Clinical trials: Vasoconstriction
Autonomic Nervous System Imbalance, Blood Pressure
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
- Conditions
- Autonomic Nervous System Imbalance, Blood Pressure, Inflammation, Vasoconstriction
- Trial name
- NCT02238028
- Testing
- Wear respirator
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fudan University
Type 2 Diabetes Mellitus
Effect of DPP4 Inhibition on Vasoconstriction
The purpose of this study is to understand how dipeptidyl peptidase IV (DPP4) inhibition in diabetics affects hemodynamic parameters and sympathetic activation in the setting of increasing concentrations of neuropeptide Y, an…
- Trial name
- NCT02639637
- Testing
- Sitagliptin, Neuropeptide Y, Enalaprilat
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Vanderbilt University
Raynaud Phenomenon, Systemic Sclerosis
Cold Challenge With C21 in RP
This is a randomised, double-blind, placebo-controlled, cross-over phase 2 trial investigating the effect of C21 on cold-induced vasoconstriction in subjects with Raynaud's phenomenon secondary to systemic sclerosis.
- Trial name
- NCT04388176
- Testing
- C21
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Vicore Pharma AB
Oxidative Stress, Inflammation
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary alterations linked to air pollution
- Conditions
- Oxidative Stress, Inflammation, Blood Pressure, Vasoconstriction
- Trial name
- NCT03255187
- Testing
- Fish oil supplementation, Sunflower seed oil supplementation
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fudan University
Vasoconstriction
Evaluation of the Vasoconstriction Properties of MC2-01 Cream
The objective of this trial is to compare the vasoconstriction potential
- Trial name
- NCT03758365
- Testing
- MC2-01 Cream, Clobetasol Propionate 0.05% Lotion, Betamethasone Dipropionate 0.05% Cream
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MC2 Therapeutics
Chronic Sinusitis
Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery
The purpose of our study is to assess the effect of topical vasoconstriction (cocaine 4% versus adrenaline 1/1000) on the surgical field during endoscopic sinus surgery.
- Trial name
- NCT01706952
- Testing
- Cocaine, Adrenaline
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Marc Tewfik
Emphysema
Hypoxic Pulmonary Vasoconstriction Pilot Study
The purpose of this study is to determine if the events leading to smoking-associated centrilobular and paraseptal emphysema are caused by a failure of the lungs' inherent mechanisms to block hypoxic pulmonary vasoconstriction…
- Trial name
- NCT03733470
- Testing
- Sildenafil study group
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric A. Hoffman