…
- Trial name
- NCT05789108
- Testing
- Blood sample and Ultrasound examination
- Where
- Denmark
- Volunteers
- 178 people
- Sponsor
- Ove Andersen
Myeloproliferative Neoplasm
Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)
Myeloproliferative Neoplasms (MPN) are associated with an increased risk of thrombosis. Platelets, red blood cells (RBC), leukocytes and endothelial cells are involved in these complications.
- Trial name
- CLOJAK (NCT05839717)
- Testing
- Blood sampling
- Where
- 11 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Thrombosis
CV004-007 Thrombosis Chamber Study
The purpose of this study is to determine whether BMS-986120, aspirin, or aspirin and clopidogrel decrease blood clotting.
- Trial name
- NCT02439190
- Testing
- BMS-986120, Aspirin, Clopidogrel
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Atrial Fibrillation, Thromboembolism, Venous
DOCE Study Interaction Between Direct Oral Anticoagulants and Drug-metabolizing Enzyme Inducers
Aim of the study is to investigate whether the influence of drugs inducing of CYP 3A4 isoenzyme of CYP450 and P-gp transporter significantly affect plasma levels of DOACs in patients with NVAF and venous thromboembolism
- Trial name
- NCT05750680
- Testing
- DOACs
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Venous Thrombosis
A Comparison of the Effects of Neuromuscular Electrical Stimulation and Intermittent Pneumatic Compression on Blood Flow in the Lower Limb
Deep Vein Thrombosis (DVT) is a life threatening condition and a serious concern among hospitalized patients, with death occurring in approximately 6% of cases.
- Trial name
- NCT01894997
- Testing
- Neuromuscular electrical stimulator, AV Impulse System Model 6000
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Atrial Fibrillation, Left Atrial Thrombosis
Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon
This is a single-center, randomized, two treatment groups, open, phase IV clinical study in subjects with atrial fibrillation and left atrial thrombus.
- Trial name
- NCT02591225
- Testing
- Dabigatranetexilate, Phenprocoumon
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Ulm
STEMI
Effectiveness Evaluation in Thrombus Aspiration in Patients With STEMI and High Thrombotic Load
This study intends to evaluate thrombus on the basis of different methods for evaluating thrombus load The effect of aspiration on the prognosis of STEMI patients with high thrombotic load Provide a basis for the standardized use…
- Trial name
- NCT05043597
- Testing
- Thrombus aspiration
- Where
- China
- Volunteers
- 3,838 people
- Sponsor
- Shenzhen People's Hospital
Pulmonary Embolism
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath Condensate
In this study, a new, non-invasive method for diagnosis of pulmonary embolism (PE) will be tested. In pre-clinical studies, we have identified 151 putative biomarkers for pulmonary embolism in the exhaled breath condensate (EBC).
- Trial name
- NCT04010760
- Testing
- Test of biomarkers for PE in EBC
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Surgical Procedure, Non-cardiac, Cardiovascular Disease Patients
Perioperative Ischemia Versus Perioperative Bleeding During Non-cardiac Surgery in Cardiac Patients
The aim of the study is to analyze the present use of antithrombotic therapy on a large cohort of consecutive cardiacs undergoing non-cardiac surgery.
- Conditions
- Surgical Procedure, Non-cardiac, Cardiovascular Disease Patients, Perioperative Period
- Trial name
- PRAGUE-14 (NCT01897220)
- Where
- 2 sites in Czechia
- Volunteers
- 1,200 people
- Sponsor
- Charles University, Czech Republic
Pulmonary Embolism
Effects of Information and Breathing Technique - for Patients With Respiratory Pain in Acute Pulmonary Embolism.
Acute pulmonary embolism (PE) is a serious disease and the third most common cardiovascular disease following myocardial infarction and stroke. The most common symptoms of acute PE are breathlessness and respiratory pain.
- Trial name
- NCT03375723
- Testing
- Information on anatomy and physiology, and breathing technique, Usual care treatment
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Thromboembolic Event
Elaboration of a Prioritization Score for Pharmaceutical Interviews in Patients Treated With Oral Anticoagulants
Oral anticoagulants have a prominent place in the strategy of prevention and treatment of thromboembolic diseases, especially in patients with atrial fibrillation.
- Trial name
- NCT06100380
- Testing
- Survey
- Where
- France
- Volunteers
- 197 people
- Sponsor
- CHU de Reims
Acute DVT of Lower Extremity
Recanalization Rate of Acute DVT
Rporting and evaluation of the rate of recanalization of acute DVT of the lower limb at one year follow-up comparing the results of using NOACs vs. conventional treatment.
- Trial name
- NCT06145269
- Testing
- New oral anticoagulant (rivaroxaban) and Marevan (warfarin)
- Volunteers
- 100 people
- Sponsor
- Assiut University
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery
The primary objective was to compare the efficacy of once daily [q.d] subcutaneous [s.c.] injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-HIP2 (NCT00721760)
- Testing
- Enoxaparin sodium, Semuloparin sodium
- Where
- 25 sites in United States, Argentina and 23 more
- Volunteers
- 1,003 people
- Sponsor
- Sanofi
Thromboembolism
Safety, Pharmacokinetics, Biodistribution, and Diagnostic Performance of [18F]GP1 PET in Thromboembolism
[18F]GP1 targets platelet GPIIb/IIIa receptor in thrombus. [18F]GP1 PET/CT imaging will noninvasively assess thrombus in whole body with good sensitivity with information of thrombus.
- Trial name
- NCT02864810
- Testing
- [18F]GP1
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Asan Foundation
Heparin-Induced Thrombocytopenia, Thrombosis
Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure
The purpose of this study is to determine the HIT-antibody generation without prior heparin-exposure in patients undergoing orthopedic surgery.
- Trial name
- NCT01102790
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
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