Clinical trials: Vasomotor Symptoms, open to volunteers
Postmenopausal Symptoms, Hot Flashes
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms…
- Trial name
- START (NCT06030388)
- Testing
- Strength training, High-intensity aerobic training
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Linkoeping University
Vasomotor Symptoms, Prostate Cancer
A Trial on Fezolinetant for Vasomotor Symptoms in Men Receiving Androgen Deprivation Therapy (ADT)
This is a randomized, double-blind, placebo-controlled, parallel-group, multicenter clinical study to investigates the efficacy of fezolinetant in men undergoing ADT for prostate cancer in alleviating Vasomotor syndromes.
- Trial name
- NCT07568236
- Testing
- Fezolinetant
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- Chinese University of Hong Kong
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Hot Flashes
A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause
This study is for women in India who are going through menopause. They have symptoms including hot flashes and night sweats (also known as vasomotor symptoms or VMS).
- Trial name
- NCT07829653
- Testing
- Fezolinetant
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Prostate Cancer, Hot Flashes
A Feasibility Study of Biometric Measurements Via Wearable Smart Watch Technology for Evaluation of Vasomotor Symptoms in Patients Treated With Androgen Deprivation Therapy for Prostate Cancer (Prostate 007)
The purpose of this study is to find out if patients with prostate cancer who have vasomotor symptoms, commonly called hot flashes, from their Androgen Deprivation Therapy (ADT) will consistently wear a smartwatch device to track…
- Trial name
- BioWEAR (NCT07535541)
- Testing
- VMS logging
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Virginia
Perimenopause, Menopause
The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.
The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women.
- Trial name
- NCT07135232
- Testing
- Sarmentosin - L- theanine, Resistance Training
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Vasomotor Symptoms
Efficacy of CL25216 on Vasomotor Symptoms in Women During Perimenopause
This study is to evaluate the effects of CL25216 on vasomotor symptoms in women during Perimenopause. Enrolled subjects will receive either CL25216 - 250 mg/day or placebo.
- Trial name
- NCT07112651
- Testing
- CL25216
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ApexCPG LLC
Vasomotor Symptoms (VMS) Associated With Menopause
An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Symptoms in United States
Menopause is a natural stage in a woman's life happening between ages 45 and 55. It is often associated with disruptive symptoms like hot flashes and sleep disturbances that can affect up to 8 out of 10 women and make daily life…
- Trial name
- RELIEF (NCT07490431)
- Testing
- No intervention
- Volunteers
- 2,400 people
- Sponsor
- Bayer
Menopause, Vasomotor Symptoms (VMS)
Waning Moon: A Whole Person Health Intervention Designed by and for Urban Menopausal American Indian/Alaska Native Women
This study tests the feasibility and acceptability of Waning Moon, a culturally tailored menopause health intervention developed in partnership with the Urban Indian Center of Salt Lake (UICSL) for American Indian/Alaska Native…
- Conditions
- Menopause, Vasomotor Symptoms (VMS), Women's Health, Health Disparities
- Trial name
- NCT07713095
- Testing
- Waning Moon
- Volunteers
- 30 people
- Sponsor
- University of Utah
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
This is a phase II, randomized, double-blinded, placebo-controlled trial designed to evaluate the efficacy of fezolinetant (45 mg a day) vs.
- Trial name
- NCT06917313
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Yale University
Menopause, Menopausal Vasomotor Symptoms
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms
Given the impact that hot flashes and night sweats can have on daily life during the menopausal transition, our team has developed a therapist-guided online cognitive behavioural therapy (CBT)- based program to help individuals…
- Trial name
- ICBT-Meno-VS (NCT07873177)
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Menopausal Symptoms, Physical Activity and Sedentary Behavior
Prevalence of Menopause-associated Symptoms Throughout the Menopausal Transition in Women Aged 40 to 70 Residing in Spain and Its Relationship With Physical Activity - MdH Study
The goal of this observational study is to learn about menopause-related symptoms in women aged 40 to 70 years who live in Spain.
- Trial name
- NCT07596069
- Testing
- Reproductive stage, Physical Activity Level
- Where
- 2 sites in Spain
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Cuerpos Serranos S.L.
Hot Flashes, Sleep
Impact of Cooling Mats on Vasomotor Symptoms in Patients Receiving Endocrine Therapy
This research study will investigate whether using a non-drug option, like a cooling mat, made of temperature-regulating materials, can help relieve the discomfort of hot flushes and/or night sweats for people receiving hormone…
- Conditions
- Hot Flashes, Sleep, Hormonal, Cancer
- Trial name
- COOLVAS (NCT07422727)
- Testing
- Cooling Gel Mats
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Sligo General Hospital
Menopause
Satavari and Ashoka for Menopause (SAM) Study
This 12-week randomized, placebo-controlled clinical trial will evaluate the efficacy and safety of a daily oral supplement containing Ashoka Bark and Shatavari in women experiencing menopausal symptoms.
- Trial name
- SAM (NCT07861295)
- Testing
- Ashoka Bark and Shatavari
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vidya USA Corporation
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Hot Flashes, Menopause
Hot Flashes and Neurovascular Function in Women
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship.
- Conditions
- Hot Flashes, Menopause, Vasomotor System; Labile
- Trial name
- NCT05193968
- Testing
- Sympathoexcitatory stressors, Sodium Nitroprusside, Acetylcholine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause, Perimenopause
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition
The goal of this clinical trial is to learn whether it is feasible to conduct a larger study comparing transdermal menopausal hormone therapy (MHT) versus no hormone therapy in menopausal women with vasomotor symptoms (hot…
- Conditions
- Menopause, Perimenopause, Vasomotor Symptoms, Cardiovascular Disease Risk Factor
- Trial name
- HERBRAVEHEART (NCT07732452)
- Testing
- Transdermal estradiol, Standard of care - non hormonal
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Perimenopause, Perimenopausal Depression
A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women
The goal of this observational study is to investigate the accuracy of the device in characterizing perimenopausal and menopausal symptoms including vasomotor symptoms, anxiety, sleep quality compared to self-reported symptoms…
- Conditions
- Perimenopause, Perimenopausal Depression, Perimenopausal Insomnia, Perimenopausal Women
- Trial name
- NCT07022925
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- IdentifyHer Limited
Migraine, Menopausal
Migraine Menopause Study
This study will assess whether the migraine medication eptinezumab (Vyepti) reduces migraine days in women who are in perimenopause and early menopause and who also experience night sweats and hot flashes.
- Conditions
- Migraine, Menopausal, Perimenopause
- Trial name
- NCT07916571
- Testing
- Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution
- Volunteers
- 120 people
- Sponsor
- Alberta Neurologic Centre
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis